دورية أكاديمية
COVID-19 and cardiac arrhythmias.
| العنوان: | COVID-19 and cardiac arrhythmias. |
|---|---|
| المؤلفون: | Bhatla A; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Mayer MM; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Adusumalli S; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Hyman MC; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Oh E; Department of Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Tierney A; Department of Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Moss J; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Chahal AA; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Anesi G; Division of Pulmonary and Critical Care, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Denduluri S; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Domenico CM; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Arkles J; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Abella BS; Department of Emergency Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Bullinga JR; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Callans DJ; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Dixit S; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Epstein AE; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Frankel DS; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Garcia FC; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Kumareswaram R; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Nazarian S; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Riley MP; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Santangeli P; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Schaller RD; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Supple GE; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Lin D; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Marchlinski F; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania., Deo R; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: Rajat.Deo@pennmedicine.upenn.edu. |
| المصدر: | Heart rhythm [Heart Rhythm] 2020 Sep; Vol. 17 (9), pp. 1439-1444. Date of Electronic Publication: 2020 Jun 22. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 101200317 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1556-3871 (Electronic) Linking ISSN: 15475271 NLM ISO Abbreviation: Heart Rhythm Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: New York, NY : Elsevier, c2004- |
| مواضيع طبية MeSH: | Betacoronavirus*, Arrhythmias, Cardiac/*epidemiology , Coronavirus Infections/*complications , Heart Arrest/*epidemiology , Pneumonia, Viral/*complications, Adult ; Aged ; Arrhythmias, Cardiac/diagnosis ; Arrhythmias, Cardiac/therapy ; COVID-19 ; Cohort Studies ; Coronavirus Infections/mortality ; Coronavirus Infections/therapy ; Female ; Heart Arrest/diagnosis ; Heart Arrest/therapy ; Hospital Mortality ; Hospitalization ; Humans ; Incidence ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/mortality ; Pneumonia, Viral/therapy ; Risk Factors ; SARS-CoV-2 |
| مستخلص: | Background: Early studies suggest that coronavirus disease 2019 (COVID-19) is associated with a high incidence of cardiac arrhythmias. Severe acute respiratory syndrome coronavirus 2 infection may cause injury to cardiac myocytes and increase arrhythmia risk. Objectives: The purpose of this study was to evaluate the risk of cardiac arrest and arrhythmias including incident atrial fibrillation (AF), bradyarrhythmias, and nonsustained ventricular tachycardia (NSVT) in a large urban population hospitalized for COVID-19. We also evaluated correlations between the presence of these arrhythmias and mortality. Methods: We reviewed the characteristics of all patients with COVID-19 admitted to our center over a 9-week period. Throughout hospitalization, we evaluated the incidence of cardiac arrests, arrhythmias, and inpatient mortality. We also used logistic regression to evaluate age, sex, race, body mass index, prevalent cardiovascular disease, diabetes, hypertension, chronic kidney disease, and intensive care unit (ICU) status as potential risk factors for each arrhythmia. Results: Among 700 patients (mean age 50 ± 18 years; 45% men; 71% African American; 11% received ICU care), there were 9 cardiac arrests, 25 incident AF events, 9 clinically significant bradyarrhythmias, and 10 NSVTs. All cardiac arrests occurred in patients admitted to the ICU. In addition, admission to the ICU was associated with incident AF (odds ratio [OR] 4.68; 95% confidence interval [CI] 1.66-13.18) and NSVT (OR 8.92; 95% CI 1.73-46.06) after multivariable adjustment. Also, age and incident AF (OR 1.05; 95% CI 1.02-1.09) and prevalent heart failure and bradyarrhythmias (OR 9.75; 95% CI 1.95-48.65) were independently associated. Only cardiac arrests were associated with acute in-hospital mortality. Conclusion: Cardiac arrests and arrhythmias are likely the consequence of systemic illness and not solely the direct effects of COVID-19 infection. (Copyright © 2020. Published by Elsevier Inc.) |
| References: | JAMA. 2020 May 26;323(20):2052-2059. (PMID: 32320003) N Engl J Med. 2020 Jul 30;383(5):496-498. (PMID: 32348640) Thromb Res. 2020 Jul;191:148-150. (PMID: 32381264) Heart Rhythm. 2020 Sep;17(9):1463-1471. (PMID: 32387246) JAMA. 2020 Jun 23;323(24):2493-2502. (PMID: 32392282) N Engl J Med. 2020 May 21;382(21):e70. (PMID: 32374956) JACC Clin Electrophysiol. 2020 Sep;6(9):1189-1190. (PMID: 32972558) J Am Coll Cardiol. 2020 Jun 16;75(23):2950-2973. (PMID: 32311448) JAMA. 2020 Mar 17;323(11):1061-1069. (PMID: 32031570) JAMA Cardiol. 2020 Jul 1;5(7):811-818. (PMID: 32219356) |
| معلومات مُعتمدة: | L30 HL154200 United States HL NHLBI NIH HHS |
| فهرسة مساهمة: | Keywords: Arrhythmia; Atrial fibrillation; COVID-19; Cardiac arrest; Mortality; Nonsustained ventricular tachycardia |
| تواريخ الأحداث: | Date Created: 20200626 Date Completed: 20200909 Latest Revision: 20231111 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC7307518 |
| DOI: | 10.1016/j.hrthm.2020.06.016 |
| PMID: | 32585191 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1556-3871 |
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| DOI: | 10.1016/j.hrthm.2020.06.016 |