دورية أكاديمية
أعرض في EDS

Environmental Exposure of Arsenic in Groundwater Associated to Carcinogenic Risk in Underweight Children Exposed to Fluorides.

التفاصيل البيبلوغرافية
العنوان: Environmental Exposure of Arsenic in Groundwater Associated to Carcinogenic Risk in Underweight Children Exposed to Fluorides.
المؤلفون: Molina-Frechero N; Division of Biological and Health Sciences, Universidad Autónoma Metropolitana, Mexico City 04460, Mexico., Nevarez-Rascón M; Faculty of Dentistry, Universidad Autónoma de Chihuahua, Chihuahua 31000, Mexico., Tremillo-Maldonado O; Research Department, Faculty of Dentistry, Universidad Juárez del Estado de Durango, Durango 34000, Mexico., Vergara-Onofre M; Division of Biological and Health Sciences, Universidad Autónoma Metropolitana, Mexico City 04460, Mexico., Gutiérrez-Tolentino R; Division of Biological and Health Sciences, Universidad Autónoma Metropolitana, Mexico City 04460, Mexico., Gaona E; Division of Biological and Health Sciences, Universidad Autónoma Metropolitana, Mexico City 04460, Mexico., Castañeda E; Division of Biological and Health Sciences, Universidad Autónoma Metropolitana, Mexico City 04460, Mexico., Jarquin-Yañez L; Center of Applied Research in Environment and Health, CIACYT, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78120, Mexico., Bologna-Molina R; Research Department, Faculty of Dentistry, Universidad Juárez del Estado de Durango, Durango 34000, Mexico.; Molecular Pathology, School of Dentistry, Universidad de la República, Montevideo 11600, Uruguay.
المصدر: International journal of environmental research and public health [Int J Environ Res Public Health] 2020 Jan 22; Vol. 17 (3). Date of Electronic Publication: 2020 Jan 22.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101238455 Publication Model: Electronic Cited Medium: Internet ISSN: 1660-4601 (Electronic) Linking ISSN: 16604601 NLM ISO Abbreviation: Int J Environ Res Public Health Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel : MDPI, c2004-
مواضيع طبية MeSH: Environmental Exposure* , Neoplasms* , Thinness*, Arsenic/*adverse effects , Groundwater/*analysis , Water Pollutants, Chemical/*adverse effects, Adult ; Child ; Cities ; Drinking Water/analysis ; Environmental Monitoring ; Fluorides ; Humans ; Mexico ; Risk Assessment
مستخلص: Background: The purpose of this study was to determine the concentration of inorganic arsenic (As) in the potable water available to the population to be able to estimate the non-carcinogenic risks for underweight children and the carcinogenic risk for adults exposed to As intake who live in the Mezquital municipality, Durango, Mexico.
Methods: The As content was quantifed in the water supply sources for human use and its intake was estimated in Mezquital population, southern Durango. With the data obtained, the hazard quotient (HQ) was calculated to determine the non-carcinogenic risk to develop chronic systemic effects in underweight children. The Environmental Protection Agency (EPA) reference health values estimating As exposure risk are from 0.0003 mg/kg/day (non-carcinogenic) to 1.5 mg/kg/day (carcinogenic risk).
Results: The analyzed waters presented as concentrations that varied from 0.3 to 10.2 µg/L, with a mean of 7.35 µg/L (CI 95% 6.27-8.38). The exposure dose was 0.4 to 1.36, and the HQ was 1.90 to 6.48 mg/kg/day, the estimated carcinogenic risk from adults varied from 1.28 to 4.37E -4 , with values of 3.74-4.37E -4 mg/kg/day in central area.
Conclusions: The children are at risk to develop chronic systemic effects due to ingestion of As from water.
Competing Interests: The authors have no conflicts of interest.
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فهرسة مساهمة: Keywords: arsenic; carcinogenic risk; exposure dose; hazard quotient; non-carcinogenic
المشرفين على المادة: 0 (Drinking Water)
0 (Water Pollutants, Chemical)
N712M78A8G (Arsenic)
Q80VPU408O (Fluorides)
تواريخ الأحداث: Date Created: 20200126 Date Completed: 20201002 Latest Revision: 20201002
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC7036991
DOI: 10.3390/ijerph17030724
PMID: 31979150
قاعدة البيانات: MEDLINE
الوصف
تدمد:1660-4601
DOI:10.3390/ijerph17030724