دورية أكاديمية
Prevalence and predictors of precancerous cervical lesions among HIV-positive women in Jos, north-central Nigeria.
| العنوان: | Prevalence and predictors of precancerous cervical lesions among HIV-positive women in Jos, north-central Nigeria. |
|---|---|
| المؤلفون: | Daniel GO; Department of Nursing Science, College of Health Sciences, University of Jos, Jos, Nigeria., Musa J; Department of Obstetrics and Gynaecology, College of Health Sciences, University of Jos, Jos, Nigeria., Akindigh TM; Department of Zoology, University of Jos, Jos, Nigeria., Shinku F; Department of Anatomy, College of Health Sciences, University of Jos, Jos, Nigeria., Shuaibu SI; Department of Surgery, College of Health Sciences, University of Jos, Jos, Nigeria., Kwaghe B; Department of Histopathology, College of Health Sciences, University of Jos, Jos, Nigeria., Afolaranmi T; Department of Community Medicine, University of Jos, Jos, Nigeria., Okpala C; Stamina Research Office, University of Jos, Jos, Nigeria., Agbaji O; Department of Medicine, College of Health Sciences, University of Jos, Jos, Nigeria., Sagay A; Department of Obstetrics and Gynaecology, College of Health Sciences, University of Jos, Jos, Nigeria. |
| المصدر: | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics [Int J Gynaecol Obstet] 2020 Nov; Vol. 151 (2), pp. 253-259. Date of Electronic Publication: 2020 Aug 25. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley Country of Publication: United States NLM ID: 0210174 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3479 (Electronic) Linking ISSN: 00207292 NLM ISO Abbreviation: Int J Gynaecol Obstet Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2017- : Malden, MA : Wiley Original Publication: [New York, NY] Hoeber Medical Division, Harper & Row, [c1969- |
| مواضيع طبية MeSH: | HIV Infections* , HIV-1*, Neoplasms, Squamous Cell/*epidemiology , Uterine Cervical Neoplasms/*epidemiology , Uterine Cervical Dysplasia/*epidemiology, Adolescent ; Adult ; Cross-Sectional Studies ; Female ; Humans ; Middle Aged ; Neoplasms, Squamous Cell/etiology ; Neoplasms, Squamous Cell/pathology ; Nigeria/epidemiology ; Prevalence ; Risk Factors ; Socioeconomic Factors ; Uterine Cervical Neoplasms/etiology ; Uterine Cervical Neoplasms/pathology ; Vaginal Smears ; Young Adult ; Uterine Cervical Dysplasia/etiology ; Uterine Cervical Dysplasia/pathology |
| مستخلص: | Objective: To determine the prevalence and predictors of precancerous cervical lesions among HIV-positive women in Jos, Nigeria. Methods: A cross-sectional study was conducted from October 2017 to January 2018 among 326 HIV-positive women. Cervical smears were collected for examination at the AIDS Preventive Initiative of Nigeria clinics of Jos University Teaching Hospital (JUTH) and Bingham University Teaching Hospital (BhUTH), Jos, Nigeria. Demographic characteristics of participants were documented using a structured questionnaire. Data were entered and analyzed using SPSS version 21. Results: Of the 326 participants, precancerous cervical lesions were present in 40 (12.2%) women: 4 (1.2%) had atypical squamous cells of undetermined significance, 19 (5.8%) had low-grade squamous intraepithelial lesions, 1 (0.3%) had atypical squamous cells cannot exclude high-grade squamous intraepithelial lesions, 13 (4.0%) had high-grade squamous intraepithelial lesions, and 3 (0.9%) had high-grade squamous intraepithelial lesions, suspected for invasion. The multivariate logistics regression model showed that parity (odds ratio 3.4, 95% confidence interval 1.3-9.5, P=0.043) was a significant predictor of precancerous cervical lesions. Conclusion: The prevalence of precancerous cervical lesions among HIV-infected women is relatively low compared to earlier reported prevalence in an HIV population in Jos. Increasing parity was a significant predictor. (© 2020 International Federation of Gynecology and Obstetrics.) |
| References: | Black E, Richmond R. Prevention of cervical cancer in Sub-Saharan Africa; The advantages and Challenges of HPV Vaccination. Vaccines. 2018;6:1-8. MbouumbaBouassa RS, Prazuck T, Lethu T, Meye JF, Bele L. Cervical cancer in Sub-Saharan Africa: An emerging and preventable disease associated with oncogenic human papilloma virus. Med Sante Trop. 2017;27:16-22. Oche MO, Kaoje AU, Gana G, Ango JT. Cancer of the cervix and cervical screening: Current knowledge, attitude, and practices of female health workers in Sokoto, Nigeria. Int J Med Sci. 2013;5:184-190. Ferlay J, Shin H, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN. Int J Cancer. 