دورية أكاديمية

Epidemiological characteristics of obstructive sleep apnea in a hospital-based historical cohort in Lebanon.

التفاصيل البيبلوغرافية
العنوان: Epidemiological characteristics of obstructive sleep apnea in a hospital-based historical cohort in Lebanon.
المؤلفون: Coussa-Koniski ML; Respiratory Division, Lebanese American University Medical Center-Rizk Hospital (LAUMC-RH), Beirut, Lebanon., Saliba E; Lebanese American University, Gilbert and Rose-Marie Chagoury School of Medicine, Byblos, Lebanon., Welty FK; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America., Deeb M; Lebanese American University, Gilbert and Rose-Marie Chagoury School of Medicine, Byblos, Lebanon.
المصدر: PloS one [PLoS One] 2020 May 15; Vol. 15 (5), pp. e0231528. Date of Electronic Publication: 2020 May 15 (Print Publication: 2020).
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
أسماء مطبوعة: Original Publication: San Francisco, CA : Public Library of Science
مواضيع طبية MeSH: Severity of Illness Index*, Hypertension/*physiopathology , Obesity/*physiopathology , Sleep Apnea, Obstructive/*epidemiology , Snoring/*physiopathology, Adult ; Aged ; Female ; Humans ; Lebanon/epidemiology ; Male ; Medical History Taking ; Middle Aged ; Prevalence ; Retrospective Studies ; Risk Factors ; Sleep Apnea, Obstructive/diagnosis ; Young Adult
مستخلص: The objective of our study was to characterize and analyze the associations between OSA (obstructive sleep apnea) and other clinical variables in adult patients referred for sleep evaluation by polysomnography at a referral center in Beirut, Lebanon, in terms of sociodemographic features, symptoms presentation and comorbidities, and evaluate the burden of comorbidities associated with this disease. All individuals with suspected Sleep Apnea referred (January 2010-September 2017) for a one-night polysomnography were included. Demographics, self-reported symptoms and comorbidities were documented. The relationship between OSA severity and the presence of symptoms and comorbidities were evaluated using multivariate logistic regression. Overall, 663 subjects were assessed. Of these, 57.3% were referred from chest physicians, and sleep test results were abnormal in 589 subjects (88.8%) of whom 526 patients (89.3%) fulfilled diagnostic criteria for OSA; 76.3% were men and women were on average older. OSA was severe in 43.2% and more severe in men. Almost all patients were symptomatic with ~2-4 symptoms per patient and women presented with symptoms that are more atypical. Comorbidities were significantly higher in women. In the multivariate analysis, age, male sex, obesity, symptoms of snoring, excessive daytime somnolence and witnessed apneas were associated with OSA severity. Only age and obesity were associated with self-reported diagnosis of hypertension and diabetes. This is the first study in Lebanon to explore the characteristics of patients with polysomnography-diagnosed OSA. High prevalence of severe OSA and low referral rates in the medical community support promoting awareness for an earlier diagnosis and more personalized approach in this country.
Competing Interests: The research was funded by a grant from Philips. This does not alter our adherence to PLoS One policies on sharing data and materials.
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تواريخ الأحداث: Date Created: 20200516 Date Completed: 20200727 Latest Revision: 20200727
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC7228052
DOI: 10.1371/journal.pone.0231528
PMID: 32413035
قاعدة البيانات: MEDLINE
الوصف
تدمد:1932-6203
DOI:10.1371/journal.pone.0231528