دورية أكاديمية
Caspase-8 and FADD: Where Cell Death and Inflammation Collide.
| العنوان: | Caspase-8 and FADD: Where Cell Death and Inflammation Collide. |
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| المؤلفون: | Amaral MP; Center for Cellular and Molecular Therapy (CTCMol), Federal University of São Paulo (UNIFESP), São Paulo, Brazil., Bortoluci KR; Center for Cellular and Molecular Therapy (CTCMol), Federal University of São Paulo (UNIFESP), São Paulo, Brazil. Electronic address: kbortoluci@gmail.com. |
| المصدر: | Immunity [Immunity] 2020 Jun 16; Vol. 52 (6), pp. 890-892. |
| نوع المنشور: | Journal Article; Comment |
| اللغة: | English |
| بيانات الدورية: | Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Cambridge, MA : Cell Press Original Publication: Cambridge, Mass. : Cell Press, c1994- |
| مواضيع طبية MeSH: | Gastrointestinal Microbiome*, Animals ; Apoptosis ; Caspase 8/genetics ; Caspase 8/metabolism ; Cell Death ; Epithelial Cells/metabolism ; Fas-Associated Death Domain Protein/genetics ; Fas-Associated Death Domain Protein/metabolism ; Homeostasis ; Inflammation ; Intracellular Signaling Peptides and Proteins ; Mice ; Phosphate-Binding Proteins ; Protein Kinases |
| مستخلص: | Caspase-8 is a master regulator of cell death pathways, although its regulation during inflammation remains elusive. Using elegant mouse genetic approaches, Schwarzer et al. and Tummers et al. revealed the importance of FADD in regulating caspase-8-mediated inflammatory responses and gut homeostasis. (Copyright © 2020 Elsevier Inc. All rights reserved.) |
| التعليقات: | Comment on: Immunity. 2020 Jun 16;52(6):978-993.e6. (PMID: 32362323) Comment on: Immunity. 2020 Jun 16;52(6):994-1006.e8. (PMID: 32428502) |
| المشرفين على المادة: | 0 (Fadd protein, mouse) 0 (Fas-Associated Death Domain Protein) 0 (Gsdmd protein, mouse) 0 (Intracellular Signaling Peptides and Proteins) 0 (Phosphate-Binding Proteins) EC 2.7.- (MLKL protein, mouse) EC 2.7.- (Protein Kinases) EC 3.4.22.- (Caspase 8) |
| تواريخ الأحداث: | Date Created: 20200620 Date Completed: 20210312 Latest Revision: 20210608 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/j.immuni.2020.05.008 |
| PMID: | 32553174 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1097-4180 |
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| DOI: | 10.1016/j.immuni.2020.05.008 |