دورية أكاديمية
Risks associated with pathogenic fungi isolated from surgical centers, intensive care units, and materials sterilization center in hospitals. Risks associated with pathogenic fungi isolated from critical hospital areas.
| العنوان: | Risks associated with pathogenic fungi isolated from surgical centers, intensive care units, and materials sterilization center in hospitals. Risks associated with pathogenic fungi isolated from critical hospital areas. |
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| المؤلفون: | de Oliveira MT; Research Laboratory of Medicines and Food Microbiology, Faculty of Pharmacy, Federal University of Goiás, Brazil., Batista NKR; Research Laboratory of Medicines and Food Microbiology, Faculty of Pharmacy, Federal University of Goiás, Brazil., Gil ES; Pharmaceutical and Environmental Analysis Laboratory, Faculty of Pharmacy, Federal University of Goiás, Brazil., Silva MDRR; Laboratory of Mycology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Brazil., Costa CR; Laboratory of Mycology, Institute of Tropical Pathology and Public Health, Federal University of Goiás, Brazil., Bara MTF; Research Laboratory of Natural Products, Faculty of Pharmacy, Federal University of Goiás, Brazil., Torres IMS; Research Laboratory of Medicines and Food Microbiology, Faculty of Pharmacy, Federal University of Goiás, Brazil. |
| المصدر: | Medical mycology [Med Mycol] 2020 Oct 01; Vol. 58 (7), pp. 881-886. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 9815835 Publication Model: Print Cited Medium: Internet ISSN: 1460-2709 (Electronic) Linking ISSN: 13693786 NLM ISO Abbreviation: Med Mycol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2014- : Oxford : Oxford University Press Original Publication: Oxford : Blackwell Science, c1998- |
| مواضيع طبية MeSH: | Antifungal Agents/*administration & dosage , Aspergillus/*isolation & purification , Durable Medical Equipment/*microbiology , Fusarium/*isolation & purification , Iatrogenic Disease/*prevention & control , Penicillium/*isolation & purification , Sterilization/*methods, Humans ; Intensive Care Units ; Operating Rooms ; Prospective Studies ; Recovery Room ; Risk Assessment |
| مستخلص: | The hospital environment requires special attention to air quality, since it needs to be healthy for the protection of patients and health professionals in order to prevent them against hospital infections. The objective of this study was to isolate, identify and evaluate the susceptibility profile of isolated fungi from two hospitals. For air sampling the impaction (Spin Air, IUL®) and passive sedimentation methods were used. For the isolation of fungi from surfaces, contact plates (RODAC®) were used. The identification of the fungi was performed by observing the macroscopic and microscopic aspects of the colonies, whereas for better visualization of fruiting structures, the microculture technique was performed on slides. To evaluate the susceptibility profile, the broth microdilution test recommended by CLSI was performed. Thirty-five isolates were identified: Aspergillus flavus (12), Aspergillus fumigatus (11), Aspergillus niger (1), Aspergillus terreus (2), Penicillium spp. (7), and Fusarium spp. (2) in the hospitals evaluated. All isolates had a minimum inhibitory concentration (MIC) more than 128 μg/ml for fluconazole; 0.5 to 4.0 μg/ml for amphotericin B (hospital 1), and all isolates from haospital 2 had MIC ≥2.0 μg/ml. In hospital 1, MIC for posaconazole ranged from 0.25 μg/ml to ≥32 μg/ml, and hospital 2 ranged from 0.5 to 1.0 μg/ml. The monitoring and evaluation of air quality and surfaces are essential measures for prevention and control of hospital infections, as these microorganisms are becoming increasingly resistant to antimicrobial agents, thus making treatment difficult, especially in immunocompromised individuals. (© The Author(s) 2020. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology.) |
| فهرسة مساهمة: | Keywords: environmental monitoring; filamentous fungi; hospital infections |
| المشرفين على المادة: | 0 (Antifungal Agents) |
| تواريخ الأحداث: | Date Created: 20200206 Date Completed: 20210526 Latest Revision: 20210526 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1093/mmy/myaa004 |
| PMID: | 32022862 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 1460-2709 |
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| DOI: | 10.1093/mmy/myaa004 |