دورية أكاديمية

Endemic Chromoblastomycosis Caused Predominantly by Fonsecaea nubica, Madagascar 1 .

التفاصيل البيبلوغرافية
العنوان: Endemic Chromoblastomycosis Caused Predominantly by Fonsecaea nubica, Madagascar 1 .
المؤلفون: Rasamoelina T, Maubon D, Andrianarison M, Ranaivo I, Sendrasoa F, Rakotozandrindrainy N, Rakotomalala FA, Bailly S, Rakotonirina B, Andriantsimahavandy A, Rabenja FR, Andrianarivelo MR, Cornet M, Ramarozatovo LS
المصدر: Emerging infectious diseases [Emerg Infect Dis] 2020 Jun; Vol. 26 (6), pp. 1201-1211.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC) Country of Publication: United States NLM ID: 9508155 Publication Model: Print Cited Medium: Internet ISSN: 1080-6059 (Electronic) Linking ISSN: 10806040 NLM ISO Abbreviation: Emerg Infect Dis Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Atlanta, GA : National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC), [1995-
مواضيع طبية MeSH: Ascomycota*/genetics , Chromoblastomycosis*/diagnosis , Chromoblastomycosis*/drug therapy , Chromoblastomycosis*/epidemiology, Antifungal Agents/therapeutic use ; Fonsecaea ; Humans ; Madagascar/epidemiology
مستخلص: Chromoblastomycosis is an implantation fungal infection. Twenty years ago, Madagascar was recognized as the leading focus of this disease. We recruited patients in Madagascar who had chronic subcutaneous lesions suggestive of dermatomycosis during March 2013-June 2017. Chromoblastomycosis was diagnosed in 50 (33.8%) of 148 patients. The highest prevalence was in northeastern (1.47 cases/100,000 persons) and southern (0.8 cases/100,000 persons) Madagascar. Patients with chromoblastomycosis were older (47.9 years) than those without (37.5 years) (p = 0.0005). Chromoblastomycosis was 3 times more likely to consist of leg lesions (p = 0.003). Molecular analysis identified Fonsecaea nubica in 23 cases and Cladophialophora carrionii in 7 cases. Of 27 patients who underwent follow-up testing, none were completely cured. We highlight the persistence of a high level of chromoblastomycosis endemicity, which was even greater at some locations than 20 years ago. We used molecular tools to identify the Fonsecaea sp. strains isolated from patients as F. nubica.
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فهرسة مساهمة: Keywords: Fonseca pedrosoi; Fonsecaea nubica; Madagascar; chromoblastomycosis; clinical outcome; clinical presentation; dermatomycosis; epidemiology; fungal infections; fungi; molecular diagnosis; prevalence
المشرفين على المادة: 0 (Antifungal Agents)
SCR Organism: Cladophialophora carrionii
تواريخ الأحداث: Date Created: 20200523 Date Completed: 20210618 Latest Revision: 20240404
رمز التحديث: 20240404
مُعرف محوري في PubMed: PMC7258462
DOI: 10.3201/eid2606.191498
PMID: 32441639
قاعدة البيانات: MEDLINE
الوصف
تدمد:1080-6059
DOI:10.3201/eid2606.191498