دورية أكاديمية
The Importance of Echocardiogram during the Second Week of Illness in Children with Kawasaki Disease.
| العنوان: | The Importance of Echocardiogram during the Second Week of Illness in Children with Kawasaki Disease. |
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| المؤلفون: | Ma S; John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI., Choi SY; Biostatistics Core, Department of Complimentary and Integrative Medicine, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI., Ahn HJ; Biostatistics Core, Department of Complimentary and Integrative Medicine, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI., Siu AM; Hawai'i Pacific Health Research Institute, Hawai'i Pacific Health, Honolulu, HI., Melish ME; Department of Pediatrics, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI; Kapi'olani Medical Specialists, Hawai'i Pacific Health, Honolulu, HI., Bratincsak A; Department of Pediatrics, John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI; Kapi'olani Medical Specialists, Hawai'i Pacific Health, Honolulu, HI. Electronic address: ibrati@me.com. |
| المصدر: | The Journal of pediatrics [J Pediatr] 2020 Mar; Vol. 218, pp. 72-77.e1. Date of Electronic Publication: 2019 Dec 04. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Mosby Country of Publication: United States NLM ID: 0375410 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6833 (Electronic) Linking ISSN: 00223476 NLM ISO Abbreviation: J Pediatr Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: St. Louis, MO : Mosby |
| مواضيع طبية MeSH: | Coronary Aneurysm/*diagnosis , Coronary Vessels/*diagnostic imaging , Echocardiography/*methods , Mucocutaneous Lymph Node Syndrome/*diagnosis, Adolescent ; Child ; Child, Preschool ; Coronary Aneurysm/etiology ; Disease Progression ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Mucocutaneous Lymph Node Syndrome/complications ; Reproducibility of Results ; Retrospective Studies |
| مستخلص: | Objective: To determine the timing of peak coronary artery dilation and the characteristics of patients who present with new-onset coronary artery dilation during the acute phase of Kawasaki disease with an initial normal echocardiogram. Study Design: This retrospective study analyzed 231 children hospitalized for Kawasaki disease in Hawai'i over a period of 7 years. Clinical and echocardiographic data were collected to calculate the timing of peak z score, and study subjects were compared based on the timing of coronary dilation. Results: Peak coronary artery dilation was observed on average at 11.5 days from the onset of fever (median 8, IQR 7-13 days). Among study subjects with normal z scores in both coronary arteries during the initial encounter and echocardiogram (n = 164), 16 (10%) developed coronary artery dilation or aneurysm at the second echocardiogram, and 5 (3%) continued to have coronary artery dilation or aneurysm at the convalescent phase. Conclusions: A repeat echocardiogram during the second week of illness (day 7-14 from fever onset) in patients with normal initial echocardiogram could identify new-onset coronary artery dilation or aneurysm and could be useful in the timely adjustment of antithrombotic or anti-inflammatory therapies. (Copyright © 2019. Published by Elsevier Inc.) |
| فهرسة مساهمة: | Keywords: coronary artery dilation; echocardiogram; kawasaki disease; z score |
| تواريخ الأحداث: | Date Created: 20191208 Date Completed: 20200818 Latest Revision: 20200818 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.jpeds.2019.10.067 |
| PMID: | 31810628 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1097-6833 |
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| DOI: | 10.1016/j.jpeds.2019.10.067 |