دورية أكاديمية
Evaluation of the Microbial Load and Heavy Metal Content of Two Polyherbal Antimalarial Products on the Ghanaian Market.
| العنوان: | Evaluation of the Microbial Load and Heavy Metal Content of Two Polyherbal Antimalarial Products on the Ghanaian Market. |
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| المؤلفون: | Turkson BK; Institute of Traditional and Alternative Medicine, University of Health and Allied Sciences, Ho, Ghana., Mensah MLK; Department of Herbal Medicine, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Sam GH; Department of Herbal Medicine, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Mensah AY; Department of Pharmacognosy, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Amponsah IK; Department of Pharmacognosy, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Ekuadzi E; Department of Pharmacognosy, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Komlaga G; Department of Pharmacognosy, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana., Achaab E; Tafo Government Hospital, Ghana Health Service, Accra, Ghana. |
| المصدر: | Evidence-based complementary and alternative medicine : eCAM [Evid Based Complement Alternat Med] 2020 May 15; Vol. 2020, pp. 1014273. Date of Electronic Publication: 2020 May 15 (Print Publication: 2020). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Hindawi Pub Country of Publication: United States NLM ID: 101215021 Publication Model: eCollection Cited Medium: Print ISSN: 1741-427X (Print) Linking ISSN: 1741427X NLM ISO Abbreviation: Evid Based Complement Alternat Med Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Publication: 2011- : New York, NY : Hindawi Pub. Original Publication: Oxford, UK : Oxford University Press, c2004- |
| مستخلص: | The use of herbal products has increased and become more popularized globally; however, limited studies coupled with questions related to the quality and safety of these herbal products have been raised. Herbal products with hope of their nontoxicity may play a role of alternative to overcome the problems of multi-drug resistant pathogens. Medicinal plants used as raw materials for production may have quality and safety issues due to proximity to wastewater application of fungicides and pesticides, which may be directly deposited superficially or absorbed by the plant system. Therefore, possible contamination of some Ghanaian herbal products cannot be ignored, as it may severely affect human life in the process of treatment. Aim . To evaluate the microbial load and the presence of toxic heavy metals in Mist Amen Fevermix and Edhec Malacure , two polyherbal products used in the treatment of uncomplicated malaria in Ghana. Methods . Thermo Elemental M5 Atomic Absorption Spectrophotometer (AAS) fitted with graphite furnace and an auto sampler was used to determine the heavy metal contents of the herbal products. The herbal samples were evaluated for the microbial load by using the appropriate culture media. Results and Analysis . Mist Amen Fevermix and Edhec Malacure complied with the safety limits evaluated for all different microbial counts and contamination. The following heavy metals were present in Mist Amen Fevermix and Edhec Malacure Mixture : Fe, Ni, K, Zn, Hg, Cu, Mn, Cr, Cd, Pb, Fe, Cu, K, and Na. Ni was below detectable limit in Edhec Malacure . Conclusion . Mist Amen Fevermix and Edhec Malacure may be assured of safety. The products contained heavy metals, but all were within acceptable limit established by the FAO/WHO. The levels of microbial contamination were below the maximum acceptable limit. Competing Interests: The authors declare that they have no conflicts of interest. (Copyright © 2020 Bernard K. Turkson et al.) |
| References: | Pan Afr Med J. 2016 Mar 01;23:65. (PMID: 27217889) Fungal Genet Biol. 2014 May;66:1-10. (PMID: 24594211) World J Gastroenterol. 2013 Apr 28;19(16):2529-36. (PMID: 23674855) Cancer Epidemiol Biomarkers Prev. 2009 Mar;18(3):846-53. (PMID: 19273485) Evid Based Complement Alternat Med. 2015;2015:243593. (PMID: 26587044) Ghana Med J. 2010 Mar;44(1):3-9. (PMID: 21326984) J Agric Food Chem. 2000 Jun;48(6):2300-4. (PMID: 10888541) Afr J Tradit Complement Altern Med. 2007 Oct 27;5(1):74-8. (PMID: 20162058) |
| تواريخ الأحداث: | Date Created: 20200609 Latest Revision: 20200928 |
| رمز التحديث: | 20240829 |
| مُعرف محوري في PubMed: | PMC7246409 |
| DOI: | 10.1155/2020/1014273 |
| PMID: | 32508940 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1741-427X |
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| DOI: | 10.1155/2020/1014273 |