التفاصيل البيبلوغرافية
| العنوان: |
Efficacy of Maggot Debridement Therapy on Refractory Atypical Diabetic Foot Ulcers: An Open-Label Study. |
| المؤلفون: |
Siavash M; Isfahan University of Medical Sciences, Isfahan, Iran., Najjarnezhad A; Isfahan University of Medical Sciences, Isfahan, Iran., Mohseni N; Isfahan University of Medical Sciences, Isfahan, Iran., Abtahi SM; Isfahan University of Medical Sciences, Isfahan, Iran., Karimy A; Islamic Azad University of Isfahan, Isfahan, Iran., Sabzevari MH; Islamic Azad University of Shahreza, Isfahan, Iran. |
| المصدر: |
The international journal of lower extremity wounds [Int J Low Extrem Wounds] 2021 Dec; Vol. 20 (4), pp. 315-320. Date of Electronic Publication: 2020 May 05. |
| نوع المنشور: |
Journal Article |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: Sage Publications Country of Publication: United States NLM ID: 101128359 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-6941 (Electronic) Linking ISSN: 15347346 NLM ISO Abbreviation: Int J Low Extrem Wounds Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: Thousand Oaks, CA : Sage Publications, c2002- |
| مواضيع طبية MeSH: |
Diabetes Mellitus* , Diabetic Foot*/therapy , Diptera*, Animals ; Debridement ; Female ; Humans ; Larva ; Male ; Wound Healing |
| مستخلص: |
Atypical or refractory diabetic foot ulcers (DFUs) are still a major health problem. Maggot debridement therapy (MDT) by larva of Lucilia sericata is an ancient and a modern option for wound healing. It works by debridement, stimulation of wound healing, and disinfection. In this study, we aimed to evaluate the efficacy of MDT for healing atypical and refractory DFUs. Patients with atypical DFUs were selected and further evaluated for some predefined differential diagnoses like atypical fungal, parasitic, or bacterial infections, malignancy, trauma, and so on. Multiple MDT sessions were carried out. Ulcer size was measured before every MDT session. Complete wound healing, time to heal, and adverse effects were recorded as well. Forty-two DFU patients (26 men, 16 women) with 42 nonhealing atypical ulcers participated in this study. Complete wound healing was achieved in 35 patients (83.3%) by MDT. Complete debridement and then healing of the wounds happened in less than 1.79 ± 0.8 months. Four ulcers persisted, and 3 (7.1%) were eventually amputated. MDT may be considered as an effective treatment for atypical DFUs, which are unresponsive to conventional therapies. |
| فهرسة مساهمة: |
Keywords: Lucilia sericata; MD; Maggot; diabetic foot ulcer; larva |
| تواريخ الأحداث: |
Date Created: 20200507 Date Completed: 20211029 Latest Revision: 20211029 |
| رمز التحديث: |
20240829 |
| DOI: |
10.1177/1534734620920403 |
| PMID: |
32370633 |
| قاعدة البيانات: |
MEDLINE |
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