دورية أكاديمية
أعرض في EDS

Oxidative Stress Biomarkers, Nut-Related Antioxidants, and Cardiovascular Disease.

التفاصيل البيبلوغرافية
العنوان: Oxidative Stress Biomarkers, Nut-Related Antioxidants, and Cardiovascular Disease.
المؤلفون: Lorenzon Dos Santos J; Graduate Program in Health Sciences (Cardiology), Institute of Cardiology of Rio Grande do Sul/University Foundation of Cardiology (IC/FUC), Princesa Isabel Avenue, 395, Porto Alegre, Rio Grande do Sul 90040-371, Brazil., Quadros AS; Graduate Program in Health Sciences (Cardiology), Institute of Cardiology of Rio Grande do Sul/University Foundation of Cardiology (IC/FUC), Princesa Isabel Avenue, 395, Porto Alegre, Rio Grande do Sul 90040-371, Brazil., Weschenfelder C; Graduate Program in Health Sciences (Cardiology), Institute of Cardiology of Rio Grande do Sul/University Foundation of Cardiology (IC/FUC), Princesa Isabel Avenue, 395, Porto Alegre, Rio Grande do Sul 90040-371, Brazil., Garofallo SB; Graduate Program in Health Sciences (Cardiology), Institute of Cardiology of Rio Grande do Sul/University Foundation of Cardiology (IC/FUC), Princesa Isabel Avenue, 395, Porto Alegre, Rio Grande do Sul 90040-371, Brazil., Marcadenti A; Graduate Program in Health Sciences (Cardiology), Institute of Cardiology of Rio Grande do Sul/University Foundation of Cardiology (IC/FUC), Princesa Isabel Avenue, 395, Porto Alegre, Rio Grande do Sul 90040-371, Brazil.; HCor Research Institute, Coracao Hospital (IP-HCor), Abílio Soares Street, 250, São Paulo 04004-05, Brazil.
المصدر: Nutrients [Nutrients] 2020 Mar 03; Vol. 12 (3). Date of Electronic Publication: 2020 Mar 03.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI Publishing
مواضيع طبية MeSH: Diet* , Nuts*, Antioxidants/*therapeutic use , Atherosclerosis/*prevention & control , Lipid Peroxidation/*drug effects , MAP Kinase Signaling System/*drug effects , Oxidative Stress/*drug effects, Animals ; Atherosclerosis/blood ; Biomarkers/blood ; Humans ; Polyphenols/therapeutic use ; Vitamin E/therapeutic use
مستخلص: Atherosclerosis is related to fat accumulation in the arterial walls and vascular stiffening, and results in acute coronary syndrome which is commonly associated with acute myocardial infarction. Oxidative stress participates in the pathogenesis of atherosclerosis. Thus, the inclusion of food sources of dietary antioxidants, such as different kinds of nuts, may improve biomarkers related to oxidative stress, contributing to a possible reduction in atherosclerosis progression. This article has briefly highlighted the interaction between oxidative stress, atherosclerosis, and cardiovascular disease, in addition to the effect of the consumption of different nuts and related dietary antioxidants-like polyphenols and vitamin E-on biomarkers of oxidative stress in primary and secondary cardiovascular prevention. Studies in vitro suggest that nuts may exert antioxidant effects by DNA repair mechanisms, lipid peroxidation prevention, modulation of the signaling pathways, and inhibition of the MAPK pathways through the suppression of NF-κB and activation of the Nrf2 pathways. Studies conducted in animal models showed the ability of dietary nuts in improving biomarkers of oxidative stress, such as oxLDL and GPx. However, clinical trials in humans have not been conclusive, especially with regards to the secondary prevention of cardiovascular disease.
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فهرسة مساهمة: Keywords: antioxidants; cardiovascular diseases; nuts; oxidative stress
المشرفين على المادة: 0 (Antioxidants)
0 (Biomarkers)
0 (Polyphenols)
1406-18-4 (Vitamin E)
تواريخ الأحداث: Date Created: 20200307 Date Completed: 20201204 Latest Revision: 20201214
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC7146201
DOI: 10.3390/nu12030682
PMID: 32138220
قاعدة البيانات: MEDLINE
الوصف
تدمد:2072-6643
DOI:10.3390/nu12030682