دورية أكاديمية
أعرض في EDS

RISK FACTORS FOR SEVERE POSTOPERATIVE COMPLICATIONS AFTER GASTRECTOMY FOR GASTRIC AND ESOPHAGOGASTRIC JUNCTION CANCERS.

التفاصيل البيبلوغرافية
العنوان: RISK FACTORS FOR SEVERE POSTOPERATIVE COMPLICATIONS AFTER GASTRECTOMY FOR GASTRIC AND ESOPHAGOGASTRIC JUNCTION CANCERS.
المؤلفون: Norero E; Hospital Dr. Sotero del Rio, Esophagogastric Surgery Unit, Digestive Surgery Department, Pontificia Universidad Catolica de Chile, Chile., Quezada JL; Hospital Dr. Sotero del Rio, Esophagogastric Surgery Unit, Digestive Surgery Department, Pontificia Universidad Catolica de Chile, Chile., Cerda J; Epidemiology Department, Department of Public Health, Faculty of Medicine, Pontificia Universidad Catolica de Chile, Chile., Ceroni M; Hospital Dr. Sotero del Rio, Esophagogastric Surgery Unit, Digestive Surgery Department, Pontificia Universidad Catolica de Chile, Chile., Martinez C; Hospital Dr. Sotero del Rio, Esophagogastric Surgery Unit, Digestive Surgery Department, Pontificia Universidad Catolica de Chile, Chile., Mejía R; Hospital Dr. Sotero del Rio, Esophagogastric Surgery Unit, Digestive Surgery Department, Pontificia Universidad Catolica de Chile, Chile., Muñoz R; Hospital Dr. Sotero del Rio, Esophagogastric Surgery Unit, Digestive Surgery Department, Pontificia Universidad Catolica de Chile, Chile., Araos F; Hospital Dr. Sotero del Rio, Esophagogastric Surgery Unit, Digestive Surgery Department, Pontificia Universidad Catolica de Chile, Chile., González P; Hospital Dr. Sotero del Rio, Esophagogastric Surgery Unit, Digestive Surgery Department, Pontificia Universidad Catolica de Chile, Chile., Díaz A; Hospital Dr. Sotero del Rio, Esophagogastric Surgery Unit, Digestive Surgery Department, Pontificia Universidad Catolica de Chile, Chile.
المصدر: Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery [Arq Bras Cir Dig] 2019 Dec 20; Vol. 32 (4), pp. e1473. Date of Electronic Publication: 2019 Dec 20 (Print Publication: 2019).
نوع المنشور: Journal Article
اللغة: English; Portuguese
بيانات الدورية: Publisher: Colégio Brasileiro de Cirurgia Digestiva Country of Publication: Brazil NLM ID: 9100283 Publication Model: eCollection Cited Medium: Internet ISSN: 2317-6326 (Electronic) Linking ISSN: 01026720 NLM ISO Abbreviation: Arq Bras Cir Dig Subsets: MEDLINE
أسماء مطبوعة: Publication: São Paulo, Brasil : Colégio Brasileiro de Cirurgia Digestiva
Original Publication: São Paulo, Brasil : Disciplina de Cirurgia do Aparelho Digestivo do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo,
مواضيع طبية MeSH: Esophageal Neoplasms/*surgery , Esophagogastric Junction/*surgery , Gastrectomy/*adverse effects , Postoperative Complications/*epidemiology , Stomach Neoplasms/*surgery, Aged ; Cohort Studies ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors
مستخلص: Background: Gastrectomy is the main treatment for gastric and Siewert type II-III esophagogastric junction (EGJ) cancer. This surgery is associated with significant morbidity. Total morbidity rates vary across different studies and few have evaluated postoperative morbidity according to complication severity.
Aim: To identify the predictors of severe postoperative morbidity.
Methods: This was a retrospective cohort study from a prospective database. We included patients treated with gastrectomy for gastric or EGJ cancers between January 2012 and December 2016 at a single center. Severe morbidity was defined as Clavien-Dindo score ≥3. A multivariate analysis was performed to identify predictors of severe morbidity.
Results: Two hundred and eighty-nine gastrectomies were performed (67% males, median age: 65 years). Tumor location was EGJ in 14%, upper third of the stomach in 30%, middle third in 26%, and lower third in 28%. In 196 (67%), a total gastrectomy was performed with a D2 lymph node dissection in 85%. Two hundred and eleven patients (79%) underwent an open gastrectomy. T status was T1 in 23% and T3/T4 in 68%. Postoperative mortality was 2.4% and morbidity rate was 41%. Severe morbidity was 11% and was mainly represented by esophagojejunostomy leak (2.4%), duodenal stump leak (2.1%), and respiratory complications (2%). On multivariate analysis, EGJ location and T3/T4 tumors were associated with a higher rate of severe postoperative morbidity.
Conclusion: Severe postoperative morbidity after gastrectomy was 11%. Esophagogastric junction tumor location and T3/T4 status are risk factors for severe postoperative morbidity.
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تواريخ الأحداث: Date Created: 20191221 Date Completed: 20200310 Latest Revision: 20200310
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC6918748
DOI: 10.1590/0102-672020190001e1473
PMID: 31859926
قاعدة البيانات: MEDLINE
الوصف
تدمد:2317-6326
DOI:10.1590/0102-672020190001e1473