دورية أكاديمية
أعرض في EDS

Spatial serosurvey of anti-Toxoplasma gondii antibodies in individuals with animal hoarding disorder and their dogs in Southern Brazil.

التفاصيل البيبلوغرافية
العنوان: Spatial serosurvey of anti-Toxoplasma gondii antibodies in individuals with animal hoarding disorder and their dogs in Southern Brazil.
المؤلفون: Cunha GRD; Department of Veterinary Medicine, Federal University of Paraná State, Curitiba, Paraná, Brazil., Pellizzaro M; Institute of Collective Health, Federal University of Bahia, Salvador, Bahia, Brazil., Martins CM; Department of Nursing and Public Health, Ponta Grossa State University, Ponta Grossa, Paraná, Brazil.; AAC&T Research Consulting, Curitiba, Paraná, Brazil., Rocha SM; Department of Veterinary Medicine, Federal University of Paraná State, Curitiba, Paraná, Brazil., Yamakawa AC; Department of Veterinary Hygiene and Public Health, School of Veterinary Medicine and Animals Science, São Paulo State University, Botucatu, São Paulo, Brazil., Silva ECD; Department of Veterinary Hygiene and Public Health, School of Veterinary Medicine and Animals Science, São Paulo State University, Botucatu, São Paulo, Brazil., Dos Santos AP; Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, Indiana, United States of America., Morikawa VM; Department of Collective Health, Federal University of Paraná State, Curitiba, Paraná, Brazil.; Secretary of Environment, Curitiba City Hall, Curitiba, Paraná, Brazil., Langoni H; Department of Veterinary Hygiene and Public Health, School of Veterinary Medicine and Animals Science, São Paulo State University, Botucatu, São Paulo, Brazil., Biondo AW; Department of Veterinary Medicine, Federal University of Paraná State, Curitiba, Paraná, Brazil.
المصدر: PloS one [PLoS One] 2020 May 15; Vol. 15 (5), pp. e0233305. Date of Electronic Publication: 2020 May 15 (Print Publication: 2020).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
أسماء مطبوعة: Original Publication: San Francisco, CA : Public Library of Science
مواضيع طبية MeSH: Antibodies, Protozoan/*blood , Dog Diseases/*epidemiology , Hoarding Disorder/*epidemiology , Toxoplasma/*immunology , Toxoplasmosis/*epidemiology, Animal Feed ; Animals ; Brazil/epidemiology ; Dog Diseases/blood ; Dog Diseases/immunology ; Dogs ; Geography, Medical ; Hoarding/blood ; Hoarding/epidemiology ; Hoarding/immunology ; Hoarding Disorder/blood ; Hoarding Disorder/immunology ; Humans ; Seroepidemiologic Studies ; Spatial Analysis ; Toxoplasmosis/blood ; Toxoplasmosis/immunology
مستخلص: Despite vulnerability and unsanitary conditions of animal hoarding may predispose environmental contamination and spread of vectors and pathogens, no study to date has focused on their impact on public health and zoonotic diseases. Accordingly, this study aimed to assess the seroprevalence of anti-Toxoplasma gondii antibodies and associated factors in individuals with animal hoarding disorder (AHD) and their dogs in Curitiba, Southern Brazil. Blood samples were obtained from 264 dogs (21 households) and 19 individuals with AHD (11 households). Their blood was tested by indirect fluorescent antibody test (IFAT). Overall, anti-Toxoplasma gondii seropositivity was found in 21/264 dogs (7.95%; 95% CI: 4.69-11.22) with titers ranging from 16 to 4096, and in 7/19 individuals with AHD (36.84%; CI: 15.15-58.53) with titers ranging from 16 to 64. Serological analysis for anti-T. gondii antibodies were considered positive in at least one individual or dog in 9/11 (81.82%; 95% CI: 59.03-100.00) cases that were thoroughly assessed. Surprisingly, the seropositivity of individuals with AHD and their dogs was among the lowest reportedly observed in human and dog populations of Brazil. There was no significant association between positive owners and positive dogs or the presence of cats in the household. Regard epidemiological variables, a significant association was found between dog's seropositivity and the type of dog food. To the authors' knowledge, the present study represents the first investigation of T. gondii seroprevalence in individuals with hoarding disorder and their dogs. In conclusion, despite low sanitary conditions, anti-Toxoplasma gondii antibodies frequency in individuals with AHD and their dogs are lower than the general population likely due to low protozoan load in such isolated households.
Competing Interests: The authors have declared that no competing interests exist.
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المشرفين على المادة: 0 (Antibodies, Protozoan)
تواريخ الأحداث: Date Created: 20200516 Date Completed: 20200811 Latest Revision: 20200811
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC7228105
DOI: 10.1371/journal.pone.0233305
PMID: 32413075
قاعدة البيانات: MEDLINE
الوصف
تدمد:1932-6203
DOI:10.1371/journal.pone.0233305