دورية أكاديمية
Transfusion of ABO non-identical platelets increases the severity of trauma patients at ICU admission.
| العنوان: | Transfusion of ABO non-identical platelets increases the severity of trauma patients at ICU admission. |
|---|---|
| المؤلفون: | Silva ALO; Fundação Pró-Sangue (Hemocentro), São Paulo, SP, Brazil., Bassolli L; Faculdade de Medicina da Universidade de São Paulo (FM USP), São Paulo, SP, Brazil., Ferreira P; Faculdade de Medicina da Universidade de São Paulo (FM USP), São Paulo, SP, Brazil., Utiyama E; Faculdade de Medicina da Universidade de São Paulo (FM USP), São Paulo, SP, Brazil., Dezan MR; Fundação Pró-Sangue (Hemocentro), São Paulo, SP, Brazil., Costa-Neto A; Faculdade de Medicina da Universidade de São Paulo (FM USP), São Paulo, SP, Brazil., Conrado MCAV; Fundação Pró-Sangue (Hemocentro), São Paulo, SP, Brazil., Oliveira VB; Fundação Pró-Sangue (Hemocentro), São Paulo, SP, Brazil., Bonifácio SL; Fundação Pró-Sangue (Hemocentro), São Paulo, SP, Brazil., Fernandes FLA; Faculdade de Medicina da Universidade de São Paulo (FM USP), São Paulo, SP, Brazil; Departamento de Pneumologia, Faculdade de Medicina da Universidade de São Paulo, SP, Brazil., Rocha V; Fundação Pró-Sangue (Hemocentro), São Paulo, SP, Brazil; Faculdade de Medicina da Universidade de São Paulo (FM USP), São Paulo, SP, Brazil; Churchill Hospital, NHS BT, Oxford University, Oxford, United Kingdom., Mendrone-Júnior A; Fundação Pró-Sangue (Hemocentro), São Paulo, SP, Brazil., Dinardo CL; Fundação Pró-Sangue (Hemocentro), São Paulo, SP, Brazil; Faculdade de Medicina da Universidade de São Paulo (FM USP), São Paulo, SP, Brazil; Instituto de Medicina Tropical, University of São Paulo, São Paulo, SP, Brazil. Electronic address: carlaluana@usp.br. |
| المصدر: | Hematology, transfusion and cell therapy [Hematol Transfus Cell Ther] 2021 Jul-Sep; Vol. 43 (3), pp. 287-294. Date of Electronic Publication: 2020 Aug 06. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Editora Ltda Country of Publication: Brazil NLM ID: 101725732 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2531-1387 (Electronic) Linking ISSN: 25311379 NLM ISO Abbreviation: Hematol Transfus Cell Ther Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: [Rio de Janeiro, Brazil] : Elsevier Editora Ltda, [2018]- |
| مستخلص: | Background: Transfusion of ABO-compatible non-identical platelets (PTLs), fresh plasma (FP) and red blood cells (RBCs) has been associated with increased morbidity and mortality of recipients. Trauma victims are frequently exposed to ABO non-identical products, given the need for emergency transfusions. Our goal was to evaluate the impact of the transfusion of ABO non-identical blood products on the severity and all-cause 30-day mortality of trauma patients. Methods: This was a retrospective single-center cohort, which included trauma patients who received emergency transfusions in the first 24 h of hospitalization. Patients were divided in two groups according to the use of <3 or ≥3 ABO non-identical blood products. The patient severity, measured by the Acute Physiology and Chronic Health Evaluation (APACHEII) score at ICU admission, and the 30-day mortality were compared between groups. Results: Two hundred and sixteen trauma patients were enrolled. Of these, 21.3% received ≥3 ABO non-identical blood products (RBCs, PLTs and FP or cryoprecipitate). The transfusion of ≥3 ABO non-identical blood products in the first 24 h of hospitalization was independently associated with a higher APACHEII score at ICU admission (OR = 3.28 and CI95% = 1.48-7.16). Transfusion of at least one unit of ABO non-identical PTLs was also associated with severity (OR = 10.89 and CI95% = 3.38-38.49). Transfusion of ABO non-identical blood products was not associated with a higher 30-day mortality in the studied cohort. Conclusion: The transfusion of ABO non-identical blood products and, especially, of ABO non-identical PLTs may be associated with the greater severity of trauma patients at ICU admission. The transfusion of ABO non-identical blood products in the trauma setting is not without risks. (Copyright © 2020 Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular. Published by Elsevier España, S.L.U. All rights reserved.) |
| References: | Anesthesiology. 2018 Mar;128(3):650-656. (PMID: 29251646) Arch Surg. 2010 Sep;145(9):899-906. (PMID: 20855762) Vox Sang. 2009 May;96(4):316-23. (PMID: 19254234) Br J Anaesth. 2000 Sep;85(3):487-91. (PMID: 11103199) Transfusion. 2015 Feb;55(2):348-56. (PMID: 25178153) Crit Care Med. 1985 Oct;13(10):818-29. (PMID: 3928249) Transfusion. 2004 Jun;44(6):809-13. (PMID: 15157244) Curr Opin Hematol. 2012 Nov;19(6):475-9. (PMID: 22914587) Transfusion. 2016 Mar;56(3):550-7. (PMID: 26472598) Vox Sang. 2011 Jul;101(1):55-60. (PMID: 21414009) Transfusion. 1999 Nov-Dec;39(11-12):1273-4. (PMID: 10604259) Rev Bras Hematol Hemoter. 2015 Jul-Aug;37(4):217-22. (PMID: 26190423) Anesth Analg. 2017 Dec;125(6):2045-2055. (PMID: 28857793) Transfusion. 2001 Jun;41(6):790-3. (PMID: 11399821) |
| فهرسة مساهمة: | Keywords: Abo; Non identical; Platelets; Transfusion; Trauma |
| تواريخ الأحداث: | Date Created: 20200817 Latest Revision: 20210925 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC8446227 |
| DOI: | 10.1016/j.htct.2020.06.011 |
| PMID: | 32798060 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 2531-1387 |
|---|---|
| DOI: | 10.1016/j.htct.2020.06.011 |