دورية أكاديمية
Evaluating the Impact of Programmatic Mass Drug Administration for Malaria in Zambia Using Routine Incidence Data.
| العنوان: | Evaluating the Impact of Programmatic Mass Drug Administration for Malaria in Zambia Using Routine Incidence Data. |
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| المؤلفون: | Fraser M; PATH Malaria Control and Elimination Partnership in Africa (MACEPA), Seattle, Washington, USA., Miller JM; PATH MACEPA, Lusaka, Zambia., Silumbe K; PATH MACEPA, Lusaka, Zambia., Hainsworth M; PATH Malaria Control and Elimination Partnership in Africa (MACEPA), Seattle, Washington, USA., Mudenda M; National Malaria Elimination Centre, Zambia Ministry of Health, Lusaka, Zambia., Hamainza B; National Malaria Elimination Centre, Zambia Ministry of Health, Lusaka, Zambia., Moonga H; National Malaria Elimination Centre, Zambia Ministry of Health, Lusaka, Zambia., Chizema Kawesha E; National Malaria Elimination Centre, Zambia Ministry of Health, Lusaka, Zambia., Mercer LD; PATH Malaria Control and Elimination Partnership in Africa (MACEPA), Seattle, Washington, USA., Bennett A; PATH Malaria Control and Elimination Partnership in Africa (MACEPA), Seattle, Washington, USA.; University of California San Francisco, San Francisco, California, USA., Schneider K; PATH Malaria Control and Elimination Partnership in Africa (MACEPA), Seattle, Washington, USA., Slater HC; PATH Malaria Control and Elimination Partnership in Africa (MACEPA), Seattle, Washington, USA., Eisele TP; Center for Applied Malaria Research and Evaluation, Department of Tropical Medicine, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA., Guinovart C; PATH Malaria Control and Elimination Partnership in Africa (MACEPA), Seattle, Washington, USA.; Barcelona Institute for Global Health (ISGlobal), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain. |
| المصدر: | The Journal of infectious diseases [J Infect Dis] 2022 Apr 19; Vol. 225 (8), pp. 1415-1423. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Jan. 2011- : Oxford : Oxford University Press Original Publication: 1904-2010 : Chicago, IL : University of Chicago Press |
| مواضيع طبية MeSH: | Antimalarials*/therapeutic use , Malaria*/drug therapy , Malaria*/epidemiology , Malaria*/prevention & control, Humans ; Incidence ; Mass Drug Administration ; Zambia/epidemiology |
| مستخلص: | Background: In 2016, the Zambian National Malaria Elimination Centre started programmatic mass drug administration (pMDA) campaigns with dihydroartemisinin-piperaquine as a malaria elimination tool in Southern Province. Two rounds were administered, 2 months apart (coverage 70% and 57%, respectively). We evaluated the impact of 1 year of pMDA on malaria incidence using routine data. Methods: We conducted an interrupted time series with comparison group analysis on monthly incidence data collected at the health facility catchment area (HFCA) level, with a negative binomial model using generalized estimating equations. Programmatic mass drug administration was conducted in HFCAs with greater than 50 cases/1000 people per year. Ten HFCAs with incidence rates marginally above this threshold (pMDA group) were compared with 20 HFCAs marginally below (comparison group). Results: The pMDA HFCAs saw a 46% greater decrease in incidence at the time of intervention than the comparison areas (incidence rate ratio = 0.536; confidence interval = 0.337-0.852); however, incidence increased toward the end of the season. No HFCAs saw a transmission interruption. Conclusions: Programmatic mass drug administration, implemented during 1 year with imperfect coverage in low transmission areas with suboptimal vector control coverage, significantly reduced incidence. However, elimination will require additional tools. Routine data are important resources for programmatic impact evaluations and should be considered for future analyses. (© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America.) |
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| فهرسة مساهمة: | Keywords: impact evaluation; malaria; mass drug administration; routine data |
| المشرفين على المادة: | 0 (Antimalarials) |
| تواريخ الأحداث: | Date Created: 20200722 Date Completed: 20220420 Latest Revision: 20220716 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC9016426 |
| DOI: | 10.1093/infdis/jiaa434 |
| PMID: | 32691047 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1537-6613 |
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| DOI: | 10.1093/infdis/jiaa434 |