دورية أكاديمية
أعرض في EDS

Reliability of heterophyid antigens in heterologous protection against human schistosomiasis.

التفاصيل البيبلوغرافية
العنوان: Reliability of heterophyid antigens in heterologous protection against human schistosomiasis.
المؤلفون: Hegazy AHA; Asyut, Egypt., Galal LA; Asyut, Egypt., Hassan TM; Asyut, Egypt., Khalifa RMA; Asyut, Egypt.
المصدر: Journal of parasitic diseases : official organ of the Indian Society for Parasitology [J Parasit Dis] 2020 Jun; Vol. 44 (2), pp. 349-354. Date of Electronic Publication: 2020 Jan 24.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer India Country of Publication: India NLM ID: 9713059 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0971-7196 (Print) Linking ISSN: 09717196 NLM ISO Abbreviation: J Parasit Dis Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: <2009-> : New Dehli : Springer India
Original Publication: Lucknow, India : Indian Society for Parasitology, c1995-
مستخلص: Schistosomiasis is a neglected tropical parasitic disease which has been controlled by praziquantel for many decades; however, reemergence of praziquantel resistant strains has been a continuous threat. Therefore, the development of reliable antischistosomal vaccine is significantly demanded for optimal control. In the present study, comparison among Schistosoma haematobium, Schsitosoma mansoni and Pygidiopsis genata crude antigens was carried out by Sodium dodecyl sulphate polyacrylamide gel electrophoresis. Hyperimmunization of rabbits with tested parasites' crude antigens was done to obtain hyperimmune sera. Western blotting was applied to show cross reactivity between parasites' crude antigens and either homologous or heterologous sera. Although there was no cross reaction between P . genata crude antigens and sera of both Schistosoma species and vice versa; it is supposed that the immunogenic band at 79 kDa might develop cross reactivity with Schistosma spp. SEA fractionation if used in future studies.
Competing Interests: Conflict of interestThe authors declare that they have no conflict of interest.
(© Indian Society for Parasitology 2020.)
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فهرسة مساهمة: Keywords: Heterologous immunity; Pygidiopsis genata; SDS-PAGE; Schistosomiasis; Western blotting
تواريخ الأحداث: Date Created: 20200609 Latest Revision: 20240328
رمز التحديث: 20240329
مُعرف محوري في PubMed: PMC7244675
DOI: 10.1007/s12639-020-01195-8
PMID: 32508409
قاعدة البيانات: MEDLINE
الوصف
تدمد:0971-7196
DOI:10.1007/s12639-020-01195-8