تقرير
The Effectiveness of the Low-Level Laser, Antibiotic and Surgical Therapy in the Treatment of Medication-Related Osteonecrosis of the Jaws: A Case Report.
| العنوان: | The Effectiveness of the Low-Level Laser, Antibiotic and Surgical Therapy in the Treatment of Medication-Related Osteonecrosis of the Jaws: A Case Report. |
|---|---|
| المؤلفون: | Del Pilar Rodríguez-Sánchez M; Montería Dental School Univ. del Sinú - UNISINU, Estrada 1w, 38-153, CEP: 4536534, Montería-COR, Colombia., Statkievicz C; São Paulo State University (UNESP), School of Dentistry, Department of Surgery and Integrated Clinic, R. José Bonifácio, 1193, CEP: 16015-050, Araçatuba-SP, Brazil., de Mello-Neto JM; São Paulo State University (UNESP), School of Dentistry, Department of Surgery and Integrated Clinic, R. José Bonifácio, 1193, CEP: 16015-050, Araçatuba-SP, Brazil., Toro LF; São Paulo State University (UNESP), Institute of Biosciences, R. Professor Dr. Antônio Celso Wagner Zanin, 250, CEP: 18618-689, Botucatu-SP, Brazil., Bassi APF; São Paulo State University (UNESP), School of Dentistry, Department of Surgery and Integrated Clinic, R. José Bonifácio, 1193, CEP: 16015-050, Araçatuba-SP, Brazil., Garcia VG; São Paulo State University (UNESP), School of Dentistry, Department of Surgery and Integrated Clinic, R. José Bonifácio, 1193, CEP: 16015-050, Araçatuba-SP, Brazil., Theodoro LH; São Paulo State University (UNESP), School of Dentistry, Department of Surgery and Integrated Clinic, R. José Bonifácio, 1193, CEP: 16015-050, Araçatuba-SP, Brazil., Ervolino E; São Paulo State University (UNESP), School of Dentistry, Department of Basic Sciences, R. José Bonifácio, 1193, CEP: 16015-050, Araçatuba-SP, Brazil. São Paulo State University (UNESP), Institute of Biosciences, R. Professor Dr. Antônio Celso Wagner Zanin, 250, CEP: 18618-689, Botucatu-SP, Brazil. |
| المصدر: | Journal of lasers in medical sciences [J Lasers Med Sci] 2020 Winter; Vol. 11 (1), pp. 98-103. Date of Electronic Publication: 2020 Jan 18. |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: Laser Application in Medical Sciences Research Center Country of Publication: Iran NLM ID: 101580415 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2008-9783 (Print) Linking ISSN: 20089783 NLM ISO Abbreviation: J Lasers Med Sci Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Tehran, Iran : Laser Application in Medical Sciences Research Center |
| مستخلص: | Introduction: Bisphosphonates consist of a range of drugs used in the treatment of osteopathy or some osteotropic malignancies. Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse consequence of their use. Conventional treatment is not always effective, so it is necessary to resort to the use of adjuvant therapies. This study aimed to evaluate the effectiveness of the association of surgery, antibiotic therapy and low-level laser (LLL) therapy as a treatment strategy for MRONJ through the presentation of a clinical case. Case Presentation: A 49-year-old female patient presented for the diagnosis and treatment of bone lesions in the maxillae. The patient reported that she had used zoledronate for 1 year. Five years later there were 2 painless bone lesions on both sides of the maxilla, following the extraction of the first upper molars. Clinical, tomographic