دورية أكاديمية

High-risk and Long-term Opioid Prescribing to Military Spouses in the Millennium Cohort Family Study.

التفاصيل البيبلوغرافية
العنوان: High-risk and Long-term Opioid Prescribing to Military Spouses in the Millennium Cohort Family Study.
المؤلفون: McDonald DC; Abt Associates, 6130 Executive Boulevard, Rockville, MD, 20852., Radakrishnan S; Abt Associates, 6130 Executive Boulevard, Rockville, MD, 20852., Sparks AC; Abt Associates, 6130 Executive Boulevard, Rockville, MD, 20852., Corry NH; Abt Associates, 6130 Executive Boulevard, Rockville, MD, 20852., Carballo CE; Leidos, 11951 Freedom Dr., Reston, VA 20190.; Naval Health Research Center, 140 Sylvester Rd., San Diego, CA 92106., Carlson K; Abt Associates, 6130 Executive Boulevard, Rockville, MD, 20852., Stander VA; Naval Health Research Center, 140 Sylvester Rd., San Diego, CA 92106.
المصدر: Military medicine [Mil Med] 2020 Sep 18; Vol. 185 (9-10), pp. e1759-e1769.
نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
اللغة: English
بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 2984771R Publication Model: Print Cited Medium: Internet ISSN: 1930-613X (Electronic) Linking ISSN: 00264075 NLM ISO Abbreviation: Mil Med Subsets: MEDLINE
أسماء مطبوعة: Publication: 2018- : Oxford : Oxford University Press
Original Publication: Washington, D.C. : Association of Military Surgeons, United States, 1955-
مواضيع طبية MeSH: Analgesics, Opioid*/therapeutic use, Cohort Studies ; Female ; Humans ; Male ; Opioid-Related Disorders/drug therapy ; Practice Patterns, Physicians' ; Spouses
مستخلص: Introduction: The use and misuse of opioids by active service members has been examined in several studies, but little is known about their spouses' opioid use. This study estimates the number of military spouses who received high-risk or long-term opioid prescriptions between 2010 and 2014, and addresses how the Military Health System can help prevent risky prescribing in order to improve military force readiness.
Materials and Methods: This study used data from the Millennium Cohort Family Study, a nationwide survey of 9,872 spouses of service members with 2 to 5 years of military service, augmented with information from the military's Pharmacy Data Transaction Service about prescriptions for controlled drugs dispensed to these service members' spouses. Our objectives were to estimate the prevalence of opioid prescribing indicative of long-term use (≥60 day supply or at least one extended-release opioid prescription in any 3-month period) and, separately, high-risk use (daily dosage of ≥90 morphine mg equivalent or total dosage of ≥8,190 morphine mg equivalent, or prescriptions from more than three pharmacies, or concurrent prescriptions). For each of these dependent variables, we conducted bivariate analyses and multiple logistic regression models using information about spouses' physical health, sociodemographic characteristics, substance use behaviors, perceived social support, and stresses associated with military stress, among others. Informed consent, including consent to link survey responses to medical and personnel records, was obtained from all participants. The Naval Health Research Center's Institutional Review Board and the Office of Management and Budget approved the study.
Results: Spouses were predominantly female (86%), had not served in the military themselves (79%), and were spouses of enlisted (91%) active duty (86%) service members. Almost half (47.6%) of spouses obtained at least one opioid prescription during the 2-year observation window, and 8.5% had received opioid prescriptions that posed risk to their health. About 7% met the criteria for receipt of high-risk opioid prescriptions, 3% obtained opioids from three or more pharmacies during a 3-month period, and 4% of spouses who received any opioids received both long-term and high-risk prescriptions. Adverse childhood experiences, physical pain, and lack of social support were associated with increased odds of obtaining high-risk opioid prescriptions.
Conclusions: Approximately 48% of military spouses had used Military Health System insurance to fill at least one opioid prescription during the 2-year observation period. The Department of Defense has taken measures to minimize high-risk opioid prescribing, including passing prescribing guidelines in 2017, establishing the controlled drug management analysis reporting tool, establishing a pain management education and training program, and more. These efforts should continue to expand as reducing the numbers of service members and spouses at risk for adverse events may be effective in reducing opioid misuse and improve the overall health and safety of military spouses and thus, the readiness of the U.S. Armed Forces.
(Published by Oxford University Press on behalf of Association of Military Surgeons of the United States 2020. This work is written by (a) US Government employee(s) and is in the public domain in the US.)
المشرفين على المادة: 0 (Analgesics, Opioid)
تواريخ الأحداث: Date Created: 20200723 Date Completed: 20210413 Latest Revision: 20210413
رمز التحديث: 20231215
DOI: 10.1093/milmed/usaa146
PMID: 32696969
قاعدة البيانات: MEDLINE
الوصف
تدمد:1930-613X
DOI:10.1093/milmed/usaa146