دورية أكاديمية
Atrial function in Fontan patients assessed by CMR: Relation with exercise capacity and long-term outcomes.
| العنوان: | Atrial function in Fontan patients assessed by CMR: Relation with exercise capacity and long-term outcomes. |
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| المؤلفون: | van der Ven JPG; Department of Pediatrics, Division of Cardiology, Erasmus Medical Centre - Sophia Children's Hospital, Rotterdam, the Netherlands; Netherlands Heart Institute, Utrecht, the Netherlands., Alsaied T; Department of Cardiology, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA, USA; Department of Cardiology, Cincinnati Children's Hospital, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Juggan S; Department of Cardiology, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Bossers SSM; Department of Pediatrics, Division of Cardiology, Erasmus Medical Centre - Sophia Children's Hospital, Rotterdam, the Netherlands., van den Bosch E; Department of Pediatrics, Division of Cardiology, Erasmus Medical Centre - Sophia Children's Hospital, Rotterdam, the Netherlands; Netherlands Heart Institute, Utrecht, the Netherlands., Kapusta L; Department of Pediatrics, Division of Cardiology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands; Pediatric Cardiology Unit, Tel-Aviv Sourasky Medical Center, Tel Aviv University Sackler School of Medicine, Tel Aviv, Israel., Kuipers IM; Department of Pediatrics, Division of Cardiology, Academic Medical Centre, Amsterdam, the Netherlands., Kroft LJM; Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands., Ten Harkel ADJ; Department of Pediatrics, Division of Cardiology, Leiden University Medical Centre, Leiden, the Netherlands., van Iperen GG; Department of Pediatrics, Division of Cardiology, University Medical Centre Utrecht - Wilhelmina Children's Hospital, Utrecht, the Netherlands., Rathod RH; Department of Cardiology, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Helbing WA; Department of Pediatrics, Division of Cardiology, Erasmus Medical Centre - Sophia Children's Hospital, Rotterdam, the Netherlands; Department of Radiology, Erasmus Medical Centre, Rotterdam, the Netherlands; Department of Pediatrics, Division of Cardiology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands. Electronic address: w.a.helbing@erasmusmc.nl. |
| المصدر: | International journal of cardiology [Int J Cardiol] 2020 Aug 01; Vol. 312, pp. 56-61. Date of Electronic Publication: 2020 Feb 24. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8200291 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1874-1754 (Electronic) Linking ISSN: 01675273 NLM ISO Abbreviation: Int J Cardiol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Amsterdam : Elsevier Original Publication: Amsterdam : Elsevier/North-Holland Biomedical Press, c1981- |
| مواضيع طبية MeSH: | Fontan Procedure* , Heart Defects, Congenital*/diagnostic imaging , Heart Defects, Congenital*/surgery, Atrial Function ; Child ; Exercise Tolerance ; Heart Ventricles ; Humans |
| مستخلص: | Objective: To assess the role of atrial function on exercise capacity and clinical events in Fontan patients. Design: We included 96 Fontan patients from 6 tertiary centers, aged 12.8 (IQR 10.1-15.6) years, who underwent cardiac magnetic resonance imaging and cardiopulmonary exercise testing within 12 months of each other from 2004 to 2017. Intra-atrial lateral tunnel (ILT) and extracardiac conduit (ECC) patients were matched 1:1 with regard to age, gender and dominant ventricle. The pulmonary venous atrium was manually segmented in all phases and slices. Atrial function was assessed by volume-time curves. Furthermore, atrial longitudinal and circumferential feature tracking strain was assessed. We determined the relation between atrial function and exercise capacity, assessed by peak oxygen uptake and VE/VCO Results: Atrial maximal and minimal volumes did not differ between ILT and ECC patients. ECC patients had higher reservoir function (21.1 [16.4-28.0]% vs 18.2 [10.9-22.2]%, p = .03), lower conduit function and lower total circumferential strain (13.8 ± 5.1% vs 18.0 ± 8.7%, p = .01), compared to ILT patients. Only for ECC patients, a better late peak circumferential strain rate predicted better VE/VCO Conclusions: ECC patients have higher atrial reservoir function and lower conduit function. Atrial function did not predict exercise capacity or events during follow-up. Competing Interests: Conflict of interest All authors declare no conflicts of interest. (Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.) |
| التعليقات: | Comment in: Int J Cardiol. 2020 Nov 15;319:67-68. (PMID: 32485193) |
| فهرسة مساهمة: | Keywords: Atrial function; CMR; Feature tracking strain; Fontan; Pediatrics; Univentricular heart disease |
| تواريخ الأحداث: | Date Created: 20200307 Date Completed: 20210514 Latest Revision: 20210514 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.ijcard.2020.02.060 |
| PMID: | 32139238 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1874-1754 |
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| DOI: | 10.1016/j.ijcard.2020.02.060 |