دورية أكاديمية
Immunological roles of intestinal mesenchymal cells.
العنوان: | Immunological roles of intestinal mesenchymal cells. |
---|---|
المؤلفون: | Thomson CA; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Nibbs RJ; Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, UK., McCoy KD; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Mowat AM; Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, UK. |
المصدر: | Immunology [Immunology] 2020 Aug; Vol. 160 (4), pp. 313-324. Date of Electronic Publication: 2020 Apr 20. |
نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't; Review |
اللغة: | English |
بيانات الدورية: | Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 0374672 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2567 (Electronic) Linking ISSN: 00192805 NLM ISO Abbreviation: Immunology Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Oxford : Blackwell Scientific Publications |
مواضيع طبية MeSH: | Inflammation/*immunology , Inflammatory Bowel Diseases/*immunology , Intestinal Mucosa/*immunology , Intestines/*immunology , Mesenchymal Stem Cells/*immunology, Animals ; Homeostasis ; Humans ; Immune Tolerance ; Immunity |
مستخلص: | The intestine is continuously exposed to an enormous variety and quantity of antigens and innate immune stimuli derived from both pathogens and harmless materials, such as food and commensal bacteria. Accordingly, the intestinal immune system is uniquely adapted to ensure appropriate responses to the different kinds of challenge; maintaining tolerance to harmless antigens in the steady-state, whilst remaining poised to deal with potential pathogens. To accomplish this, leucocytes of the intestinal immune system have to adapt to a constantly changing environment and interact with many different non-leucocytic intestinal cell types, including epithelial and endothelial cells, neurons, and a heterogenous network of intestinal mesenchymal cells (iMC). These interactions are intricately involved in the generation of protective immunity, the elaboration of inflammatory responses, and the development of inflammatory conditions, such as inflammatory bowel diseases. Here we discuss recent insights into the immunological functions of iMC under homeostatic and inflammatory conditions, focusing particularly on iMC in the mucosa and submucosa, and highlighting how an appreciation of the immunology of iMC may help understand the pathogenesis and treatment of disease. (© 2020 John Wiley & Sons Ltd.) |
References: | J Gastroenterol. 2005 May;40(5):483-9. (PMID: 15942713) Inflamm Bowel Dis. 2013 Dec;19(13):2829-39. (PMID: 24051933) J Immunol. 2018 Jul 1;201(1):215-229. (PMID: 29760193) Mucosal Immunol. 2016 Jan;9(1):183-93. (PMID: 26129652) J Gastroenterol Hepatol. 2005 Apr;20(4):619-27. (PMID: 15836713) J Gastroenterol. 2010 Oct;45(10):999-1007. (PMID: 20405148) Cell Rep. 2016 May 24;15(8):1743-56. (PMID: 27184849) Immunity. 2011 May 27;34(5):769-80. (PMID: 21565531) Fibrogenesis Tissue Repair. 2013 Jul 08;6(1):13. (PMID: 23834907) Nat Rev Gastroenterol Hepatol. 2009 Apr;6(4):228-35. (PMID: 19347014) J Clin Invest. 2002 Oct;110(8):1113-21. (PMID: 12393847) Nat Immunol. 2014 Oct;15(10):929-937. (PMID: 25151491) Mucosal Immunol. 