دورية أكاديمية
In vitro comparison of personalized 3D printed versus standard expandable titanium vertebral body replacement implants in the mid-thoracic spine using entire rib cage specimens.
| العنوان: | In vitro comparison of personalized 3D printed versus standard expandable titanium vertebral body replacement implants in the mid-thoracic spine using entire rib cage specimens. |
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| المؤلفون: | Liebsch C; Institute of Orthopaedic Research and Biomechanics, Trauma Research Centre Ulm, Ulm University, Ulm, Germany., Aleinikov V; National Center for Neurosurgery, Nur-Sultan, Kazakhstan., Kerimbayev T; National Center for Neurosurgery, Nur-Sultan, Kazakhstan., Akshulakov S; National Center for Neurosurgery, Nur-Sultan, Kazakhstan., Kocak T; Department of Orthopedics, Ulm University, Ulm, Germany., Vogt M; Institute of Orthopaedic Research and Biomechanics, Trauma Research Centre Ulm, Ulm University, Ulm, Germany., Jansen JU; Institute of Orthopaedic Research and Biomechanics, Trauma Research Centre Ulm, Ulm University, Ulm, Germany., Wilke HJ; Institute of Orthopaedic Research and Biomechanics, Trauma Research Centre Ulm, Ulm University, Ulm, Germany. Electronic address: hans-joachim.wilke@uni-ulm.de. |
| المصدر: | Clinical biomechanics (Bristol, Avon) [Clin Biomech (Bristol, Avon)] 2020 Aug; Vol. 78, pp. 105070. Date of Electronic Publication: 2020 Jun 03. |
| نوع المنشور: | Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Science Country of Publication: England NLM ID: 8611877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1271 (Electronic) Linking ISSN: 02680033 NLM ISO Abbreviation: Clin Biomech (Bristol, Avon) Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 1995- : Oxford : Elsevier Science Original Publication: Bristol, UK : J. Wright, c1986- |
| مواضيع طبية MeSH: | Mechanical Phenomena* , Printing, Three-Dimensional* , Titanium*, Rib Cage/*surgery , Spinal Fusion/*instrumentation , Thoracic Vertebrae/*surgery , Vertebral Body/*surgery, Biomechanical Phenomena ; Cadaver ; Humans ; Male ; Reference Standards ; Rotation ; Spinal Fusion/standards |
| مستخلص: | Background: Expandable titanium implants have proven their suitability as vertebral body replacement device in several clinical and biomechanical studies. Potential stabilizing features of personalized 3D printed titanium devices, however, have never been explored. This in vitro study aimed to prove their equivalence regarding primary stability and three-dimensional motion behavior in the mid-thoracic spine including the entire rib cage. Methods: Six fresh frozen human thoracic spine specimens with intact rib cages were loaded with pure moments of 5 Nm while performing optical motion tracking of all vertebrae. Following testing in intact condition (1), the specimens were tested after inserting personalized 3D printed titanium vertebral body replacement implants (2) and the two standard expandable titanium implants Obelisc™ (3) and Synex™ (4), each at T6 level combined with posterior pedicle screw-rod fixation from T4 to T8. Findings: No significant differences (P < .05) in primary and secondary T1-T12 ranges of motion were found between the three implant types. Compared to the intact condition, slight decreases of the range of motion were found, which were significant for Synex™ in primary flexion/extension (-17%), specifically at T3-T4 level (-46%), primary lateral bending (-18%), and secondary lateral bending during primary axial rotation (-53%). Range of motion solely increased at T8-T9 level, while being significant only for Obelisc™ (+35%). Interpretation: Personalized 3D printed vertebral body replacement implants provide a promising alternative to standard expandable devices regarding primary stability and three-dimensional motion behavior in the mid-thoracic spine due to the stabilizing effect of the rib cage. Competing Interests: Declaration of Competing Interest The authors declare that they have no conflicts of interest to disclose. (Copyright © 2020. Published by Elsevier Ltd.) |
| فهرسة مساهمة: | Keywords: Biomechanics; In vitro study; Primary stability; Rib cage; Thoracic spine; Vertebral body replacement implant |
| المشرفين على المادة: | D1JT611TNE (Titanium) |
| تواريخ الأحداث: | Date Created: 20200613 Date Completed: 20210422 Latest Revision: 20210422 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.clinbiomech.2020.105070 |
| PMID: | 32531440 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1879-1271 |
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| DOI: | 10.1016/j.clinbiomech.2020.105070 |