تقرير
Oxidative storm in a patient with acute rotenone-containing plant poisoning.
| العنوان: | Oxidative storm in a patient with acute rotenone-containing plant poisoning. |
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| المؤلفون: | Yu JH; Department of Emergency Medicine, China Medical University Hospital, Hsinchu, Taiwan. Electronic address: flykingyu@gmail.com., Huang CF; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan; Department of Nursing, College of Medical and Health Science, Asia University, Taichung, Taiwan., Wang TH; Department of Emergency Medicine, National Yang-Ming University Hospital, Taiwan., Hung DZ; Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan., Mu HW; Department of Emergency Medicine, China Medical University Hospital, Taichung, Taiwan., Pan CS; Department of Emergency Medicine, China Medical University Hospital, Taichung, Taiwan. |
| المصدر: | The American journal of emergency medicine [Am J Emerg Med] 2020 Jun; Vol. 38 (6), pp. 1296.e1-1296.e3. Date of Electronic Publication: 2020 Jan 09. |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: W B Saunders Country of Publication: United States NLM ID: 8309942 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8171 (Electronic) Linking ISSN: 07356757 NLM ISO Abbreviation: Am J Emerg Med Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 1983- : Philadelphia, PA : W B Saunders Original Publication: [Philadelphia, PA. : Centrum Philadelphia, c1983]- |
| مواضيع طبية MeSH: | Pachyrhizus/*adverse effects , Rotenone/*analysis, Acidosis, Lactic/complications ; Acidosis, Lactic/etiology ; Coma/etiology ; Female ; Humans ; Middle Aged ; Oxidative Stress/drug effects ; Rotenone/adverse effects ; Rotenone/blood ; Seizures/etiology |
| مستخلص: | A 64-year-old woman presented with coma, seizure, and lactic acidosis after ingesting 80 yam bean seeds. This rotenone-containing seeds cause cellular asphyxia via blockage of the mitochondrial electron transport. Subsequent oxidative stress results in the formation of lipid peroxidation (LPO). Rotenone analysis via liquid chromatography mass spectrometry revealed the following: 31,590 ng/mL in cooked yam bean seed and 100 ng/mL in the blood. We attempted to use N-acetylcysteine to alleviate oxidative stress and documented the continuous decline in the plasma concentration of LPO. Competing Interests: Declaration of competing interest The authors report no conflicts of interest. (Copyright © 2020 Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Lipid peroxidation; N-acetylcysteine; Reactive oxygen species; Rotenone; Yam bean seed poisoning |
| المشرفين على المادة: | 03L9OT429T (Rotenone) |
| تواريخ الأحداث: | Date Created: 20200121 Date Completed: 20200824 Latest Revision: 20200824 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.ajem.2020.01.019 |
| PMID: | 31956048 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1532-8171 |
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| DOI: | 10.1016/j.ajem.2020.01.019 |