دورية أكاديمية
أعرض في EDS

Long-term mortality in very old patients with cancer admitted to intensive care unit: A retrospective cohort study.

التفاصيل البيبلوغرافية
العنوان: Long-term mortality in very old patients with cancer admitted to intensive care unit: A retrospective cohort study.
المؤلفون: Nassar Junior AP; Intensive Care Unit, A.C. Camargo Cancer Center, São Paulo, Brazil. Electronic address: paulo.nassar@accamargo.org.br., Trevisani MDS; Research Nurse, The State of São Paulo Cancer Institute, Brazil., Bettim BB; International Research Center, A.C. Camargo Cancer Center, São Paulo, Brazil., Caruso P; Intensive Care Unit, A.C. Camargo Cancer Center, São Paulo, Brazil; Discipline of Pulmonology, Heart Institute (InCor), University of São Paulo, Brazil.
المصدر: Journal of geriatric oncology [J Geriatr Oncol] 2021 Jan; Vol. 12 (1), pp. 106-111. Date of Electronic Publication: 2020 Jun 19.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101534770 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-4076 (Electronic) Linking ISSN: 18794068 NLM ISO Abbreviation: J Geriatr Oncol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Amsterdam : Elsevier
مواضيع طبية MeSH: Intensive Care Units* , Neoplasms*/therapy, Hospital Mortality ; Hospitalization ; Humans ; Patient Discharge ; Retrospective Studies
مستخلص: Background: Long-term outcomes of older patients referred to intensive care unit (ICU) are of paramount importance for care planning and counseling of patients and relatives.
Methods: We performed a retrospective study with patients aged ≥80 years admitted to ICU from 2011 to 2017 in a cancer center. We performed two Cox proportional hazard regressions. In the first, we tested whether type of cancer (solid locoregional, solid metastatic or hematologic), Eastern Cooperative Oncology Group Performance Status (ECOG PS), and comorbidities [Charlson Comorbidity Index - CCI]) were associated with one-year mortality in all patients. In the second, we assessed whether delirium, use of vasopressors, mechanical ventilation, renal replacement therapy, and forgoing life-sustaining therapies were associated with one-year mortality in survivors to hospital discharge.
Results: Of 763 patients included, 482 (62.3%) patients died at one year. Metastatic cancer was significantly associated with one-year mortality (HR = 1.97; CI 95%, 1.16-3.36), but hematologic cancer, CCI and ECOG PS were not. Among patients who survived to hospital discharge, delirium, use of vasopressors, mechanical ventilation, renal replacement therapy and decisions to forgo life-sustaining therapies in ICU were not associated with one-year mortality.
Conclusions: Metastatic disease at ICU admission was associated with one-year mortality in patients aged ≥80 years. Delirium, use of vasopressors, mechanical ventilation and renal replacement therapy and decisions to forgo life-sustaining therapies in ICU were not associated with one-year mortality among the patients discharged from hospital.
Competing Interests: Declaration of Competing Interest The authors do not have any conflict of interest to declare
(Copyright © 2020 Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: Aged 80 and over; Cancer; Critical care; Decision making; Mortality
تواريخ الأحداث: Date Created: 20200623 Date Completed: 20210728 Latest Revision: 20210728
رمز التحديث: 20231215
DOI: 10.1016/j.jgo.2020.06.005
PMID: 32565146
قاعدة البيانات: MEDLINE
الوصف
تدمد:1879-4076
DOI:10.1016/j.jgo.2020.06.005