دورية أكاديمية

Determinants of Asymptomatic Bacteriuria in HIV-positive and Negative Pregnant Women in Sagamu, South-West Nigeria.

التفاصيل البيبلوغرافية
العنوان: Determinants of Asymptomatic Bacteriuria in HIV-positive and Negative Pregnant Women in Sagamu, South-West Nigeria.
المؤلفون: Akadri AA; Departments of Obstetrics and Gynaecology, Babcock University, Ilishan-Remo, Ogun State, Nigeria., Odelola OI; Department of Obstetrics and Gynecology, Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, Nigeria.
المصدر: West African journal of medicine [West Afr J Med] 2020 Jan-Mar; Vol. 37 (1), pp. 1-6.
نوع المنشور: Journal Article
اللغة: English; French
بيانات الدورية: Publisher: West African College Of Physicians And West African College Of Surgeons Country of Publication: Nigeria NLM ID: 8301891 Publication Model: Print Cited Medium: Print ISSN: 0189-160X (Print) Linking ISSN: 0189160X NLM ISO Abbreviation: West Afr J Med Subsets: MEDLINE
أسماء مطبوعة: Publication: Lagos : West African College Of Physicians And West African College Of Surgeons
Original Publication: [Yaba, Lagos, Nigeria] : West African College of Physicians and West African College of Surgeons, [1981-
مواضيع طبية MeSH: HIV Seronegativity*, Bacteria/*isolation & purification , Bacteriuria/*microbiology , Bacteriuria/*urine , HIV Infections/*complications , Pregnancy Complications, Infectious/*microbiology , Pregnancy Complications, Infectious/*urine , Urine/*microbiology, Adult ; Bacteriuria/epidemiology ; Cross-Sectional Studies ; Female ; HIV Infections/virology ; Humans ; Nigeria/epidemiology ; Pregnancy ; Pregnancy Complications, Infectious/epidemiology ; Prevalence ; Urinary Tract Infections/epidemiology ; Urinary Tract Infections/microbiology ; Urinary Tract Infections/urine
مستخلص: Background: Pregnant women with asymptomatic bacteriuria are at increased risk of developing symptomatic urinary tract infections. HIV infection may modify the acquisition of bacteriuria in pregnancy.
Objective: To identify the determinants of asymptomatic bacteriuria in HIV-positive and HIV-negative pregnant women in Olabisi Onabanjo University Teaching Hospital, Sagamu, Nigeria.
Methods: A cross-sectional study involving 211 HIV-positive pregnant women and 422 HIV-negative pregnant women attending their first antenatal clinic between October 2017 and March 2018. Information on socio-demographic characteristics and risk factors for asymptomatic bacteriuria in study participants was recorded. Microbial culture was carried out on aseptically collected urine samples.
Results: Asymptomatic bacteriuria was found in 66(31.3%) and 118(28.0%) in HIV-positive and negative women respectively. Advanced maternal age, gestational age above 20 weeks, low socioeconomic status, history of urinary tract infections in previous pregnancies and low CD4 cell count had statistically significant association with increased prevalence of asymptomatic bacteriuria among HIV positive women. Binary logistic regression analysis showed that low socioeconomic status and history of urinary tract infections in previous pregnancies were strong determinants of asymptomatic bacteriuria among HIV positive women (AOR 4.1, CI 1.9-8.7, P < 0.001; AOR 5.8, CI 2.5-13.6, P < 0.001 respectively). In HIV negative women, gestational age above 20 weeks had statistically significant association with increased prevalence of asymptomatic bacteriuria (AOR= 2.34, CI 1.3-4.1, P= 0.002).
Conclusion: Low socioeconomic status and previous history of urinary tract infections are determinants of asymptomatic bacteriuria in HIV positive women while gestational age above 20 weeks is a determinant in HIV negative women. These determinants could be used to identify women at high risk of asymptomatic bacteriuria for targeted screening.
تواريخ الأحداث: Date Created: 20200208 Date Completed: 20200306 Latest Revision: 20200306
رمز التحديث: 20221213
PMID: 32030704
قاعدة البيانات: MEDLINE