دورية أكاديمية
Comparing the Antileishmanial Activity of Gold(I) and Gold(III) Compounds in L. amazonensis and L. braziliensis in Vitro.
العنوان: | Comparing the Antileishmanial Activity of Gold(I) and Gold(III) Compounds in L. amazonensis and L. braziliensis in Vitro. |
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المؤلفون: | Minori K; Department of Animal Biology, Biology Institute, University of Campinas (UNICAMP), Rua Monteiro Lobato, 255, 13083-862., Campinas, SP, Brazil., Rosa LB; Department of Animal Biology, Biology Institute, University of Campinas (UNICAMP), Rua Monteiro Lobato, 255, 13083-862., Campinas, SP, Brazil., Bonsignore R; Department of Chemistry, Technical University of Munich (TUM), Lichtenbergstraße 4, 85748, Garching b. München, Germany., Casini A; Department of Chemistry, Technical University of Munich (TUM), Lichtenbergstraße 4, 85748, Garching b. München, Germany., Miguel DC; Department of Animal Biology, Biology Institute, University of Campinas (UNICAMP), Rua Monteiro Lobato, 255, 13083-862., Campinas, SP, Brazil. |
المصدر: | ChemMedChem [ChemMedChem] 2020 Nov 18; Vol. 15 (22), pp. 2146-2150. Date of Electronic Publication: 2020 Sep 28. |
نوع المنشور: | Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Weinheim, Germany : Wiley-VCH, c2006- |
مواضيع طبية MeSH: | Antiprotozoal Agents/*pharmacology , Leishmania/*drug effects , Organogold Compounds/*pharmacology, Animals ; Antiprotozoal Agents/chemistry ; Cells, Cultured ; Mice ; Mice, Inbred BALB C ; Molecular Structure ; Organogold Compounds/chemistry ; Parasitic Sensitivity Tests |
مستخلص: | A series of mononuclear coordination or organometallic Au I /Au III complexes (1-9) have been comparatively studied in vitro for their antileishmanial activity against promastigotes and amastigotes, the clinically relevant parasite form, of Leishmania amazonensis and Leishmania braziliensis. One of the cationic Au I bis-N-heterocyclic carbenes (3) has low EC (© 2020 The Authors. Published by Wiley-VCH GmbH.) |
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فهرسة مساهمة: | Keywords: amastigotes; antiprotozoal agents; gold compounds; leishmaniasis; promastigotes |
المشرفين على المادة: | 0 (Antiprotozoal Agents) 0 (Organogold Compounds) |
تواريخ الأحداث: | Date Created: 20200825 Date Completed: 20210914 Latest Revision: 20231110 |
رمز التحديث: | 20240628 |
مُعرف محوري في PubMed: | PMC7756297 |
DOI: | 10.1002/cmdc.202000536 |
PMID: | 32830445 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1860-7187 |
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DOI: | 10.1002/cmdc.202000536 |