دورية أكاديمية
Prevalence and risk factors of hypogonadism in men with chronic renal failure.
| العنوان: | Prevalence and risk factors of hypogonadism in men with chronic renal failure. |
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| المؤلفون: | Oueslati I, Ounissi M, Talbi E, Azaiez S, Bacha MM, Ben Abdallah T |
| المصدر: | La Tunisie medicale [Tunis Med] 2020 Feb; Vol. 98 (2), pp. 138-143. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Societe Tunisienne Des Sciences Medicales Country of Publication: Tunisia NLM ID: 0413766 Publication Model: Print Cited Medium: Internet ISSN: 2724-7031 (Electronic) Linking ISSN: 00414131 NLM ISO Abbreviation: Tunis Med Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Tunis : Societe Tunisienne Des Sciences Medicales |
| مواضيع طبية MeSH: | Hypogonadism/*epidemiology , Hypogonadism/*etiology , Kidney Failure, Chronic/*complications , Kidney Failure, Chronic/*epidemiology, Adult ; Cross-Sectional Studies ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/epidemiology ; Diabetic Nephropathies/blood ; Diabetic Nephropathies/complications ; Diabetic Nephropathies/diagnosis ; Diabetic Nephropathies/epidemiology ; Gonadotropins/blood ; Humans ; Hypogonadism/blood ; Hypogonadism/diagnosis ; Kidney Failure, Chronic/blood ; Male ; Middle Aged ; Prevalence ; Prolactin/blood ; Risk Factors ; Testosterone/blood |
| مستخلص: | Aim: To determine the prevalence and the risk factors of hypogonadism in men with chronic renal failure (CRF). Methods: We conducted a cross sectional analysis in 48 men with CRF. Total testosterone, prolactin, and gonadotropins were measured in all patients. Hypogonadism was defined by a low level (<10 nmol/l) or a low normal level (10-14 nmol/l) of total testosterone. Results: The mean age was 53.31±10.22 years. Renal impairment was mild, moderate, severe and at end stage in 9,14,4 and 21 patients, respectively. Nineteen patients had been undergoing extra-renal purification. The average of total testosterone was 13.44±6.17 nmol/L. It was lower in patients with diabetic nephropathy (p=0.004). Hypogonadism was diagnosed in 22 patients (46 %). In this group, gonadotropins were normal in 21 cases and elevated in only one case. Hyperprolactinemia was retained in six patients. Type 2 diabetes (OR: 3.96; p=0.02) and diabetic nephropathy (OR=4.26; p=0.01) were the only risk factors of hypogonadism in our patients. Conclusion: Our results had demonstrated a high prevalence of hypogonadism in males with chronic renal failure. This hormone disorder was associated with type 2 diabetes and diabetic nephropathy. |
| المشرفين على المادة: | 0 (Gonadotropins) 3XMK78S47O (Testosterone) 9002-62-4 (Prolactin) |
| تواريخ الأحداث: | Date Created: 20200513 Date Completed: 20201001 Latest Revision: 20201001 |
| رمز التحديث: | 20221213 |
| PMID: | 32395803 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2724-7031 |
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