دورية أكاديمية

Transoral laser microsurgery for Tis, T1, and T2 glottic carcinoma: 5-year follow-up.

التفاصيل البيبلوغرافية
العنوان: Transoral laser microsurgery for Tis, T1, and T2 glottic carcinoma: 5-year follow-up.
المؤلفون: De Seta D; Department of Surgery, Unit of Otolaryngology, University of Cagliari, Cagliari, Italy., Campo F; Department of Sense Organs, Sapienza University of Rome, Viale dell'Università, 33, 00186, Rome, Italy. flaminiacampo@gmail.com., D'Aguanno V; Department of Sense Organs, Sapienza University of Rome, Viale dell'Università, 33, 00186, Rome, Italy., Ralli M; Department of Sense Organs, Sapienza University of Rome, Viale dell'Università, 33, 00186, Rome, Italy., Greco A; Department of Sense Organs, Sapienza University of Rome, Viale dell'Università, 33, 00186, Rome, Italy., Russo FY; Department of Sense Organs, Sapienza University of Rome, Viale dell'Università, 33, 00186, Rome, Italy., de Vincentiis M; Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, 00186, Rome, Italy.
المصدر: Lasers in medical science [Lasers Med Sci] 2021 Apr; Vol. 36 (3), pp. 507-512. Date of Electronic Publication: 2020 May 29.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer Country of Publication: England NLM ID: 8611515 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-604X (Electronic) Linking ISSN: 02688921 NLM ISO Abbreviation: Lasers Med Sci Subsets: MEDLINE
أسماء مطبوعة: Publication: London : Springer
Original Publication: London : Baillière Tindall, c1986-
مواضيع طبية MeSH: Laser Therapy* , Microsurgery*, Glottis/*pathology , Glottis/*surgery , Laryngeal Neoplasms/*surgery, Adult ; Aged ; Aged, 80 and over ; Cohort Studies ; Female ; Follow-Up Studies ; Humans ; Kaplan-Meier Estimate ; Laryngeal Neoplasms/pathology ; Male ; Margins of Excision ; Middle Aged ; Neoplasm Staging ; Postoperative Complications/etiology ; Retrospective Studies ; Treatment Outcome
مستخلص: The aim of this retrospective study is to evaluate the results obtained with CO 2 TOLMS in patients with Tis, T1, and T2 glottic tumors at our Department from 2004 to 2016 treated with CO 2 TOLMS. One hundred eighty-five patients having a median age of 67 years (range 42-88) were included in the present analysis. The tumor stages of the patients included 134 pTis-T1a, 12 pT1b, and 39 pT2 cases. Median duration of follow-up for the whole study cohort was 55 months (range 24-108 months). At 5-year follow-up, local control was 91%, 83%, and 79.4% for T1a, T1b, and T2 respectively. Disease-specific survival was 95.5%, 91.6%, and 92.3%. Overall survival was 73.8%, 91.6%, and 82%, and larynx preservation was 96.2%, 83%, and 84.6%. This study confirms that CO 2 TOLMS is a safe and standard therapy for selected T1 and T2 glottic carcinoma, and our review on T2 glottic cancer suggests that CO 2 TOLMS represents a reliable option in terms of overall survival, disease-specific survival, and laryngeal preservation. However, patients with anterior commissure involvement and T2 cancer should be evaluated with a preoperative MRI in order to exclude the infiltration of the laryngeal framework and to quantify the neoplastic involvement of para-glottic space.
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فهرسة مساهمة: Keywords: Anterior commissure; Larynx; Laser; Outcomes; T1 glottic cancer; T2 glottic cancer; TOLMS
تواريخ الأحداث: Date Created: 20200531 Date Completed: 20210326 Latest Revision: 20210326
رمز التحديث: 20231215
DOI: 10.1007/s10103-020-03049-4
PMID: 32472425
قاعدة البيانات: MEDLINE
الوصف
تدمد:1435-604X
DOI:10.1007/s10103-020-03049-4