دورية أكاديمية
Dataset on sociability, cognitive function, gene and protein expression of molecules involved in social behavior, reward system and synapse function following early-life status epilepticus in Wistar rats.
العنوان: | Dataset on sociability, cognitive function, gene and protein expression of molecules involved in social behavior, reward system and synapse function following early-life status epilepticus in Wistar rats. |
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المؤلفون: | Pacífico AM; Developmental Disabilities Graduate Program. Mackenzie Presbyterian University, São Paulo, Brazil. Rua da Consolação, 930. Prédio 28, CEP 01302-907 São Paulo, SP, Brazil., Batista SP; Developmental Disabilities Graduate Program. Mackenzie Presbyterian University, São Paulo, Brazil. Rua da Consolação, 930. Prédio 28, CEP 01302-907 São Paulo, SP, Brazil., Ribeiro FT; Developmental Disabilities Graduate Program. Mackenzie Presbyterian University, São Paulo, Brazil. Rua da Consolação, 930. Prédio 28, CEP 01302-907 São Paulo, SP, Brazil., Santos PBD; Developmental Disabilities Graduate Program. Mackenzie Presbyterian University, São Paulo, Brazil. Rua da Consolação, 930. Prédio 28, CEP 01302-907 São Paulo, SP, Brazil., Silveira GB; Developmental Disabilities Graduate Program. Mackenzie Presbyterian University, São Paulo, Brazil. Rua da Consolação, 930. Prédio 28, CEP 01302-907 São Paulo, SP, Brazil., Pedrico do Nascimento BP; Developmental Disabilities Graduate Program. Mackenzie Presbyterian University, São Paulo, Brazil. Rua da Consolação, 930. Prédio 28, CEP 01302-907 São Paulo, SP, Brazil., Junior ED; Developmental Disabilities Graduate Program. Mackenzie Presbyterian University, São Paulo, Brazil. Rua da Consolação, 930. Prédio 28, CEP 01302-907 São Paulo, SP, Brazil., Barbosa GHL; Developmental Disabilities Graduate Program. Mackenzie Presbyterian University, São Paulo, Brazil. Rua da Consolação, 930. Prédio 28, CEP 01302-907 São Paulo, SP, Brazil., Ribeiro MO; Developmental Disabilities Graduate Program. Mackenzie Presbyterian University, São Paulo, Brazil. Rua da Consolação, 930. Prédio 28, CEP 01302-907 São Paulo, SP, Brazil., da Silva SG; Hospital do Câncer de Muriaé - Fundação Cristiano Varella, Muriaé, Brazil.; Centro Universitário UNIFAMINAS, Muriaé, Brazil., Cysneiros RM; Developmental Disabilities Graduate Program. Mackenzie Presbyterian University, São Paulo, Brazil. Rua da Consolação, 930. Prédio 28, CEP 01302-907 São Paulo, SP, Brazil. |
المصدر: | Data in brief [Data Brief] 2020 Jun 07; Vol. 31, pp. 105819. Date of Electronic Publication: 2020 Jun 07 (Print Publication: 2020). |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101654995 Publication Model: eCollection Cited Medium: Internet ISSN: 2352-3409 (Electronic) Linking ISSN: 23523409 NLM ISO Abbreviation: Data Brief Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Original Publication: [Amsterdam] : Elsevier B.V., [2014]- |
مستخلص: | Early-life status epilepticus produces deficit in social interaction and vocalization, enhances anxiety, no cognitive impairment and alters functional connectivity within the hippocampus (CA3-CA1) and between the hippocampus and prefrontal cortex [1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], but the underlying mechanisms remain unknown. This data article contains behavioral and molecular data of the adult male Wistar rats subjected to early life pilocarpine-induced seizures. Animal's behaviors were assessed to social memory and social motivation, working and reference memories and cognitive flexibility. The brain tissues (hypothalamus, hippocampus, amygdala, and striatum) were probed to gene and protein expression of molecules related to social behavior, reward system and synaptic function. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships which have, or could be perceived to have, influenced the work reported in this article. (© 2020 The Author(s).) |
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فهرسة مساهمة: | Keywords: Cognition; Early-life status epilepticus; Motivation; Oxytocin; Pilocarpine; Sociability |
تواريخ الأحداث: | Date Created: 20200630 Latest Revision: 20200928 |
رمز التحديث: | 20231215 |
مُعرف محوري في PubMed: | PMC7306614 |
DOI: | 10.1016/j.dib.2020.105819 |
PMID: | 32596424 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2352-3409 |
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DOI: | 10.1016/j.dib.2020.105819 |