دورية أكاديمية
Looking into dental pulp stem cells in the therapy of photoreceptors and retinal degenerative disorders.
العنوان: | Looking into dental pulp stem cells in the therapy of photoreceptors and retinal degenerative disorders. |
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المؤلفون: | Alsaeedi HA; Department of Medical Microbiology and Parasitology, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia., Lam C; Department of Ophthalmology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, 56000 Cheras, Kuala Lumpur, Malaysia., Koh AE; Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia., Teh SW; Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia., Mok PL; Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia; Genetics and Regenerative Medicine Research Center, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia; Department of Clinical Laboratory Sciences, College of Applied Medical Science, Jouf University, Sakaka 72442, Aljouf Province, Saudi Arabia., Higuchi A; Department of Chemical and Materials Engineering, National Central University, Jhong-li, Taoyuan 32001, Taiwan; Department of Reproduction, National Research Institute for Child Health and Development, Tokyo 157-8535, Japan., Then KY; Department of Ophthalmology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, 56000 Cheras, Kuala Lumpur, Malaysia., Bastion MC; Department of Ophthalmology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, 56000 Cheras, Kuala Lumpur, Malaysia., Alzahrani B; Department of Clinical Laboratory Sciences, College of Applied Medical Science, Jouf University, Sakaka 72442, Aljouf Province, Saudi Arabia., Farhana A; Department of Clinical Laboratory Sciences, College of Applied Medical Science, Jouf University, Sakaka 72442, Aljouf Province, Saudi Arabia., Muthuvenkatachalam BS; Department of Biochemistry, Faculty of Medicine, AIMST University, Jalan Bedong-Semeling, 08100 Bedong, Kedah, Malaysia., Samrot AV; Department of Biotechnology, School of Bio and Chemical Engineering, Sathyabama Institute of Science and Technology, Jeppiaar Nagar, Rajiv Gandhi Salai, Sholinganallur, Chennai 600119, Tamil Nadu, India; Department of Biomedical Sciences, Faculty of Medicine and Biomedical Sciences, MAHSA University, Jalan SP2, Bandar Saujana Putra, 42810 Jenjarom, Selangor, Malaysia., Swamy KB; Faculty of Medicine, Lincoln University College, Wisma Lincoln, No. 12-18, Jalan SS 6/12, 47301 Petaling Jaya, Selangor Darul Ehsan, Malaysia., Marraiki N; Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia., Elgorban AM; Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia; Centre of Excellence in Biotechnology Research, King Saud University, P.O Box 2455, Riyadh 11451, Saudi Arabia., Subbiah SK; Department of Medical Microbiology and Parasitology, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia; Genetics and Regenerative Medicine Research Center, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia; UPM-MAKNA Cancer Research Centre, Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia. Electronic address: sureshkudsc@gmail.com. |
المصدر: | Journal of photochemistry and photobiology. B, Biology [J Photochem Photobiol B] 2020 Jan; Vol. 203, pp. 111727. Date of Electronic Publication: 2019 Dec 03. |
نوع المنشور: | Journal Article; Review |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier Sequoia Country of Publication: Switzerland NLM ID: 8804966 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2682 (Electronic) Linking ISSN: 10111344 NLM ISO Abbreviation: J Photochem Photobiol B Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Lausanne : Elsevier Sequoia, 1987- |
مواضيع طبية MeSH: | Stem Cell Transplantation*, Dental Pulp/*cytology , Retinal Degeneration/*therapy, Humans ; Photoreceptor Cells/physiology ; Retina/physiology ; Stem Cells/cytology |
مستخلص: | Blindness and vision impairment are caused by irremediable retinal degeneration in affected individuals worldwide. Cell therapy for a retinal replacement can potentially rescue their vision, specifically for those who lost the light sensing photoreceptors in the eye. As such, well-characterized retinal cells are required for the replacement purposes. Stem cell-based therapy in photoreceptor and retinal pigment epithelium transplantation is well received, however, the drawbacks of retinal transplantation is the limited clinical protocols development, insufficient number of transplanted cells for recovery, the selection of potential stem cell sources that can be differentiated into the target cells, and the ability of cells to migrate to the host tissue. Dental pulp stem cells (DPSC) belong to a subset of mesenchymal stem cells, and are recently being studied due to its high capability of differentiating into cells of the neuronal lineage. In this review, we look into the potential uses of DPSC in treating retinal degeneration, and also the current data supporting its application. (Copyright © 2019 Elsevier B.V. All rights reserved.) |
فهرسة مساهمة: | Keywords: Dental pulp stem cell; Photoreceptor; Retina; Retinal degeneration; Stem cell therapy |
تواريخ الأحداث: | Date Created: 20191222 Date Completed: 20200213 Latest Revision: 20200213 |
رمز التحديث: | 20240628 |
DOI: | 10.1016/j.jphotobiol.2019.111727 |
PMID: | 31862637 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1873-2682 |
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DOI: | 10.1016/j.jphotobiol.2019.111727 |