دورية أكاديمية
أعرض في EDS

Vitamin C and E supplementation does not affect heat shock proteins or endogenous antioxidants in trained skeletal muscles during 12 weeks of strength training.

التفاصيل البيبلوغرافية
العنوان: Vitamin C and E supplementation does not affect heat shock proteins or endogenous antioxidants in trained skeletal muscles during 12 weeks of strength training.
المؤلفون: Cumming KT; 1Department of Physical Performance, Norwegian School of Sport Sciences, Oslo, Norway., Raastad T; 1Department of Physical Performance, Norwegian School of Sport Sciences, Oslo, Norway., Sørstrøm A; 1Department of Physical Performance, Norwegian School of Sport Sciences, Oslo, Norway., Paronetto MP; 2Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy., Mercatelli N; 2Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy., Ugelstad I; 1Department of Physical Performance, Norwegian School of Sport Sciences, Oslo, Norway., Caporossi D; 2Department of Movement, Human and Health Sciences, University of Rome 'Foro Italico', Rome, Italy., Paulsen G; 1Department of Physical Performance, Norwegian School of Sport Sciences, Oslo, Norway.; Norwegian Olympic Sports Center, Oslo, Norway.
المصدر: BMC nutrition [BMC Nutr] 2017 Aug 17; Vol. 3, pp. 70. Date of Electronic Publication: 2017 Aug 17 (Print Publication: 2017).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101672434 Publication Model: eCollection Cited Medium: Internet ISSN: 2055-0928 (Electronic) Linking ISSN: 20550928 NLM ISO Abbreviation: BMC Nutr Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2015]-
مستخلص: Background: Supplementation with large doses of antioxidants, such as vitamin C and E, has been shown to blunt some adaptations to endurance training. The effects of antioxidant supplementation on adaptations to strength training is sparsely studied. Herein we investigated the effects of vitamin C and E supplementation on acute stress responses to exercise and adaptation to traditional heavy load strength training.
Methods: In a double blind placebo-controlled design, twenty-eight, young, trained males and females were randomly assigned to receive either vitamin C and E (C: 1000 mg, E: 235 mg, per day) or placebo supplements, and underwent strength training for 10 weeks. After five weeks, a subgroup conducted a strength training session to investigate acute stress responses. Muscle samples were obtained to investigate changes in stress responses and in proteins and mRNA related to the heat shock proteins (HSPs) or antioxidant enzymes.
Results: The acute responses to the exercise session revealed activation of the NFκB pathway indicated by degradation of IκBα in both groups. Vitamin C and E supplementation had, however, no effects on the acute stress responses. Furthermore, ten weeks of strength training did not change muscle αB-crystallin, HSP27, HSP70, GPx1 or mnSOD levels, with no influence of supplementation.
Conclusions: Our results showed that although vitamin C and E supplementation has been shown to interfere with training adaptations, it did not affect acute stress responses or long-term training adaptations in the HSPs or antioxidant enzymes in this study.
Competing Interests: Competing interestsThe authors declare that they have no competing interests.
(© The Author(s). 2017.)
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فهرسة مساهمة: Keywords: Gene expression; Resistance training; Stress proteins
تواريخ الأحداث: Date Created: 20200311 Latest Revision: 20220413
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC7050865
DOI: 10.1186/s40795-017-0185-8
PMID: 32153849
قاعدة البيانات: MEDLINE
الوصف
تدمد:2055-0928
DOI:10.1186/s40795-017-0185-8