دورية أكاديمية

Fatal Methanol Poisoning Caused by Drinking Adulterated Locally Distilled Alcohol: Wakiso District, Uganda, June 2017.

التفاصيل البيبلوغرافية
العنوان: Fatal Methanol Poisoning Caused by Drinking Adulterated Locally Distilled Alcohol: Wakiso District, Uganda, June 2017.
المؤلفون: Doreen B; Uganda Public Health Fellowship Program, Kampala, Uganda., Eyu P; Uganda Public Health Fellowship Program, Kampala, Uganda., Okethwangu D; Uganda Public Health Fellowship Program, Kampala, Uganda., Biribawa C; Uganda Public Health Fellowship Program, Kampala, Uganda., Kizito S; Uganda Public Health Fellowship Program, Kampala, Uganda., Nakanwagi M; Uganda Public Health Fellowship Program, Kampala, Uganda., Nguna J; Uganda Public Health Fellowship Program, Kampala, Uganda., Nkonwa IH; Uganda Public Health Fellowship Program, Kampala, Uganda., Opio DN; Uganda Public Health Fellowship Program, Kampala, Uganda., Aceng FL; Uganda Public Health Fellowship Program, Kampala, Uganda., Alitubeera PH; Uganda Public Health Fellowship Program, Kampala, Uganda., Kadobera D; Uganda Public Health Fellowship Program, Kampala, Uganda., Kwesiga B; Uganda Public Health Fellowship Program, Kampala, Uganda., Bulage L; Uganda Public Health Fellowship Program, Kampala, Uganda., Ario AR; Uganda Public Health Fellowship Program, Kampala, Uganda., Zhu BP; US Centers for Diseases Control and Prevention, Kampala, Uganda.; Division of Global Health Protection, Center for Global Health, US Centers for Disease Control and Prevention, Atlanta, GA, USA.
المصدر: Journal of environmental and public health [J Environ Public Health] 2020 Apr 28; Vol. 2020, pp. 5816162. Date of Electronic Publication: 2020 Apr 28 (Print Publication: 2020).
نوع المنشور: Journal Article; Research Support, U.S. Gov't, P.H.S.
اللغة: English
بيانات الدورية: Publisher: Hindawi Pub. Corp Country of Publication: United States NLM ID: 101516361 Publication Model: eCollection Cited Medium: Internet ISSN: 1687-9813 (Electronic) Linking ISSN: 16879805 NLM ISO Abbreviation: J Environ Public Health Subsets: MEDLINE
أسماء مطبوعة: Original Publication: New York, NY : Hindawi Pub. Corp., [2009]-[2024]
مواضيع طبية MeSH: Foodborne Diseases/*mortality , Methanol/*poisoning, Adult ; Aged ; Case-Control Studies ; Female ; Foodborne Diseases/etiology ; Humans ; Male ; Middle Aged ; Uganda/epidemiology ; Young Adult
مستخلص: Background: Methanol, an industrial solvent, can cause illness and death if ingested. In June 2017, the Uganda Ministry of Health was notified of a cluster of deaths which occurred after drinking alcohol. We investigated to determine the cause of outbreak, identify risk factors, and recommend evidence-based control measures.
Methods: We defined a probable case as acute loss of eyesight and ≥1 of the following symptoms: profuse sweating, vomiting, dizziness, or loss of consciousness in a resident of either Nabweru or Nangabo Subcounty from 1 to 30 June 2017. In a case-control study, we compared exposures of case-patients and controls selected among asymptomatic neighbors who drank alcohol and matched by age and sex. We collected alcohol samples from implicated bars and wholesaler X for testing.
Results: We identified 15 cases; 12 (80%) died. Among case-patients, 12 (80%) were men; the median age was 43 (range: 23-66) years. Thirteen (87%) of 15 case-patients and 15 (25%) of 60 controls last drank a locally distilled alcohol at one of the three bars supplied by wholesaler X (OR M-H  = 15; 95% CI: 2.3-106). We found that alcohol sellers sometimes added methanol to drinking alcohol to increase their profit margin. Among the 10 alcohol samples from wholesaler X , the mean methanol content (1200 mg/L, range: 77-2711 mg/L) was 24 times higher than the safe level.
Conclusion: This outbreak was caused by drinking a locally distilled alcohol adulterated with methanol from wholesaler X . We recommended enforcing existing laws governing alcohol manufacture and sale. We recommended timely intravenous administration of ethanol to methanol poisoning victims.
Competing Interests: The authors declare that they have no conflicts of interest.
(Copyright © 2020 Birungi Doreen et al.)
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معلومات مُعتمدة: U2G GH000817 United States GH CGH CDC HHS; United States PEPFAR PEPFAR
المشرفين على المادة: Y4S76JWI15 (Methanol)
تواريخ الأحداث: Date Created: 20200515 Date Completed: 20201007 Latest Revision: 20201007
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC7204301
DOI: 10.1155/2020/5816162
PMID: 32405303
قاعدة البيانات: MEDLINE
الوصف
تدمد:1687-9813
DOI:10.1155/2020/5816162