دورية أكاديمية
Equine Aging and the Oocyte: A Potential Model for Reproductive Aging in Women.
| العنوان: | Equine Aging and the Oocyte: A Potential Model for Reproductive Aging in Women. |
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| المؤلفون: | Carnevale EM; Equine Reproduction Laboratory, Department of Biomedical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO. Electronic address: Elaine.Carnevale@colostate.edu., Catandi GD; Equine Reproduction Laboratory, Department of Biomedical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO., Fresa K; Equine Reproduction Laboratory, Department of Biomedical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO. |
| المصدر: | Journal of equine veterinary science [J Equine Vet Sci] 2020 Jun; Vol. 89, pp. 103022. Date of Electronic Publication: 2020 Apr 15. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 8216840 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0737-0806 (Print) Linking ISSN: 07370806 NLM ISO Abbreviation: J Equine Vet Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2003- : New York : Elsevier Original Publication: [Wildomar, CA : William E. Jones, c1981- |
| مواضيع طبية MeSH: | Oocytes* , Reproduction*, Aging ; Animals ; Female ; Fertility ; Horses ; Meiosis |
| مستخلص: | Numerous similarities in reproductive aging have been documented between the mare and woman. Aging is associated with a decline in fertility. In mares and women, oocyte transfer procedures were initially used to establish that oocyte donor age is associated with oocyte quality. Age-associated differences in oocytes include altered morphology, gene expression, and developmental potential. Reactive oxygen species and mitochondrial dysfunction are thought to be important contributors to loss of oocyte quality. In the woman, aneuploidy is a primary consideration with maternal aging. Although misalignment of chromosomes during meiosis has been observed in the mare, less is known in this area. Reproductive aging will be reviewed in the mare and compared with the woman with emphasis on factors that affect oocyte quality and developmental potential. Areas in which the mare could be used as a research model to study reproductive aging in women will be highlighted. (Copyright © 2020. Published by Elsevier Inc.) |
| فهرسة مساهمة: | Keywords: Age; Embryo; Fertility; Mare; Oocyte; Woman |
| تواريخ الأحداث: | Date Created: 20200622 Date Completed: 20210122 Latest Revision: 20210122 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.jevs.2020.103022 |
| PMID: | 32563447 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0737-0806 |
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| DOI: | 10.1016/j.jevs.2020.103022 |