تقرير
Neuroendocrine carcinoma of the ampulla of Vater: a case report, review and recommendations.
| العنوان: | Neuroendocrine carcinoma of the ampulla of Vater: a case report, review and recommendations. |
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| المؤلفون: | Kleinschmidt TK; Department of Medical Education, Brookwood Baptist Health Systems, Birmingham, AL, USA.; Department of Hepatobiliary and Pancreatic Surgery, Grandview Medical Center, Birmingham, AL, USA., Christein J; Department of Hepatobiliary and Pancreatic Surgery, Grandview Medical Center, Birmingham, AL, USA. |
| المصدر: | Journal of surgical case reports [J Surg Case Rep] 2020 Jun 05; Vol. 2020 (6), pp. rjaa119. Date of Electronic Publication: 2020 Jun 05 (Print Publication: 2020). |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 101560169 Publication Model: eCollection Cited Medium: Print ISSN: 2042-8812 (Print) Linking ISSN: 20428812 NLM ISO Abbreviation: J Surg Case Rep Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Publication: 2013- : Oxford : Oxford University Press Original Publication: 2010-2012: Halesowen, UK : JSCR Publishing Limited |
| مستخلص: | Neuroendocrine tumor (NET) of the ampulla of Vater is a rare presentation of biliary obstruction. Here, we present a case of NET and discuss the current recommendations that necessitate different management and surgical treatment than other sites. A 56-year-old Caucasian female presented with 2 years of right upper quadrant pain. Workup revealed a well-differentiated 2.2 cm NET at the ampulla with 0 MF/10 HPF, Stage 1A T2NOMO. Whipple procedure performed with 2.2 cm ampullary NET with 1 of the 15 lymph node metastases and <2 mitoses in 10 HPF. TNM classification: Stage IV T2N1MO. Regardless of tumor size, NETs metastasize in half of cases. Local excisions including endoscopic and laparoscopic ampullectomy were recommended only for poor surgical candidates. Ampullary NETs behave more aggressively than nonampullary NETs and their biological behaviors are irrespective of size. For patients of acceptable surgical risk, we recommend radical resection utilizing Whipple procedure. (Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2020.) |
| References: | J Gastrointest Surg. 2014 Feb;18(2):354-62. (PMID: 24114680) J Clin Oncol. 2008 Jun 20;26(18):3063-72. (PMID: 18565894) Clin Gastroenterol Hepatol. 2010 Jan;8(1):e5-6. (PMID: 19643204) Arch Pathol Lab Med. 2010 Nov;134(11):1692-6. (PMID: 21043824) JOP. 2012 May 10;13(3):263-7. (PMID: 22572129) Indian J Cancer. 2007 Apr-Jun;44(2):90-2. (PMID: 17938486) World J Gastroenterol. 2010 Mar 28;16(12):1527-32. (PMID: 20333796) Arq Gastroenterol. 2013 Jan-Mar;50(1):3-9. (PMID: 23657299) Int J Clin Exp Pathol. 2012;5(1):52-7. (PMID: 22295147) Hepatobiliary Pancreat Dis Int. 2008 Aug;7(4):422-5. (PMID: 18693180) |
| تواريخ الأحداث: | Date Created: 20200616 Latest Revision: 20200928 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC7276669 |
| DOI: | 10.1093/jscr/rjaa119 |
| PMID: | 32537123 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2042-8812 |
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| DOI: | 10.1093/jscr/rjaa119 |