دورية أكاديمية
Time in Therapeutic Range for Dialysis Patients on Warfarin: Determination and the Effect of Dietary Intervention.
| العنوان: | Time in Therapeutic Range for Dialysis Patients on Warfarin: Determination and the Effect of Dietary Intervention. |
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| المؤلفون: | Niznik RS; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN., Hoel RW; Department of Pharmacy, Mayo Clinic, Rochester, MN., Vaughan LE; Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN., Majorowicz RR; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN., Albright RC Jr; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN. Electronic address: albright.robert@mayo.edu. |
| المصدر: | Mayo Clinic proceedings [Mayo Clin Proc] 2020 Jun; Vol. 95 (6), pp. 1206-1211. |
| نوع المنشور: | Journal Article; Multicenter Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: [Oxford, England] Country of Publication: England NLM ID: 0405543 Publication Model: Print Cited Medium: Internet ISSN: 1942-5546 (Electronic) Linking ISSN: 00256196 NLM ISO Abbreviation: Mayo Clin Proc Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Jan. 2012- : [Oxford, England] : Elsevier Original Publication: Rochester, MN : Mayo Foundation for Medical Education and Research |
| مواضيع طبية MeSH: | Anticoagulants/*therapeutic use , Renal Dialysis/*methods , Warfarin/*therapeutic use, Aged ; Atrial Fibrillation/drug therapy ; Diet ; Diet Therapy/methods ; Female ; Humans ; International Normalized Ratio ; Male ; Middle Aged ; Retrospective Studies ; Time Factors ; Vitamin K/administration & dosage |
| مستخلص: | This study aimed to identify the time in therapeutic range (TTR) for dialysis patients on warfarin, and improve TTR with dietary review and intervention of interacting foods. We identified 151 patients undergoing hemodialysis in two units who were being treated with warfarin from January 1, 2010, through February 1, 2018, who were included in the overall TTR study. Of these, 15 patients were available to undergo the dietary intervention. International normalized ratio values were collected retrospectively for all eligible hemodialysis patients, and TTR was calculated for each period in which the patient was on hemodialysis. Patients who were available and agreed to the intervention underwent targeted dietician review of interacting foods, and their TTR post-treatment was calculated. The median (interquartile range [IQR]) TTR was 44 (IQR, 29 to 53) % among the 151 patients. Among the 15 patients who underwent the intervention, median (IQR) TTR was 52 (IQR, 32 to 56) pre-intervention and 51 (IQR, 38 to 69) post-intervention (P=0.53). TTR for dialysis patients is low in this overall cohort despite patients being seen at an integrated health care system. Focused improvement projects such as dietary review of interacting foods may help increase a patient's TTR. (Copyright © 2020 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.) |
| التعليقات: | Comment in: Mayo Clin Proc. 2020 Jun;95(6):1099-1101. (PMID: 32498768) |
| المشرفين على المادة: | 0 (Anticoagulants) 12001-79-5 (Vitamin K) 5Q7ZVV76EI (Warfarin) |
| تواريخ الأحداث: | Date Created: 20200606 Date Completed: 20201001 Latest Revision: 20201001 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.mayocp.2020.02.030 |
| PMID: | 32498776 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1942-5546 |
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| DOI: | 10.1016/j.mayocp.2020.02.030 |