دورية أكاديمية

Novel human reovirus isolated from children and its long-term circulation with reassortments.

التفاصيل البيبلوغرافية
العنوان: Novel human reovirus isolated from children and its long-term circulation with reassortments.
المؤلفون: Yamamoto SP; Division of Microbiology, Osaka Institute of Public Health, Osaka, 543-0026, Japan. yamamotosei@iph.osaka.jp., Motooka D; Research Institute for Microbial Diseases, Osaka University, Osaka, 565-0871, Japan., Egawa K; Division of Microbiology, Osaka Institute of Public Health, Osaka, 543-0026, Japan., Kaida A; Division of Microbiology, Osaka Institute of Public Health, Osaka, 543-0026, Japan., Hirai Y; Division of Microbiology, Osaka Institute of Public Health, Osaka, 543-0026, Japan., Kubo H; Division of Microbiology, Osaka Institute of Public Health, Osaka, 543-0026, Japan., Motomura K; Division of Microbiology, Osaka Institute of Public Health, Osaka, 543-0026, Japan., Nakamura S; Research Institute for Microbial Diseases, Osaka University, Osaka, 565-0871, Japan., Iritani N; Division of Public Health, Osaka Institute of Public Health, Osaka, 537-0025, Japan.
المصدر: Scientific reports [Sci Rep] 2020 Jan 22; Vol. 10 (1), pp. 963. Date of Electronic Publication: 2020 Jan 22.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : Nature Publishing Group, copyright 2011-
مواضيع طبية MeSH: Genome, Viral*, Orthoreovirus, Mammalian/*isolation & purification , Reoviridae Infections/*virology, Child ; Humans ; Japan ; Orthoreovirus, Mammalian/genetics
مستخلص: Mammalian orthoreovirus (MRV), also known as reovirus, was discovered in the 1950s and became the first reported segmented double-stranded RNA virus. MRVs have since been found in a variety of animal species, including humans. However, reports on MRV infections are scarce due to the rarity of their symptomatic occurrence. In Japanese surveillance studies, MRVs have been detected as gastrointestinal pathogens since 1981, with a total of 135 records. In Osaka City, Japan, MRV was first isolated in 1994 from a child with meningitis, and then in 2005 and 2014 from children with gastroenteritis. Here, we conducted the first molecular characterization of human MRV isolates from Japan and identified a novel human reovirus strain belonging to MRV type 2, designated the MRV-2 Osaka strain. This strain, with all three isolates classified, is closely related to MRV-2 isolates from sewage in Taiwan and is relatively close to an MRV-2 isolate from a bat in China. Our data suggest that the MRV-2 Osaka strain, which has circulated amongst humans in Japan for at least two decades, has spread internationally.
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تواريخ الأحداث: Date Created: 20200124 Date Completed: 20201119 Latest Revision: 20210121
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC6976588
DOI: 10.1038/s41598-020-58003-9
PMID: 31969658
قاعدة البيانات: MEDLINE
الوصف
تدمد:2045-2322
DOI:10.1038/s41598-020-58003-9