دورية أكاديمية
Clinical presentation and microbiology of acute salivary gland infections.
| العنوان: | Clinical presentation and microbiology of acute salivary gland infections. |
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| المؤلفون: | Danstrup CS; Christian.danstrup@gmail.com., Münch HJ, Klug TE, Fuursted K, Ovesen T |
| المصدر: | Danish medical journal [Dan Med J] 2020 Jun 01; Vol. 67 (6). Date of Electronic Publication: 2020 Jun 01. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Danish Medical Association Country of Publication: Denmark NLM ID: 101576205 Publication Model: Electronic Cited Medium: Internet ISSN: 2245-1919 (Electronic) Linking ISSN: 22451919 NLM ISO Abbreviation: Dan Med J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Copenhagen : Danish Medical Association |
| مواضيع طبية MeSH: | Anti-Bacterial Agents/*pharmacology , Penicillins/*pharmacology , Sialadenitis/*drug therapy , Staphylococcal Infections/*drug therapy , Staphylococcus aureus/*isolation & purification, Acute Disease ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Female ; Humans ; Male ; Middle Aged ; Otorhinolaryngologic Surgical Procedures ; Perioperative Care ; Sialadenitis/microbiology ; Young Adult |
| مستخلص: | Introduction: Acute salivary gland infections (ASI) have been associated with poor outcome in elderly and postoperative patients. Perioperative care and treatment of co-morbidities have improved considerably, but most of our knowledge regarding ASI dates back several decades. The aim of this study was to describe the microbiology and treatment of ASI in a large post-millennial cohort. Methods: All patients with ASI admitted to the Department of Otorhinolaryngology - Head and Neck Surgery, Aarhus University Hospital in the period from 2001 to 2017 were included. Results: In total, 157 patients with ASI were included. The parotid gland (PG) was affected in 89 (57%) cases and the submandibular gland (SMG) in 68 (43%) cases. The most prevalent bacterial findings were viridans streptococci (25 isolates) and Staphylococcus aureus (19 isolates). S. aureus was almost exclusively found in PG (17/19 cases). S. aureus-positive cases showed a significantly higher inflammatory response than other bacteria (C-reactive protein, p = 0.008 and absolute neutrophil count, p = 0.0108). Conclusions: S. aureus is a significant pathogen in ASI and especially in PG cases. Other pathogens may play a role in the development of SMG infections. Based on the bacterial findings in this study, we recommend penicillinase-resistant penicillin as first-line treatment in ASI. Funding: none Trial registration: not relevant. The Danish Data Protection Agency approved the project. (Articles published in the DMJ are “open access”. This means that the articles are distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits any non-commercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.) |
| المشرفين على المادة: | 0 (Anti-Bacterial Agents) 0 (Penicillins) |
| تواريخ الأحداث: | Date Created: 20200804 Date Completed: 20210505 Latest Revision: 20210505 |
| رمز التحديث: | 20221213 |
| PMID: | 32741433 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2245-1919 |
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