دورية أكاديمية
أعرض في EDS

Role of advanced left ventricular imaging in adults with aortic stenosis.

التفاصيل البيبلوغرافية
العنوان: Role of advanced left ventricular imaging in adults with aortic stenosis.
المؤلفون: Calin A; Department of Cardiology, Euroecolab, University of Medicine and Pharmacy 'Carol Davila', Bucharest, Romania.; Department of Cardiology, Emergency Institute for Cardiovascular Diseases 'Prof Dr C C Iliescu', Bucharest, Romania., Mateescu AD; Department of Cardiology, Euroecolab, University of Medicine and Pharmacy 'Carol Davila', Bucharest, Romania.; Department of Cardiology, Emergency Institute for Cardiovascular Diseases 'Prof Dr C C Iliescu', Bucharest, Romania., Popescu AC; Department of Cardiology, Euroecolab, University of Medicine and Pharmacy 'Carol Davila', Bucharest, Romania.; Department of Cardiology, Emergency University Hospital Elias, Bucharest, Romania., Bing R; BHF Centre for Cardiovascular Science, The University of Edinburgh, Edinburgh, EH16 4SB, United Kingdom., Dweck MR; BHF Centre for Cardiovascular Science, The University of Edinburgh, Edinburgh, EH16 4SB, United Kingdom., Popescu BA; Department of Cardiology, Euroecolab, University of Medicine and Pharmacy 'Carol Davila', Bucharest, Romania bogdan.a.popescu@gmail.com.; Department of Cardiology, Emergency Institute for Cardiovascular Diseases 'Prof Dr C C Iliescu', Bucharest, Romania.
المصدر: Heart (British Cardiac Society) [Heart] 2020 Jul; Vol. 106 (13), pp. 962-969. Date of Electronic Publication: 2020 Mar 16.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review
اللغة: English
بيانات الدورية: Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 9602087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-201X (Electronic) Linking ISSN: 13556037 NLM ISO Abbreviation: Heart Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BMJ Pub. Group, c1996-
مواضيع طبية MeSH: Echocardiography* , Magnetic Resonance Imaging* , Stroke Volume* , Ventricular Function, Left* , Ventricular Remodeling*, Aortic Valve Stenosis/*diagnostic imaging , Heart Ventricles/*diagnostic imaging , Ventricular Dysfunction, Left/*diagnostic imaging, Aortic Valve Stenosis/pathology ; Aortic Valve Stenosis/physiopathology ; Aortic Valve Stenosis/therapy ; Clinical Decision-Making ; Fibrosis ; Heart Ventricles/physiopathology ; Humans ; Myocardium/pathology ; Predictive Value of Tests ; Prognosis ; Ventricular Dysfunction, Left/pathology ; Ventricular Dysfunction, Left/physiopathology ; Ventricular Dysfunction, Left/therapy
مستخلص: This review focuses on the available data regarding the utility of advanced left ventricular (LV) imaging in aortic stenosis (AS) and its potential impact for optimising the timing of aortic valve replacement. Ejection fraction is currently the only LV parameter recommended to guide intervention in AS. The cut-off value of 50%, recommended for decision-making in asymptomatic patients with AS, is currently under debate. Several imaging parameters have emerged as predictors of disease progression and clinical outcomes in this setting. Global longitudinal LV strain by speckle tracking echocardiography is useful for risk stratification of asymptomatic patients with severe AS and preserved LV ejection fraction. Its prognostic value was demonstrated in these patients, but further work is required to define the best thresholds to aid the decision-making process. The assessment of myocardial fibrosis is the most studied application of cardiac magnetic resonance in AS. The detection of replacement fibrosis by late gadolinium enhancement offers incremental prognostic information in these patients. Clinical implementation of this technique to optimise the timing of aortic valve intervention in asymptomatic patients is currently tested in a randomised trial. The use of T1 mapping techniques can provide an assessment of interstitial myocardial fibrosis and represents an expanding field of interest. However, convincing data in patients with AS is still lacking. All these imaging parameters have substantial potential to influence the management decision in patients with AS in the future, but data from randomised clinical trials are awaited to define their utility in daily practice.
Competing Interests: Competing interests: BAP has received research support and lecture honoraria from General Electric Healthcare.
(© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
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معلومات مُعتمدة: FS/14/78/31020 United Kingdom BHF_ British Heart Foundation; PG/19/40/34422 United Kingdom BHF_ British Heart Foundation
فهرسة مساهمة: Keywords: advanced cardiac imaging; aortic stenosis; cardiac magnetic resonance (CMR) imaging; echocardiography
تواريخ الأحداث: Date Created: 20200318 Date Completed: 20210628 Latest Revision: 20211214
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC7306876
DOI: 10.1136/heartjnl-2019-315211
PMID: 32179586
قاعدة البيانات: MEDLINE
الوصف
تدمد:1468-201X
DOI:10.1136/heartjnl-2019-315211