دورية أكاديمية
Vitamin D Deficiency and Radiological Findings in Adult Non-Cystic Fibrosis Bronchiectasis.
العنوان: | Vitamin D Deficiency and Radiological Findings in Adult Non-Cystic Fibrosis Bronchiectasis. |
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المؤلفون: | Niksarlıoğlu EY; Department of Chest Diseases, Health Science University, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Turkey., Kılıç L; Department of Chest Diseases, Health Science University, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Turkey., Bilici D; Department of Chest Diseases, Giresun Dr. Ali Menekşe Chest Diseases Hospital, Giresun, Turkey., Yiğitbaş B; Department of Chest Diseases, Health Science University, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Turkey., Uysal MA; Department of Chest Diseases, Health Science University, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Turkey., Çamsarı G; Department of Chest Diseases, Health Science University, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Turkey. |
المصدر: | Turkish thoracic journal [Turk Thorac J] 2020 Mar 01; Vol. 21 (2), pp. 87-92. Date of Electronic Publication: 2020 Mar 01 (Print Publication: 2020). |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Aves Country of Publication: Turkey NLM ID: 101648545 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2149-2530 (Electronic) Linking ISSN: 21487197 NLM ISO Abbreviation: Turk Thorac J Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Original Publication: Şişli-Istanbul : Aves |
مستخلص: | Objectives: Vitamin D may play an important role in immunity and its deficiency has been related to increased respiratory infections. The aim of this study was to detect the prevalence of vitamin D deficiency and to investigate the relationship between radiological and clinical effects on adult bronchiectasis (BR) patients. Materials and Methods: A total of 130 patients with BR and 73 healthy individuals (control group) were enrolled in this study. Radiological severity was assessed using Modified Reiff Score. Results: The mean age of patients was 41.9±9.1 years (range, 18-85). The mean 25-hydroxyvitamin D (25(OH)D) level was 14.7±9.6 ng/mL in BR patients and 19.8±6.9 ng/mL in the control group (p=0.001). Moreover, 95 (73.1%) adult BR patients were categorized as vitamin D deficient. Patients in the vitamin D deficiency group had significantly higher Modified Medical Research Council scores than those in the group without vitamin D deficiency (p=0.036) The mean modified Reiff score was higher in the vitamin D deficient group than the without vitamin D deficiency group (6.9±3.8 vs 4.9± 2.7, p=0.001). Additionally, the vitamin D deficient group had lower forced vital capacity% predicted value (p=0.02). This model showed that Reiff score (OR, 1.285[1.039-1.590]; p=0.021) was independently related to vitamin D deficiency. Conclusion: We found that vitamin D deficiency is commonly seen in adult BR patients in a stable period. Moreover, it might be related to severe radiological findings on chest computed tomography and worse lung functions. |
References: | Clin Endocrinol (Oxf). 2008 Sep;69(3):374-81. (PMID: 18284636) Lancet Respir Med. 2016 Dec;4(12):969-979. (PMID: 27864036) Immunol Allergy Clin North Am. 2010 Aug;30(3):397-409. (PMID: 20670821) Arch Bronconeumol. 2017 Apr;53(4):186-191. (PMID: 28320552) Eur Respir J. 2017 Sep 9;50(3):. (PMID: 28889110) Cent Eur J Public Health. 2017 Sep;25(3):185-190. (PMID: 29022676) Am J Clin Nutr. 2000 Sep;72(3):690-3. (PMID: 10966885) N Engl J Med. 2007 Jul 19;357(3):266-81. (PMID: 17634462) Front Pediatr. 2017 Feb 15;5:19. (PMID: 28261574) J Res Pharm Pract. 2016 Jan-Mar;5(1):7-15. (PMID: 26985430) Paediatr Respir Rev. 2014 Jun;15(2):154-62. (PMID: 24332502) Dermatoendocrinol. 2012 Apr 1;4(2):191-7. (PMID: 22928076) Thorax. 2013 Jan;68(1):39-47. (PMID: 23076388) BMC Public Health. 2010 Dec 23;10:782. (PMID: 21176241) Nutr Res. 2011 Jan;31(1):48-54. (PMID: 21310306) Mayo Clin Proc. 2006 Mar;81(3):353-73. (PMID: 16529140) Caspian J Intern Med. 2012 Summer;3(3):451-5. (PMID: 24009913) Public Health Nutr. 2013 Jul;16(7):1306-13. (PMID: 22877974) Chest. 2005 Dec;128(6):3792-8. (PMID: 16354847) Chron Respir Dis. 2018 Nov;15(4):384-392. (PMID: 29490469) Curr Infect Dis Rep. 2013 Apr;15(2):148-57. (PMID: 23371406) J Asthma. 2014 Nov;51(9):950-5. (PMID: 24926743) J Immunol. 2004 Sep 1;173(5):2909-12. (PMID: 15322146) PLoS One. 2012;7(6):e38934. (PMID: 22737223) Thorax. 2003 Aug;58(8):680-5. (PMID: 12885984) J Pediatr. 2008 Aug;153(2):S4-S14. (PMID: 18639722) Am J Respir Crit Care Med. 2014 Mar 1;189(5):576-85. (PMID: 24328736) AJR Am J Roentgenol. 1995 Aug;165(2):261-7. (PMID: 7618537) Thorax. 2010 Mar;65(3):215-20. (PMID: 19996341) |
تواريخ الأحداث: | Date Created: 20200324 Latest Revision: 20200928 |
رمز التحديث: | 20231215 |
مُعرف محوري في PubMed: | PMC7089704 |
DOI: | 10.5152/TurkThoracJ.2019.18139 |
PMID: | 32202997 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2149-2530 |
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DOI: | 10.5152/TurkThoracJ.2019.18139 |