دورية أكاديمية
أعرض في EDS

Epizootiology, Clinical Signs, and Phylogenetic Analysis of Fowl Adenovirus in Chicken Farms in Indonesia from 2018 to 2019.

التفاصيل البيبلوغرافية
العنوان: Epizootiology, Clinical Signs, and Phylogenetic Analysis of Fowl Adenovirus in Chicken Farms in Indonesia from 2018 to 2019.
المؤلفون: Wibowo MH; Microbiology Department, Faculty of Veterinary Medicine Gajah Mada University, Yogjakarta 55281, Indonesia., Sahesty A; Research and Development Department, PT Medion Farma Jaya, Bandung 40552, Indonesia., Mahardika BK; The Animal Biomedical and Molecular Biology Laboratory, Udayana University of Bali, Denpasar 80223, Indonesia., Purwanto B; Research and Development Department, PT Medion Farma Jaya, Bandung 40552, Indonesia., Lestariningsih CL; Research and Development Department, PT Medion Farma Jaya, Bandung 40552, Indonesia., Kade Suardana IB; Virology Department, Faculty of Veterinary Medicine, Udayana University of Bali, Denpasar 80113, Indonesia., Oka Winaya IB; Pathology Department, Faculty of Veterinary Medicine Udayana University of Bali, Denpasar 80113, Indonesia., Irine I; Research and Development Department, PT Medion Farma Jaya, Bandung 40552, Indonesia., Suryanggono J; Research and Development Department, PT Medion Farma Jaya, Bandung 40552, Indonesia., Jonas M; Research and Development Department, PT Medion Farma Jaya, Bandung 40552, Indonesia., Murwijati T; Research and Development Department, PT Medion Farma Jaya, Bandung 40552, Indonesia., Mahardika GN; The Animal Biomedical and Molecular Biology Laboratory, Udayana University of Bali, Denpasar 80223, Indonesia, gnmahardika@unud.ac.id.; Virology Department, Faculty of Veterinary Medicine, Udayana University of Bali, Denpasar 80113, Indonesia, gnmahardika@unud.ac.id.
المصدر: Avian diseases [Avian Dis] 2019 Dec; Vol. 63 (4), pp. 619-624.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: American Association Of Avian Pathologists Country of Publication: United States NLM ID: 0370617 Publication Model: Print Cited Medium: Internet ISSN: 1938-4351 (Electronic) Linking ISSN: 00052086 NLM ISO Abbreviation: Avian Dis Subsets: MEDLINE
أسماء مطبوعة: Publication: Kennett Square Pa : American Association Of Avian Pathologists
Original Publication: Ithaca, N. Y., American Association of Avian Pathologists.
مواضيع طبية MeSH: Chickens* , Poultry Diseases*/epidemiology , Poultry Diseases*/pathology, Adenoviridae Infections/*veterinary , Epidemics/*veterinary , Fowl adenovirus A/*physiology, Adenoviridae Infections/epidemiology ; Adenoviridae Infections/pathology ; Animals ; Fowl adenovirus A/classification ; Indonesia/epidemiology ; Phylogeny ; Specific Pathogen-Free Organisms
مستخلص: Fowl adenovirus (FAdV) infection is an emerging problem in the world poultry industry, especially in broilers, as the causal agent of inclusion body hepatitis or hepatitis-hydropericardium syndrome. From December 2017 to January 2019, we recorded 116 cases of suspected hepatitis-hydropericardium syndrome in chicken farms throughout Indonesia. Necropsy was done on each farm site with three to five freshly dead birds per farm. Tissue samples were collected in virus transport medium and frozen at -20 C. The virus was cultivated in 9-day-old fertilized specific-pathogenic-free chicken eggs. FAdV was detected using polymerase chain reaction with a published primer set. The polymerase chain reaction products were sequenced and subjected to a BLAST search. The phylogeny was inferred using the neighbor-joining method and tested using the bootstrap test. FadV-D and -E are present in Indonesia and confirmed in 40 of 116 suspected cases. The affected chicken ages were 27.27 ± 8.94 days. Most affected farms were raising broiler chickens. The only typical clinical sign was unusual daily mortality of >1%, while the three most frequent pathologic lesions were swelling and hemorrhage of kidney and liver, as well as hydropericardium. To reduce economic loss, a vaccine should be developed immediately.
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فهرسة مساهمة: Keywords: Indonesia; broiler; fowl adenovirus; hepatitis-hydropericardium syndrome; inclusion body hepatitis
Local Abstract: [Publisher, Spanish; Castilian] Epizootiología, signos clínicos y análisis filogenético del adenovirus de pollos en granjas avícolas en Indonesia entre los años 2018 a 2019. La infección por adenovirus de aves (FAdV) es un problema emergente en la industria avícola mundial, especialmente en pollos de engorde, como agente causal de la hepatitis por cuerpos de inclusión y del síndrome de hepatitis-hidropericardio. Desde diciembre del año 2017 hasta enero de 2019, se registraron 116 casos sospechosos de síndrome de hepatitis-hidropericardio en granjas avícolas en toda Indonesia. Se realizaron necropsias en los sitios de las granjas con tres a cinco aves recién muertas por granja. Se recogieron muestras de tejido en medio de transporte viral y se congelaron a -20 C. El virus se cultivó en huevos embrionados de aves libres de patógenos específicos de 9 días de edad. Se detectaron adenovirus del pollo usando una reacción en cadena de la polimerasa con un conjunto de iniciadores previamente publicados. Los productos de reacción en cadena de la polimerasa se secuenciaron y se sometieron a una búsqueda mediante la herramienta básica de búsqueda de alineación local (BLAST). La filogenia se infirió usando el método Neighbor-Joining y se evaluó mediante la prueba bootstrap. Se determinó la presencia de adenovirus del pollo D y E en Indonesia y se confirmó su presencia en 40 de 116 casos sospechosos. Las edades de los pollos afectados fueron de 27.27 ± 8.94 días. Las granjas más afectadas fueron de pollos de engorde. El único signo clínico típico fue una mortalidad diaria inusual mayor al 1%, mientras que las tres lesiones patológicas más frecuentes fueron inflamación y hemorragia de riñón e hígado, así como hidropericardio. Para reducir la pérdida económica, se debe desarrollar una vacuna de inmediato.
تواريخ الأحداث: Date Created: 20191224 Date Completed: 20200604 Latest Revision: 20200604
رمز التحديث: 20231215
DOI: 10.1637/aviandiseases-D-19-00127
PMID: 31865676
قاعدة البيانات: MEDLINE
الوصف
تدمد:1938-4351
DOI:10.1637/aviandiseases-D-19-00127