دورية أكاديمية
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Gold nanoparticle-assisted enhancement in bioactive properties of Australian native plant extracts, Tasmannia lanceolata and Backhousia citriodora.

التفاصيل البيبلوغرافية
العنوان: Gold nanoparticle-assisted enhancement in bioactive properties of Australian native plant extracts, Tasmannia lanceolata and Backhousia citriodora.
المؤلفون: Khandanlou R; College of Environment, IT & Engineering, Charles Darwin University, Darwin 0909, Australia. Electronic address: roshanak.khandanlou@cdu.edu.au., Murthy V; College of Environment, IT & Engineering, Charles Darwin University, Darwin 0909, Australia., Wang H; College of Environment, IT & Engineering, Charles Darwin University, Darwin 0909, Australia.
المصدر: Materials science & engineering. C, Materials for biological applications [Mater Sci Eng C Mater Biol Appl] 2020 Jul; Vol. 112, pp. 110922. Date of Electronic Publication: 2020 Apr 04.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101484109 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-0191 (Electronic) Linking ISSN: 09284931 NLM ISO Abbreviation: Mater Sci Eng C Mater Biol Appl Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Amsterdam : Elsevier
مواضيع طبية MeSH: Gold/*chemistry , Metal Nanoparticles/*chemistry , Myrtaceae/*chemistry , Plant Extracts/*chemistry , Winteraceae/*chemistry, Australia ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Green Chemistry Technology ; Humans ; Metal Nanoparticles/toxicity ; Myrtaceae/metabolism ; Particle Size ; Plant Leaves/chemistry ; Plant Leaves/metabolism ; Winteraceae/metabolism
مستخلص: Green nanotechnology plays a significant role in developing effective treatment strategies for numerous diseases. The biological synthesis of metal nanoparticles (M-NPs) possesses suitable alternatives than chemical techniques. Using plant extract to synthesis M-NPs is an eco-friendly, non-toxic, and cost-effective that are suitable for biological applications and efforts are directed to explore the efficacy of these materials in cancer management. In this study, gold nanoparticles (Au-NPs) were synthesised by following a one-step green synthesis, a reaction between HAuCl 4 and biological molecules present in Tasmannia lanceolata leaf extract as a sole agent for both reduction and stabilisation. The characterisation techniques confirmed the successful synthesis of Au-NPs. TEM photograph revealed spherical shape nanoparticles with an average size of 7.10 ± 0.66 nm. The in-vitro cytotoxicity of Au-NPs was performed by analysing the percentage inhibition of cell viability using Resazurin assay on human liver cancer (HepG2), melanoma cancer (MM418 C1) and breast cancer (MCF-7) cell lines and compared with Au-NPs synthesised by using Backhousia citriodora leaf extract. The results showed that biosynthesised Au-NPs displayed greater inhibitory activity towards MCF-7 cancer cells proliferation compared to HepG2 and MM418 cancer cells. In addition, synthesised Au-NPs@ Tasmannia lanceolata leaf extract indicated higher inhibitory activity towards cancer cells compared to Au-NPs@ Backhousia citriodora leaf extract.
Competing Interests: Declaration of competing interest The authors declare that they have no conflict of interest.
(Copyright © 2020 Elsevier B.V. All rights reserved.)
فهرسة مساهمة: Keywords: Backhousia citriodora; Cancer cell lines; Gold nanoparticles; Resazurin assay; Tasmannia lanceolata
المشرفين على المادة: 0 (Plant Extracts)
7440-57-5 (Gold)
تواريخ الأحداث: Date Created: 20200516 Date Completed: 20210303 Latest Revision: 20210303
رمز التحديث: 20221213
DOI: 10.1016/j.msec.2020.110922
PMID: 32409072
قاعدة البيانات: MEDLINE
الوصف
تدمد:1873-0191
DOI:10.1016/j.msec.2020.110922