دورية أكاديمية
أعرض في EDS

Serum Clara cell secretory protein (CC-16) in non-smoking patients with obstructive sleep apnea.

التفاصيل البيبلوغرافية
العنوان: Serum Clara cell secretory protein (CC-16) in non-smoking patients with obstructive sleep apnea.
المؤلفون: Gulec Balbay E; Faculty of Medicine, Department of Chest Disease, Duzce University, Düzce, Turkey. egegulecbalbay@gmail.com., Ataoglu O; Faculty of Medicine, Department of Chest Disease, Duzce University, Düzce, Turkey., Ercelik M; Faculty of Medicine, Department of Chest Disease, Duzce University, Düzce, Turkey., Sahin IE; Faculty of Medicine, Department of Biochemistry, Duzce University, Düzce, Turkey., Admis O; Department of Biochemistry, Erzincan University Mengücek Gazi Training and Research Hospital, Erzincan, Turkey., Arbak PM; Faculty of Medicine, Department of Chest Disease, Duzce University, Düzce, Turkey.
المصدر: Sleep & breathing = Schlaf & Atmung [Sleep Breath] 2020 Dec; Vol. 24 (4), pp. 1607-1612. Date of Electronic Publication: 2020 Mar 06.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer Country of Publication: Germany NLM ID: 9804161 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1709 (Electronic) Linking ISSN: 15209512 NLM ISO Abbreviation: Sleep Breath Subsets: MEDLINE
أسماء مطبوعة: Publication: 2005- : Heidelberg ; New York : Springer
Original Publication: Titisee-Neustadt, Germany : Druckbild GmbH,
مواضيع طبية MeSH: Sleep Apnea, Obstructive/*blood , Uteroglobin/*blood, Adult ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Severity of Illness Index ; Sleep Apnea, Obstructive/epidemiology
مستخلص: Objective: This study aimed to determine the association between the severity of obstructive sleep apnea (OSA) and serum Clara cell protein (CC16) levels in non-smoking patients with OSA.
Methods: This prospective study included non-smoking patients who presented with sleep-related disturbances and underwent polysomnography (PSG). The serum CC16 level was measured and its relationship to PSG parameters was investigated.
Results: The study included 128 patients (83 men) with a mean age of 48.4 ± 11.9. OSA was detected in 66 men (70%) and 29 women (30%) (p = 0.051). The severity of OSA was mild in 32 (25%), moderate in 28 (22%), and severe in 35 (27%) of the patients. There was no significant difference in CC16 levels between the OSA group (1746 ± 1006) and the OSA negative group (1721 ± 1201, p = 0.91) levels. There was no significant difference between the CC16 levels of the each four groups. Mean serum CC16 levels were significantly lower in OSA negative men than OSA positive men (777 vs 1462, p = 0.005). No significant difference was observed in CC16 values according to OSA severity in women.
Conclusion: The serum CC16 level does not differ between non-smoking OSA patients and OSA negative patients.
فهرسة مساهمة: Keywords: Clara cell protein; Obstructive sleep apnea syndrome
المشرفين على المادة: 9060-09-7 (Uteroglobin)
تواريخ الأحداث: Date Created: 20200308 Date Completed: 20211119 Latest Revision: 20211119
رمز التحديث: 20240628
DOI: 10.1007/s11325-020-02042-z
PMID: 32144590
قاعدة البيانات: MEDLINE
الوصف
تدمد:1522-1709
DOI:10.1007/s11325-020-02042-z