دورية أكاديمية
The predictive value of the platelet volume parameters in evaluation of varicocelectomy outcome in infertile patients.
| العنوان: | The predictive value of the platelet volume parameters in evaluation of varicocelectomy outcome in infertile patients. |
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| المؤلفون: | Ghanem MA; Department of Urology, Jazan University, KSA, Jazan, Saudi Arabia.; Menoufia University, Shebin El-kom, Egypt., Adawi EA; Department of Urology, Jazan University, KSA, Jazan, Saudi Arabia., Hakami NA; Department of General Surgery, Jazan University, KSA, Jazan, Saudi Arabia., Ghanem AM; Kasr Al-Ainy Faculty of Medicine, Cairo University, Cairo, Egypt., Ghanem HA; Clinical Pathology Department, Mansoura University, Mansoura, Egypt. |
| المصدر: | Andrologia [Andrologia] 2020 Jun; Vol. 52 (5), pp. e13574. Date of Electronic Publication: 2020 Mar 20. |
| نوع المنشور: | Journal Article; Observational Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Blackwell Pub Country of Publication: Germany NLM ID: 0423506 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-0272 (Electronic) Linking ISSN: 03034569 NLM ISO Abbreviation: Andrologia Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Original Publication: Berlin, Grosse |
| مواضيع طبية MeSH: | Mean Platelet Volume*, Infertility, Male/*surgery , Urologic Surgical Procedures, Male/*methods , Varicocele/*surgery , Vascular Surgical Procedures/*methods, Adolescent ; Adult ; Biomarkers/blood ; Case-Control Studies ; Feasibility Studies ; Follow-Up Studies ; Healthy Volunteers ; Humans ; Infertility, Male/blood ; Infertility, Male/diagnosis ; Infertility, Male/etiology ; Male ; Platelet Count ; Postoperative Period ; Predictive Value of Tests ; Preoperative Period ; Prognosis ; Recurrence ; Semen Analysis ; Spermatic Cord/blood supply ; Spermatic Cord/surgery ; Testosterone/blood ; Treatment Outcome ; Varicocele/blood ; Varicocele/complications ; Young Adult |
| مستخلص: | The aim of this study was to evaluate the role of platelet count (PLT) and platelet volume indices (PVI) such as mean platelet volume (MPV), platelet distribution width (PDW) and plateletcrit (PCT) as a clinical biomarker in 64 infertile males with varicocele and 45 controls. In addition, semen parameters, serum total testosterone, FSH and testicular volume were measured before and at 6 months after varicocelectomy. The mean PLT, MPV, PDW and PCT were 231 ± 42 × 103/µl, 9.6 ± 1.8 fl, 16.2 ± 2.5 fl and 0.18% in the patient group respectively. When the patient and control groups were compared, there was a significant increase in mean MPV, PDW and PCT (p < .0001), while platelet count was lower in patients than control group, but with no significant relationship. MPV had a significant negative correlation with total testosterone (p < .03). No significant correlations were found between PVI and testicular volume. After follow-up of 37.1 ± 1.9 months, a significant negative correlation was found between the preoperative MPV and varicocelectomy outcome in terms of semen values (p < .007). So, the increase in MPV and low total testosterone in men with varicocele may be a feature of high risk of infertility. (© 2020 Blackwell Verlag GmbH.) |
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| فهرسة مساهمة: | Keywords: infertility; mean platelet volume; platelets count; semen parameters; varicocele |
| المشرفين على المادة: | 0 (Biomarkers) 3XMK78S47O (Testosterone) |
| تواريخ الأحداث: | Date Created: 20200321 Date Completed: 20210201 Latest Revision: 20210201 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1111/and.13574 |
| PMID: | 32196717 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1439-0272 |
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| DOI: | 10.1111/and.13574 |