دورية أكاديمية
Assessment of DNA damage and cholinesterase activity in soybean farmers in southern Brazil: High versus low pesticide exposure.
| العنوان: | Assessment of DNA damage and cholinesterase activity in soybean farmers in southern Brazil: High versus low pesticide exposure. |
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| المؤلفون: | Bernieri T; Health Sciences Institute, Feevale University, Novo Hamburgo, Rio Grande do Sul, Brazil., Moraes MF; Health Sciences Institute, Feevale University, Novo Hamburgo, Rio Grande do Sul, Brazil., Ardenghi PG; Health Sciences Institute, Feevale University, Novo Hamburgo, Rio Grande do Sul, Brazil., Basso da Silva L; Health Sciences Institute, Feevale University, Novo Hamburgo, Rio Grande do Sul, Brazil. |
| المصدر: | Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes [J Environ Sci Health B] 2020; Vol. 55 (4), pp. 355-360. Date of Electronic Publication: 2019 Dec 23. |
| نوع المنشور: | Journal Article; Video-Audio Media |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Country of Publication: England NLM ID: 7607167 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-4109 (Electronic) Linking ISSN: 03601234 NLM ISO Abbreviation: J Environ Sci Health B Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2005- : Abingdon, Oxford : Taylor & Francis Original Publication: New York, Dekker. |
| مواضيع طبية MeSH: | DNA Damage* , Farmers* , Glycine max*, Butyrylcholinesterase/*blood , Occupational Exposure/*analysis , Pesticides/*toxicity, Adult ; Agriculture ; Brazil ; Case-Control Studies ; Cholinesterase Inhibitors/toxicity ; Comet Assay ; Humans ; Male ; Middle Aged ; Time Factors |
| مستخلص: | The aim of this study was to evaluate the DNA damage in soybean growers during two agricultural periods of a crop season (high and low exposure) and a control group, as well as butyrylcholinesterase (BChE) activity during these exposure periods in order to estimate the degree of BChE inhibition for the exposed group. DNA damage in peripheral whole blood was evaluated by the comet assay and plasma BChE activity was accessed as a measure of exposure to cholinesterase inhibitors. None of the soybean growers reported using full Personal Protective Equipment (PPE). BChE was lower in high exposure period than in low exposure period and DNA damage index was significantly increased in the high exposure period than in the low exposure period. In addition, DNA damage in both exposure periods was higher than control group. No correlation was found between exposure time and DNA damage and BChE activity. However, negative correlation was observed between DNA damage in high and low exposure periods. The results indicate that soybean growers are exposed to cholinesterase inhibitors and to pesticides mixtures with genotoxic potential. |
| فهرسة مساهمة: | Keywords: BChE; Comet assay; pesticides exposure; plasmatic cholinesterase |
| المشرفين على المادة: | 0 (Cholinesterase Inhibitors) 0 (Pesticides) EC 3.1.1.8 (Butyrylcholinesterase) |
| تواريخ الأحداث: | Date Created: 20191224 Date Completed: 20200504 Latest Revision: 20231213 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1080/03601234.2019.1704608 |
| PMID: | 31868080 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1532-4109 |
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| DOI: | 10.1080/03601234.2019.1704608 |