2010;127:2893-2917. Arbyn M, Castellsague X, De-Sanjose S, et al. Worldwide burden of cervical cancer in 2008. Ann Oncol. 2011;22:2675-2686. Nkfusai NC, Mubah TM, Yakam BM, Tamber TA, Cumber SN. Prevalence of precancerous lesions in women attending Mezam Polyclinic Bamenda, Cameroon. P Afr Med J. 2019; 32: 174. Swende TZ, NgwanSD SLT. Prevalence and risk factors for cervical squamousintraepithelial lesions among women infected with HIV-1 in Makurdi, Nigeria. Int J Womens Health. 2012;4:55-60. Pfaendler KS, Mwanahamuntu MH, Hicks ML, Parham GP. Microinvasive carcinoma of the cervix. Global Libr Womens Med. 2008;1756-2228. Canadian Cancer Society. Cervical cancer; Precancerous conditions of the cervix. Canadian Cancer Society 2018. www.cancer.ca. Accessed February 6, 2019. Ononogu U, Almujtaba M, Modibbo F, et al. Cervical cancer risk factors among HIV-infected Nigerian women. BMC Public Health. 2013;13:582. Utoo BT, Utoo PM, Ngwu SD, AnzakuSA DMA. Cervical intraepithelial neoplasia; prevalence, risk factors, and utilization of screening services among an urban population in Nigeria. Trop J Obstet Gynaecol. 2016; 33: 279-283. Getinet M, Gelaw B, Sisay A, Mahmoud E. Prevalence and predictors of pap smear cervical epithelial cell abnormality among HIV positive and negative women attending gynecological examination in cervical cancer screening center at DebreMarkos Referral Hospital, East Gojjam, Northwest Ethiopia. BMC Clin Pathol. 2015;15:16. Agaba PA, Thacher TD, Ekwempu CC, Idoko JA. Cervical dysplasia in Nigerian women infected with HIV. Int J Gynecol and Obstet. 2009;107:99-102. Dim CC, Ezegwui H, Ikeme AC, Onyedum CC. Prevalence of Cervical Squamous intraepithelial lesions among HIV positive women in Enugu, South Eastern Nigeria. J Obst Gynaecol. 2011;31:759-762. Teame H, Addissie A, Ayele W, et al. Factors associated with cervical precancerous lesions among women screened for cervical cancer in Addis Ababa, Ethiopia: A case-control study. PLoS One. 2018;13:e0191506. Gedefaw A, Astakie A, Tessema GA. The prevalence of precancerous cervical cancer lesion among HIV infected women in southern Ethiopia; a cross-sectional study. PLoS One. 2013;8:e84519. Memiah P, Mbuthia W, Kiiru G, et al. Prevalence and risk factors associated with precancerous cervical cancer lesions among HIV infected women in resource-limited settings. AIDS Res Treat. 2012;2012:1-7. Weldegebreal F, Worku T. Precancerous cervical lesion among HIV-positive women in Sub-Saharan Africa: A systematic review and meta-analysis. Can Control. 2019;26:1-11. Atashili J, Smith JS, Adimora AA, Eron J, Miller WC, Myers E. Potential impact of antiretroviral therapy and screening on cervical cancer mortality in HIV-positive women in sub-Saharan Africa: A simulation. PLoS One. 2011;6:e18527. Voltaggio L, Cimino-Mathews A, Bishop JA, et al. Current concepts in the diagnosis and pathobiology of intraepithelial neoplasia: A review by organ system. CA Can J Clin. 2016;66:408-436. Solé-Sedeno J, Mancebo G, Miralpeix E, et al. Utility of Human Papillomavirus genotyping in the management of low-grade squamous intraepithelial lesions. J Low Genit Tract Dis. 2018;22:13-16. Massad LS, Einstein MH, Huh WK, et al. 2012 updated consensus guidelines for the management of abnormal cervical cancer screening tests and cancer precursors. J low Genit Tract Dis. 2013;17:S1-S27. Donkoh ET, Agyemang-Yeboah F, Asmah RH, Wiredu EK. Prevalence of cervical cancer and pre-cancerous lesions among unscreened women in Kumasi, Ghana. Medicine. 2019;98:e14600. Atashili J, Miller WC, Smith JS, et al. Age trends in the prevalence of cervical squamous intraepithelial lesions among HIV-positive women in Cameroon: A cross-sectional study. BMC Res Notes. 2012;5:590. Belayneh T, Mitiku H, Weldegebreal F. Precancerous cervical lesion and associated factors among HIV-infected women on ART in Amhara Regional State, Ethiopia: A hospital-based cross-sectional study. Int J Health Sc. 2019;13:4-8. |
| معلومات مُعتمدة: | Fogarty International Center (FIC); National Institute of Health; National Institute of Nursing Research (NINR); National Institute of Neurological Disorders and Stroke (NINDS); U.S. Department of Health and Human Services; United States HRSA HRSA HHS; Centers for Disease Control and Prevention (CDC); United States HRSA HRSA HHS |
| فهرسة مساهمة: | Keywords: Cervical cancer; HIV; Nigeria; Precancer; Screening |
| تواريخ الأحداث: | Date Created: 20200720 Date Completed: 20201229 Latest Revision: 20221207 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1002/ijgo.13312 |
| PMID: | 32683675 |
| قاعدة البيانات: | MEDLINE |
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