and histopathologic examination established the diagnosis of MRONJ. The treatment consisted of the curettage of the necrotic bone, antibiotic and thirteen LLL therapy sessions. Integral mucosal healing was observed after a two-month follow-up and no symptoms were detected. The patient was evaluated at 6 and 12 postoperative months without complications. Conclusion: The combination of surgery, antibiotic therapy, and LLL therapy has shown to be effective in the treatment of MRONJ. (Copyright © 2020 J Lasers Med Sci.) |
| References: | Bone. 2007 Sep;41(3):318-20. (PMID: 17572168) J Oral Maxillofac Surg. 2011 Feb;69(2):362-80. (PMID: 21122968) Lasers Med Sci. 2016 Aug;31(6):1261-72. (PMID: 27025860) J Photochem Photobiol B. 2018 Jul;184:7-17. (PMID: 29777942) Int J Oral Maxillofac Surg. 2014 Nov;43(11):1391-3. (PMID: 25128260) Med Oral Patol Oral Cir Bucal. 2013 Jul 01;18(4):e680-5. (PMID: 23524436) Altern Ther Health Med. 2016 Nov;22(6):24-31. (PMID: 27866178) Dent Clin North Am. 2008 Jan;52(1):111-28, ix. (PMID: 18154867) J Lasers Med Sci. 2013 Summer;4(3):120-6. (PMID: 25606319) J Oral Maxillofac Surg. 2015 Nov;73(11):2082-6. (PMID: 26183009) Lasers Med Sci. 2013 May;28(3):845-9. (PMID: 22843310) Lasers Med Sci. 2015 Feb;30(2):635-43. (PMID: 23835780) J Oral Maxillofac Surg. 2014 Oct;72(10):1938-56. (PMID: 25234529) Photomed Laser Surg. 2011 Jul;29(7):447-52. (PMID: 21235406) Lasers Surg Med. 2016 Dec;48(10):955-964. (PMID: 27454457) IEEE J Sel Top Quantum Electron. 2016 May-Jun;22(3):. (PMID: 28070154) Mayo Clin Proc. 2008 Sep;83(9):1032-45. (PMID: 18775204) J Photochem Photobiol B. 2016 Oct;163:14-21. (PMID: 27521889) J Oral Maxillofac Surg. 2003 Sep;61(9):1115-7. (PMID: 12966493) Int J Dent. 2014;2014:107690. (PMID: 24648841) J Craniofac Surg. 2015 May;26(3):696-9. (PMID: 25915674) Photomed Laser Surg. 2004 Aug;22(4):323-9. (PMID: 15345176) Lasers Med Sci. 2017 Jan;32(1):35-43. (PMID: 27649960) Photomed Laser Surg. 2014 Aug;32(8):468-75. (PMID: 25045921) Int J Oral Maxillofac Surg. 2014 Aug;43(8):1030-4. (PMID: 24656494) Lasers Med Sci. 2015 Feb;30(2):719-26. (PMID: 23929563) Support Care Cancer. 2016 Sep;24(9):3687-93. (PMID: 27029476) Photomed Laser Surg. 2010 Apr;28(2):179-84. (PMID: 19795990) Ann Oncol. 2012 May;23(5):1341-7. (PMID: 21986094) Oral Oncol. 2012 Jan;48(1):79-84. (PMID: 21940198) Br J Oral Maxillofac Surg. 2015 Nov;53(9):870-4. (PMID: 26392134) J Oral Maxillofac Surg. 2009 May;67(5 Suppl):96-106. (PMID: 19371820) Int J Oral Maxillofac Surg. 2014 Mar;43(3):373-80. (PMID: 24021731) Photomed Laser Surg. 2016 Sep;34(9):406-10. (PMID: 27420732) Med Oral Patol Oral Cir Bucal. 2008 May 01;13(5):E318-24. (PMID: 18449117) Arch Oral Biol. 2012 Jul;57(7):884-91. (PMID: 22365421) Int J Oral Maxillofac Surg. 2012 Nov;41(11):1410-5. (PMID: 22647765) J Craniomaxillofac Surg. 2012 Jun;40(4):303-9. (PMID: 21676622) |
| فهرسة مساهمة: | Keywords: Anti-bacterial agents; Diphosphonates; Laser therapy; Oral surgical procedures; Osteonecrosis |
| تواريخ الأحداث: | Date Created: 20200227 Latest Revision: 20200928 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC7008748 |
| DOI: | 10.15171/jlms.2020.16 |
| PMID: | 32099634 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2008-9783 |
|---|---|
| DOI: | 10.15171/jlms.2020.16 |