دورية أكاديمية
أعرض في EDS

Sex-Specific Effects of Dietary Methionine Restriction on the Intestinal Microbiome.

التفاصيل البيبلوغرافية
العنوان: Sex-Specific Effects of Dietary Methionine Restriction on the Intestinal Microbiome.
المؤلفون: Wallis KF; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA., Melnyk SB; Arkansas Children's Research Institute, Little Rock, AR 72202, USA., Miousse IR; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
المصدر: Nutrients [Nutrients] 2020 Mar 16; Vol. 12 (3). Date of Electronic Publication: 2020 Mar 16.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI Publishing
مواضيع طبية MeSH: Bacteria*/classification , Bacteria*/growth & development , Gastrointestinal Microbiome* , Sex Characteristics*, Methionine/*deficiency, Animals ; Female ; Male ; Mice ; Mice, Inbred C57BL
مستخلص: Dietary methionine restriction is associated with improved health outcomes and an increase in lifespan in animal models. We have previously shown that an increase in dietary methionine induces alteration in the intestinal microbiome. The composition of the intestinal microbiota is a determinant of health and we, therefore, hypothesized that dietary methionine restriction would also induce changes in the murine microbiome. After one month on a methionine-restricted diet, five-month-old male and female C57BL/6 mice had decreased levels of serum methionine, without changes in body weight. We identified a decrease in the hepatic methylation status of animals fed a methionine-restricted diet compared to controls. This decrease was not associated with changes in DNA or protein methylation in the liver. In males, we saw an increase in families Bacteroidaceae and Verrucoccaceae (mostly A. mucinophila ) and a decrease in Rumminococcaceae in animals fed a methionine-restricted diet compared to controls. In females, Bacteroidales family S24-7 was increased two-fold, while families Bacteroidaceae , Verrucoccaceae, Rumminococcaceae, and Rikenellaceae were decreased compared to controls. In summary, feeding a methionine-restricted diet for one month was associated with significant and sex-specific changes in the intestinal microbiome.
References: J Nutr. 1993 Feb;123(2):269-74. (PMID: 8429371)
Gut Microbes. 2019;10(3):358-366. (PMID: 30373468)
Cell Host Microbe. 2008 Apr 17;3(4):213-23. (PMID: 18407065)
Carcinogenesis. 2018 Sep 21;39(9):1117-1126. (PMID: 29939201)
Exp Gerontol. 2017 Feb;88:1-8. (PMID: 27940170)
Science. 2018 Jan 5;359(6371):91-97. (PMID: 29097494)
Microbiology. 2017 May;163(5):646-648. (PMID: 28530168)
Nat Rev Endocrinol. 2020 Jan;16(1):59-66. (PMID: 31728051)
Anticancer Res. 2009 Dec;29(12):5235-40. (PMID: 20044642)
Front Endocrinol (Lausanne). 2018 Aug 06;9:443. (PMID: 30127768)
Front Microbiol. 2017 Apr 11;8:608. (PMID: 28443082)
Toxicol Sci. 2015 Dec;148(2):473-87. (PMID: 26342214)
Med Hypotheses. 2009 Feb;72(2):125-8. (PMID: 18789600)
PLoS One. 2015 Apr 15;10(4):e0124599. (PMID: 25874569)
Front Cell Dev Biol. 2019 Nov 28;7:301. (PMID: 31850341)
Gut Microbes. 2016 Jul 3;7(4):313-322. (PMID: 27355107)
Nat Commun. 2018 May 16;9(1):1955. (PMID: 29769529)
Ann N Y Acad Sci. 2016 Jan;1363:59-67. (PMID: 26646941)
Sci Rep. 2015 Mar 06;5:8886. (PMID: 25744495)
Aging Cell. 2005 Jun;4(3):119-25. (PMID: 15924568)
Clin Nutr. 2014 Dec;33(6):929-36. (PMID: 24814383)
BMJ. 2017 Mar 15;356:j831. (PMID: 28298355)
Microbiome. 2016 Jul 07;4(1):36. (PMID: 27388460)
BMC Microbiol. 2017 May 22;17(1):120. (PMID: 28532414)
Nat Genet. 2020 Mar;52(3):306-319. (PMID: 32024998)
J Gerontol A Biol Sci Med Sci. 2009 Jul;64(7):711-22. (PMID: 19414512)
Mol Med Rep. 2016 Jul;14(1):289-300. (PMID: 27175774)
Obesity (Silver Spring). 2013 Dec;21(12):E607-15. (PMID: 23526699)
Cell Metab. 2020 Feb 4;31(2):250-266.e9. (PMID: 32023446)
Lancet Planet Health. 2018 Oct;2(10):e451-e461. (PMID: 30318102)
Science. 2018 Jan 5;359(6371):104-108. (PMID: 29302014)
Crit Rev Food Sci Nutr. 2017 Nov 22;57(17):3640-3649. (PMID: 26853923)
Science. 2018 Jan 5;359(6371):97-103. (PMID: 29097493)
Nature. 2019 Aug;572(7769):397-401. (PMID: 31367041)
Genes Nutr. 2017 Sep 6;12:22. (PMID: 28904640)
Front Genet. 2019 Jul 03;10:613. (PMID: 31333715)
Am J Clin Nutr. 2003 Aug;78(2):250-8. (PMID: 12885705)
J Geriatr Cardiol. 2017 May;14(5):342-354. (PMID: 28630614)
Appetite. 2017 Sep 1;116:456-463. (PMID: 28551111)
Br J Nutr. 2012 Aug;108 Suppl 2:S105-12. (PMID: 23107521)
Cell Host Microbe. 2018 Jun 13;23(6):705-715. (PMID: 29902436)
Nat Commun. 2014 Apr 07;5:3592. (PMID: 24710037)
Int J Med Microbiol. 2016 Aug;306(5):343-355. (PMID: 27053239)
معلومات مُعتمدة: KL2 TR003108 United States TR NCATS NIH HHS; 1KL2TR003108-01 United States NH NIH HHS
فهرسة مساهمة: Keywords: diet; methionine; methylation; microbiome
المشرفين على المادة: AE28F7PNPL (Methionine)
تواريخ الأحداث: Date Created: 20200320 Date Completed: 20201209 Latest Revision: 20201214
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC7146121
DOI: 10.3390/nu12030781
PMID: 32187981
قاعدة البيانات: MEDLINE
الوصف
تدمد:2072-6643
DOI:10.3390/nu12030781