دورية أكاديمية
Effects of a dopamine agonist on trusting behaviors in females.
| العنوان: | Effects of a dopamine agonist on trusting behaviors in females. |
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| المؤلفون: | Bellucci G; Department of Psychology I, University of Lübeck, 23562, Lübeck, Germany. gbellucc@gmail.com.; Department of Computational Neuroscience, Max Planck Institute for Biological Cybernetics, Tübingen, Germany. gbellucc@gmail.com., Münte TF; Department of Neurology, Universitätsklinikum Schleswig-Holstein, 23538, Lübeck, Germany.; Department of Psychology II, University of Lübeck, 23562, Lübeck, Germany., Park SQ; Department of Psychology I, University of Lübeck, 23562, Lübeck, Germany.; Decision Neuroscience and Nutrition, German Institute of Human Nutrition (DIfE), Potsdam-Rehbruecke, Nuthetal, Germany.; Corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Neuroscience Research Center, Charité-Universitätsmedizin Berlin, 10117, Berlin, Germany.; Deutsches Zentrum für Diabetes, 85764, Neuherberg, Germany. |
| المصدر: | Psychopharmacology [Psychopharmacology (Berl)] 2020 Jun; Vol. 237 (6), pp. 1671-1680. Date of Electronic Publication: 2020 Feb 27. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 7608025 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2072 (Electronic) Linking ISSN: 00333158 NLM ISO Abbreviation: Psychopharmacology (Berl) Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Berlin, New York, Springer-Verlag. |
| مواضيع طبية MeSH: | Facial Expression* , Interpersonal Relations*, Dopamine Agonists/*pharmacology , Photic Stimulation/*methods , Trust/*psychology, Adult ; Attitude ; Brain/drug effects ; Brain/physiology ; Double-Blind Method ; Female ; Humans ; Pramipexole/pharmacology ; Random Allocation ; Young Adult |
| مستخلص: | Trust is central to bonding and cooperation. In many social interactions, individuals need to trust another person exclusively on the basis of their subjective impressions of the other's trustworthiness. Such impressions can be formed from social information from faces (e.g., facial trustworthiness and attractiveness) and guide trusting behaviors via activations of dopaminergic brain regions. However, the specific dopaminergic effects on impression-based trust are to date elusive. Here, in a double-blind, placebo-controlled, within-subject design, we administrated a D2/D3 dopamine agonist (pramipexole) to 28 healthy females who subsequently played a one-shot trust game with partners of varying facial trustworthiness. Our results show that by minimizing facial attractiveness information, we could isolate the specific effects of facial trustworthiness on trust in unknown partners. Despite no modulation of trustworthiness impressions, pramipexole intake significantly impacted trusting behaviors. Notably, these effects of pramipexole on trusting behaviors interacted with participants' hormonal contraceptive use. In particular, after pramipexole intake, trust significantly decreased in hormonal contraceptive non-users. This study fills an important gap in the experimental literature on trust and its neural dynamics, unearthing the cognitive and neural modulations of trusting behaviors based on trustworthiness impressions of others. |
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| معلومات مُعتمدة: | INST 392/125-1 (SFB TRR (07)) Deutsche Forschungsgemeinschaft; PA 2682/1-1 Deutsche Forschungsgemeinschaft; PA 2683/2-1 (FOR 2698/1, TP3) Deutsche Forschungsgemeinschaft; SFB TR134 C1 Deutsche Forschungsgemeinschaft; DZD, FKZ grant 82DZD00302 Bundesministerium für Bildung und Forschung |
| فهرسة مساهمة: | Keywords: Attractiveness; Dopamine; Hormonal contraceptive; Investment game; Trust game; Trusting behavior; Trustworthiness |
| المشرفين على المادة: | 0 (Dopamine Agonists) 83619PEU5T (Pramipexole) |
| تواريخ الأحداث: | Date Created: 20200229 Date Completed: 20201006 Latest Revision: 20210208 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1007/s00213-020-05488-x |
| PMID: | 32107571 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1432-2072 |
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| DOI: | 10.1007/s00213-020-05488-x |