دورية أكاديمية

Vitamin D Deficiency and Radiological Findings in Adult Non-Cystic Fibrosis Bronchiectasis.

التفاصيل البيبلوغرافية
العنوان: Vitamin D Deficiency and Radiological Findings in Adult Non-Cystic Fibrosis Bronchiectasis.
المؤلفون: Niksarlıoğlu EY; Department of Chest Diseases, Health Science University, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Turkey., Kılıç L; Department of Chest Diseases, Health Science University, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Turkey., Bilici D; Department of Chest Diseases, Giresun Dr. Ali Menekşe Chest Diseases Hospital, Giresun, Turkey., Yiğitbaş B; Department of Chest Diseases, Health Science University, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Turkey., Uysal MA; Department of Chest Diseases, Health Science University, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Turkey., Çamsarı G; Department of Chest Diseases, Health Science University, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Turkey.
المصدر: Turkish thoracic journal [Turk Thorac J] 2020 Mar 01; Vol. 21 (2), pp. 87-92. Date of Electronic Publication: 2020 Mar 01 (Print Publication: 2020).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Aves Country of Publication: Turkey NLM ID: 101648545 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2149-2530 (Electronic) Linking ISSN: 21487197 NLM ISO Abbreviation: Turk Thorac J Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Şişli-Istanbul : Aves
مستخلص: Objectives: Vitamin D may play an important role in immunity and its deficiency has been related to increased respiratory infections. The aim of this study was to detect the prevalence of vitamin D deficiency and to investigate the relationship between radiological and clinical effects on adult bronchiectasis (BR) patients.
Materials and Methods: A total of 130 patients with BR and 73 healthy individuals (control group) were enrolled in this study. Radiological severity was assessed using Modified Reiff Score.
Results: The mean age of patients was 41.9±9.1 years (range, 18-85). The mean 25-hydroxyvitamin D (25(OH)D) level was 14.7±9.6 ng/mL in BR patients and 19.8±6.9 ng/mL in the control group (p=0.001). Moreover, 95 (73.1%) adult BR patients were categorized as vitamin D deficient. Patients in the vitamin D deficiency group had significantly higher Modified Medical Research Council scores than those in the group without vitamin D deficiency (p=0.036) The mean modified Reiff score was higher in the vitamin D deficient group than the without vitamin D deficiency group (6.9±3.8 vs 4.9± 2.7, p=0.001). Additionally, the vitamin D deficient group had lower forced vital capacity% predicted value (p=0.02). This model showed that Reiff score (OR, 1.285[1.039-1.590]; p=0.021) was independently related to vitamin D deficiency.
Conclusion: We found that vitamin D deficiency is commonly seen in adult BR patients in a stable period. Moreover, it might be related to severe radiological findings on chest computed tomography and worse lung functions.
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تواريخ الأحداث: Date Created: 20200324 Latest Revision: 20200928
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC7089704
DOI: 10.5152/TurkThoracJ.2019.18139
PMID: 32202997
قاعدة البيانات: MEDLINE
الوصف
تدمد:2149-2530
DOI:10.5152/TurkThoracJ.2019.18139