دورية أكاديمية
أعرض في EDS

Patients with axial spondyloarthritis report significant differences between men and women and high impact of the disease: Large websurvey analysis.

التفاصيل البيبلوغرافية
العنوان: Patients with axial spondyloarthritis report significant differences between men and women and high impact of the disease: Large websurvey analysis.
المؤلفون: Ibáñez Vodnizza SE; Department of Rheumatology, Clínica Alemana, Universidad del Desarrollo medicine Faculty, 1410, Av. Manquehue Norte, 7650567 Vitacura, Santiago, Chile. Electronic address: sibanez@alemana.cl., van Bentum RE; Department of Rheumatology, Amsterdam University Medical Center, location VUmc, 1117, De Boelelaan, 1081HV Amsterdam, Netherlands., Valenzuela O; Department of Rheumatology, Clínica Alemana, Universidad del Desarrollo medicine Faculty, 1410, Av. Manquehue Norte, 7650567 Vitacura, Santiago, Chile., van der Horst-Bruinsma IE; Department of Rheumatology, Amsterdam University Medical Center, location VUmc, 1117, De Boelelaan, 1081HV Amsterdam, Netherlands.
المصدر: Joint bone spine [Joint Bone Spine] 2020 Jul; Vol. 87 (4), pp. 315-319. Date of Electronic Publication: 2020 Feb 25.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Editions Elsevier Country of Publication: France NLM ID: 100938016 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1778-7254 (Electronic) Linking ISSN: 1297319X NLM ISO Abbreviation: Joint Bone Spine Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Paris : Editions Elsevier, c2000-
مواضيع طبية MeSH: Spondylarthritis*/diagnosis , Spondylarthritis*/drug therapy , Spondylarthritis*/epidemiology, Absenteeism ; Cross-Sectional Studies ; Female ; Humans ; Male ; Presenteeism ; Severity of Illness Index ; Surveys and Questionnaires
مستخلص: Objective: In axial spondyloarthritis (axSpA), mounting evidence shows female patients to experience a higher disease burden. These differences appear to be particularly large in South America. One explanation could be inequity in treatment access between men and women. The objective was to evaluate gender differences in disease burden and work participation, and the potential influence of treatment, in Latin American patients.
Methods: A cross sectional online survey among axSpA patients, collecting disease characteristics, treatment, disease burden (BASDAI, BASFI, ASAS Health Index) and work participation (WPAI). Associations between gender and disease burden or work participation were assessed through regression analyses, correcting for treatment.
Results: AxSpA was reported by 472 participants (63% women) and disease activity (BASDAI≥4: 83%), ASASHI (≥moderately impaired: 91%) and work disability (absenteeism: 41%; presenteeism 82%) were high. Biological use was very low (20%), while 34% used opiates. Females had significantly higher BASDAI, ASAS HI, work absenteeism and presenteeism, although were less likely to receive biologics (26% versus 16%, P<0.01). Gender differences disappeared after correction for treatment.
Conclusions: This web survey in Latin American axSpA patients shows a high disease burden and work impairment. The use of biologics is low, while the use of opiates was alarmingly high. Women used significantly less biologics despite reporting a worse disease state and work disability, which could be due to treatment inequity.
(Copyright © 2020 Société française de rhumatologie. Published by Elsevier Masson SAS. All rights reserved.)
فهرسة مساهمة: Keywords: Biologics; Burden; Chile; Gender; Spondyloarthritis
تواريخ الأحداث: Date Created: 20200229 Date Completed: 20210625 Latest Revision: 20210625
رمز التحديث: 20240628
DOI: 10.1016/j.jbspin.2020.02.004
PMID: 32109577
قاعدة البيانات: MEDLINE
الوصف
تدمد:1778-7254
DOI:10.1016/j.jbspin.2020.02.004