| المؤلفون: |
Wong CTT; Department of Chemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China., Chu JCH; Department of Chemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China., Ha SYY; Department of Chemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China., Wong RCH; Department of Chemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China., Dai G; Department of Chemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China., Kwong TT; Department of Clinical Oncology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China., Wong CH; Department of Clinical Oncology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China., Ng DKP; Department of Chemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China. |
| مستخلص: |
A phthalaldehyde-substituted phthalocyanine has been synthesized that can conjugate with a range of biomolecules, including peptides, monosaccharides, lipids, and DNAs, and be immobilized on the surface of bovine serum album nanoparticles and glass slides using the versatile and efficient phthalaldehyde-amine capture reactions. The light-induced cytotoxic effects of the latter two materials have also been examined against cancer cells and bacteria, respectively, showing that they are highly efficient photosensitizing systems for photodynamic therapy. |
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