2014 Jul;7(4):948-57. (PMID: 24399151) Immunity. 2015 Jul 21;43(1):187-99. (PMID: 26200014) Sci Immunol. 2019 Dec 20;4(42):. (PMID: 31862865) Science. 2006 Nov 17;314(5802):1157-60. (PMID: 17110582) Front Immunol. 2018 May 30;9:1125. (PMID: 29910803) J Biol Chem. 2000 Jun 2;275(22):16709-16. (PMID: 10828062) J Leukoc Biol. 2019 Mar;105(3):507-518. (PMID: 30576006) J Immunol. 2007 Sep 1;179(5):2824-31. (PMID: 17709496) Front Microbiol. 2019 Jan 14;9:3225. (PMID: 30692968) Dig Dis Sci. 2009 Feb;54(2):238-45. (PMID: 18629644) Gastroenterology. 2010 Oct;139(4):1277-88. (PMID: 20600022) Am J Physiol Gastrointest Liver Physiol. 2005 Jul;289(1):G116-28. (PMID: 15778431) Br J Nutr. 2010 Aug;104(4):503-12. (PMID: 20338073) Gastroenterology. 2003 Jun;124(7):1866-78. (PMID: 12806620) Gastroenterology. 2003 Nov;125(5):1341-54. (PMID: 14598250) J Interferon Cytokine Res. 2001 Jan;21(1):21-30. (PMID: 11177577) J Interferon Cytokine Res. 2015 Aug;35(8):634-40. (PMID: 26101946) J Exp Med. 2004 Feb 2;199(3):411-6. (PMID: 14744993) Scand J Gastroenterol. 2001 Apr;36(4):389-98. (PMID: 11336164) Immunol Rev. 2004 Dec;202:49-66. (PMID: 15546385) Cell Rep. 2019 Mar 26;26(13):3698-3708.e5. (PMID: 30917322) J Immunol. 2000 Mar 15;164(6):2851-6. (PMID: 10706668) J Biol Chem. 2005 Oct 28;280(43):36099-109. (PMID: 16141211) J Immunol. 2014 Sep 1;193(5):2218-29. (PMID: 25070848) J Immunol. 2006 Nov 1;177(9):5968-79. (PMID: 17056521) Nat Immunol. 2014 Jul;15(7):623-30. (PMID: 24813163) Inflamm Bowel Dis. 2001 Feb;7(1):16-26. (PMID: 11233656) Clin Exp Immunol. 2003 Oct;134(1):120-6. (PMID: 12974764) J Immunol. 2015 Jun 15;194(12):5980-9. (PMID: 25964486) Gastroenterology. 1990 Aug;99(2):447-53. (PMID: 2365193) J Immunol. 2009 Feb 15;182(4):2102-12. (PMID: 19201863) Cell. 2018 Oct 4;175(2):372-386.e17. (PMID: 30270042) Science. 2014 Mar 28;343(6178):1249288. (PMID: 24625929) Inflamm Bowel Dis. 2001 Aug;7(3):226-36. (PMID: 11515849) PLoS One. 2012;7(12):e52332. (PMID: 23300643) Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E506-E513. (PMID: 28074039) Am J Pathol. 2010 Dec;177(6):2804-15. (PMID: 21037074) Am J Pathol. 2012 Feb;180(2):636-49. (PMID: 22138299) Nat Rev Rheumatol. 2018 Dec;14(12):714-726. (PMID: 30420750) Arthritis Res Ther. 2017 Feb 10;19(1):35. (PMID: 28187781) J Leukoc Biol. 2003 Sep;74(3):448-55. (PMID: 12949249) Mucosal Immunol. 2009 Jul;2(4):340-50. (PMID: 19387433) Immunol Rev. 2019 May;289(1):31-41. (PMID: 30977192) Cell. 2019 Nov 14;179(5):1160-1176.e24. (PMID: 31730855) Cytokine Growth Factor Rev. 1997 Sep;8(3):171-9. (PMID: 9462483) Am J Gastroenterol. 2006 Apr;101(4):793-7. (PMID: 16635225) Acta Pol Pharm. 2010 Nov-Dec;67(6):690-5. (PMID: 21229889) Nature. 2010 Jan 28;463(7280):540-4. (PMID: 20023630) Gastroenterology. 2008 Oct;135(4):1228-1237, 1237.e1-2. (PMID: 18760278) Proc Natl Acad Sci U S A. 1986 Jun;83(12):4167-71. (PMID: 2424019) Gastroenterology. 2011 Jun;140(7):2019-30. (PMID: 21376048) Am J Physiol Gastrointest Liver Physiol. 2013 May 1;304(9):G823-34. (PMID: 23429582) Clin Epigenetics. 2016 Mar 12;8:30. (PMID: 26973718) Gut. 2003 Oct;52(10):1442-7. (PMID: 12970137) J Immunol. 2014 Aug 1;193(3):999-1005. (PMID: 25049430) Mucosal Immunol. 