دورية أكاديمية
Genome-wide analysis reveals genetic diversity, linkage disequilibrium, and selection for milk production traits in Chinese buffalo breeds.
| العنوان: | Genome-wide analysis reveals genetic diversity, linkage disequilibrium, and selection for milk production traits in Chinese buffalo breeds. |
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| المؤلفون: | Lu XR; Key Laboratory of Buffalo Genetics, Breeding and Reproduction Technology, Buffalo Research Institute, Chinese Academy of Agricultural Sciences, Nanning 530001, China., Duan AQ; Key Laboratory of Buffalo Genetics, Breeding and Reproduction Technology, Buffalo Research Institute, Chinese Academy of Agricultural Sciences, Nanning 530001, China., Li WQ; BGI Genomics, BGI-Shenzhen, Shenzhen 518083, China., Abdel-Shafy H; Department of Animal Production, Faculty of Agriculture, Cairo University, 12613 Giza, Egypt., Rushdi HE; Department of Animal Production, Faculty of Agriculture, Cairo University, 12613 Giza, Egypt., Liang SS; Key Laboratory of Buffalo Genetics, Breeding and Reproduction Technology, Buffalo Research Institute, Chinese Academy of Agricultural Sciences, Nanning 530001, China., Ma XY; Key Laboratory of Buffalo Genetics, Breeding and Reproduction Technology, Buffalo Research Institute, Chinese Academy of Agricultural Sciences, Nanning 530001, China., Liang XW; Key Laboratory of Buffalo Genetics, Breeding and Reproduction Technology, Buffalo Research Institute, Chinese Academy of Agricultural Sciences, Nanning 530001, China., Deng TX; Key Laboratory of Buffalo Genetics, Breeding and Reproduction Technology, Buffalo Research Institute, Chinese Academy of Agricultural Sciences, Nanning 530001, China. Electronic address: dtx282000@163.com. |
| المصدر: | Journal of dairy science [J Dairy Sci] 2020 May; Vol. 103 (5), pp. 4545-4556. Date of Electronic Publication: 2020 Mar 05. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Dairy Science Association Country of Publication: United States NLM ID: 2985126R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-3198 (Electronic) Linking ISSN: 00220302 NLM ISO Abbreviation: J Dairy Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Champaign, IL : American Dairy Science Association Original Publication: Lancaster, Pa. [etc.] |
| مواضيع طبية MeSH: | Genetic Variation* , Genome*, Buffaloes/*genetics, Animals ; Breeding ; China ; Female ; Genetics, Population ; Genomics ; Heterozygote ; Homozygote ; Inbreeding ; Linkage Disequilibrium ; Milk ; Phenotype |
| مستخلص: | The water buffalo is an important dual-purpose livestock that is widespread throughout central and southern China. However, there has been no characterization of the population genetics of Chinese buffalo. Using an Axiom buffalo genotyping array (Thermo Fisher Scientific, Wilmington, DE), we analyzed the genetic diversity, linkage disequilibrium pattern, and signature of selection in 176 Chinese buffaloes from 13 breeds. A total of 35,547 SNP passed quality control and were used for further analyses. Population genetic analysis revealed a clear separation between swamp and river types. Ten Chinese indigenous breeds were clustered into the swamp group, the Murrah and Nili-Ravi breeds were clustered into the river group, and the crossbred breed was closer to the river group. Genetic diversity analysis showed that the swamp group had a lower average expected heterozygosity. Linkage disequilibrium decay distance was much shorter in the swamp group compared with the river group, with an average square of correlation coefficient value of 0.2 of approximately 50 kb. Analysis of runs of homozygosity indicated extensive remote and recent inbreeding within swamp and river groups, respectively. Moreover, one genomic region under selection was detected between the river and swamp groups. Our findings contribute to our understanding of the characterization of population genetics in Chinese buffaloes, which in turn may be used in buffalo breeding programs. (Copyright © 2020 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: buffalo; linkage disequilibrium; population analysis; selection signature |
| تواريخ الأحداث: | Date Created: 20200310 Date Completed: 20200923 Latest Revision: 20200923 |
| رمز التحديث: | 20231215 |
| DOI: | 10.3168/jds.2019-17364 |
| PMID: | 32147265 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1525-3198 |
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| DOI: | 10.3168/jds.2019-17364 |