دورية أكاديمية
أعرض في EDS

Investigation of the survival viability of cervical cancer cells (HeLa) under visible light induced photo-catalysis with facile synthesized WO 3 /ZnO nanocomposite.

التفاصيل البيبلوغرافية
العنوان: Investigation of the survival viability of cervical cancer cells (HeLa) under visible light induced photo-catalysis with facile synthesized WO 3 /ZnO nanocomposite.
المؤلفون: AbuMousa RA; Department of General Sciences, DES, Prince Sultan University, Riyadh 11586, Saudi Arabia., Baig U; Center for Research Excellence in Desalination, King Fahd University of Petroleum & Minerals, Saudi Arabia., Gondal MA; Laser Research Group, Physics Department & Center of Excellence in Nanotechnology, King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia., Dastageer MA; Laser Research Group, Physics Department & Center of Excellence in Nanotechnology, King Fahd University of Petroleum and Minerals, Dhahran 31261, Saudi Arabia., AlSalhi MS; Research Chair in Laser Diagnosis of Cancers, Department of Physics and Astronomy, College of Science, King Saud University, Riyadh, Saudi Arabia., Moftah B; Biomedical Physics Department, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.; Medical Physics Unit, McGill University, Montreal, Canada., Yahya Alqahtani F; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Akhter S; Electron Microscopy Unit, Institute for Research & Medical Consultations, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia., Sfouq Aleanizy F; Medical Physics Unit, McGill University, Montreal, Canada.
المصدر: Saudi journal of biological sciences [Saudi J Biol Sci] 2020 Jul; Vol. 27 (7), pp. 1743-1752. Date of Electronic Publication: 2020 Apr 27.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Saudi Biological Society Country of Publication: Saudi Arabia NLM ID: 101543796 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1319-562X (Print) Linking ISSN: 22137106 NLM ISO Abbreviation: Saudi J Biol Sci Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Riyadh : Saudi Biological Society : King Saud University, [2009]-
مستخلص: The photo catalytic degradation, a proven chemical process used for the decontamination of organic/inorganic pollutants and microorganisms in water was implemented. In this work for the selective killing of cervical cancer cells ( HeLa cells ) by using nano-composite of ZnO (Zinc Oxcide), WO 3 (tungsten oxide) and ( n-WO 3 /ZnO ) as a photo-catalyst under the irradiation of visible light. All the three nanostructured semiconducting materials (WO3, ZnO and n-WO3/ZnO) were synthesized by facile chemical precipitation method and their morphological and optical characterization studies were carried out to elucidate the observed enhancement in the photo-catalytic killing of HeLa cancer cells with n-WO3/ZnO as a photo-catalyst. After 60 min of photo-catalytic reaction with n-WO 3 /ZnO as a photo-catalyst, a survival viability of HeLa cancer cells as low as 15% was achieved (nearly 85% of killing), as compared to 65% of HeLa cancer cell survival viability (nearly 35% of killing) with individual use of WO 3 and ZnO as photo-catalysts under the same irradiation and experimental conditions. This improved photo-catalytic killing of HeLa cancer cells using n-WO 3 /ZnO in the visible spectral region is attributed to the enhanced visible light absorption and reduced electron hole recombination, characteristically brought about in the n-WO 3 /ZnO composite material. As photo-catalytic killing of the cancer cells can be selective, localized and reasonably efficient, in principle, this method can be considered as a non-invasive targeted treatment option for killing any type of cancer cells. HeLa cells, in particular are the cervical cancer cell and the tumors in and around cervix, containing HeLa cells can be non-surgically accessed and photo-catalytically treated with appropriate photo-catalyst and light source.
(© 2020 The Author(s).)
References: Cancers (Basel). 2011 Aug 12;3(3):3279-330. (PMID: 24212956)
Sci Rep. 2018 Oct 15;8(1):15224. (PMID: 30323306)
Annu Rev Biomed Eng. 2016 Jul 11;18:125-58. (PMID: 26863922)
J Photochem Photobiol B. 2018 Oct;187:113-119. (PMID: 30121421)
J Environ Sci Health A Tox Hazard Subst Environ Eng. 2008 Jan;43(1):70-7. (PMID: 18161560)
J Photochem Photobiol B. 2020 Jan;202:111713. (PMID: 31760373)
World J Clin Oncol. 2016 Feb 10;7(1):54-86. (PMID: 26862491)
Arch Pathol Lab Med. 2009 Sep;133(9):1463-7. (PMID: 19722756)
J Phys Chem B. 2018 Mar 15;122(10):2737-2746. (PMID: 29455530)
J Phys Chem Lett. 2020 May 7;11(9):3313-3319. (PMID: 32275826)
ACS Appl Mater Interfaces. 2016 Apr 27;8(16):10367-74. (PMID: 27045790)
Nanoscale. 2020 Feb 14;12(6):3846-3854. (PMID: 31995084)
J Cancer Sci Ther. 2009 Dec 1;1(2):1-4. (PMID: 20740081)
ACS Omega. 2018 Jul 18;3(7):8009-8016. (PMID: 31458939)
Photochem Photobiol Sci. 2019 Mar 1;18(3):641-680. (PMID: 30810559)
Nucleic Acids Res. 2019 Aug 22;47(14):7163-7181. (PMID: 31251805)
Chem Soc Rev. 2014 Aug 7;43(15):5234-44. (PMID: 24841176)
Materials (Basel). 2019 Oct 08;12(19):. (PMID: 31597336)
Int J Mol Sci. 2018 Oct 20;19(10):. (PMID: 30347840)
Nanobiomedicine (Rij). 2016 Jan 1;3:9. (PMID: 29942384)
فهرسة مساهمة: Keywords: Cancerous cells; HeLa cell line; Photo-catalytic killing; ZnO/WO3 nanocomposite
تواريخ الأحداث: Date Created: 20200623 Latest Revision: 20200928
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC7296502
DOI: 10.1016/j.sjbs.2020.04.038
PMID: 32565691
قاعدة البيانات: MEDLINE
الوصف
تدمد:1319-562X
DOI:10.1016/j.sjbs.2020.04.038