2015 Jan;8(1):141-51. (PMID: 24938743) Mucosal Immunol. 2017 Jul;10(4):912-923. (PMID: 27966552) Am J Physiol Gastrointest Liver Physiol. 2002 Jun;282(6):G1035-44. (PMID: 12016129) Nature. 2007 Jun 7;447(7145):661-78. (PMID: 17554300) Am J Physiol Gastrointest Liver Physiol. 2003 Sep;285(3):G529-38. (PMID: 12760902) Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):E4658-67. (PMID: 25316791) Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):8017-22. (PMID: 20385815) Mucosal Immunol. 2014 Nov;7(6):1492-503. (PMID: 24850426) Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1885-90. (PMID: 12571364) Am J Physiol. 1999 Aug;277(2):C183-201. (PMID: 10444394) J Interferon Cytokine Res. 2015 May;35(5):340-50. (PMID: 25760898) Eur J Immunol. 2006 Jul;36(7):1904-16. (PMID: 16791897) Science. 2005 Jun 3;308(5727):1463-5. (PMID: 15933199) Inflamm Bowel Dis. 2015 Oct;21(10):2429-40. (PMID: 26218140) Scand J Gastroenterol. 2002 Mar;37(3):317-24. (PMID: 11916194) Am J Gastroenterol. 2004 Feb;99(2):335-40. (PMID: 15046226) Arthritis Rheumatol. 2015 Jan;67(1):86-95. (PMID: 25199798) J Cell Physiol. 2012 Sep;227(9):3291-300. (PMID: 22170005) Gastroenterology. 2017 Apr;152(5):964-979. (PMID: 28111227) Endocrinology. 1992 Oct;131(4):1703-10. (PMID: 1382959) PLoS One. 2018 Dec 27;13(12):e0209656. (PMID: 30589872) Am J Physiol Gastrointest Liver Physiol. 2002 Sep;283(3):G809-18. (PMID: 12181198) J Leukoc Biol. 2000 Feb;67(2):149-59. (PMID: 10670574) Immunity. 2014 Apr 17;40(4):530-41. (PMID: 24726878) J Immunol. 2016 Apr 15;196(8):3341-53. (PMID: 26976955) PLoS One. 2009;4(3):e4719. (PMID: 19262684) J Inflamm (Lond). 2016 Jan 05;13:1. (PMID: 26733763) Am J Physiol Gastrointest Liver Physiol. 2009 Mar;296(3):G601-11. (PMID: 19136385) J Crohns Colitis. 2017 Jan;11(1):92-104. (PMID: 27364949) Nat Rev Immunol. 2008 Jun;8(6):421-34. (PMID: 18483500) Gut. 2017 May;66(5):823-838. (PMID: 26783184) Nature. 2019 Jun;570(7760):246-251. (PMID: 31142839) Aliment Pharmacol Ther. 2002 Mar;16(3):399-406. (PMID: 11876692) J Immunol. 2009 Jan 1;182(1):507-14. (PMID: 19109182) Mucosal Immunol. 2018 Sep;11(5):1466-1476. (PMID: 29988118) Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6347-52. (PMID: 17404233) Growth Factors. 2002 Jun;20(2):81-91. (PMID: 12148566) Immunity. 2005 Nov;23(5):479-90. (PMID: 16286016) Inflamm Bowel Dis. 2011 Jan;17(1):193-201. (PMID: 20848532) J Immunol. 2006 Jan 15;176(2):803-10. (PMID: 16393963) Gut. 2009 Jun;58(6):777-89. (PMID: 19201776) World J Gastroenterol. 2009 Mar 28;15(12):1431-42. (PMID: 19322915) Cell Rep. 2019 Jan 15;26(3):536-545.e4. (PMID: 30650348) |
معلومات مُعتمدة: | 201903PJT-420305 Canada CIHR; JDRF 2-SRA-2018-547-S-B United States JDRF Juvenile Diabetes Research Foundation; United Kingdom MRC_ Medical Research Council |
فهرسة مساهمة: | Keywords: homeostasis; immune response; inflammation; intestine; mesenchymal stromal cell |
تواريخ الأحداث: | Date Created: 20200318 Date Completed: 20210526 Latest Revision: 20210802 |
رمز التحديث: | 20221213 |
مُعرف محوري في PubMed: | PMC7370112 |
DOI: | 10.1111/imm.13191 |
PMID: | 32181492 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1365-2567 |
---|---|
DOI: | 10.1111/imm.13191 |