دورية أكاديمية
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Forensic DNA Profiling: Autosomal Short Tandem Repeat as a Prominent Marker in Crime Investigation.

التفاصيل البيبلوغرافية
العنوان: Forensic DNA Profiling: Autosomal Short Tandem Repeat as a Prominent Marker in Crime Investigation.
المؤلفون: Nwawuba Stanley U; Centre for Forensic Programmes and DNA Studies, University of Benin, Benin City, Nigeria., Mohammed Khadija A; Molecular Drug Metabolism and Toxicology, Department of Biochemistry, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria., Bukola AT; Defence Headquarters Garrison, Abuja, Nigeria., Omusi Precious I; Department of Medical Laboratory Science, College of Medicine, University of Benin, Benin City, Nigeria., Ayevbuomwan Davidson E; Department of Biochemistry, Faculty of Life Sciences, University of Benin, Benin City, Nigeria.
المصدر: The Malaysian journal of medical sciences : MJMS [Malays J Med Sci] 2020 Jul; Vol. 27 (4), pp. 22-35. Date of Electronic Publication: 2020 Aug 19.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Universiti Sains Malaysia Press Country of Publication: Malaysia NLM ID: 101126308 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1394-195X (Print) Linking ISSN: 1394195X NLM ISO Abbreviation: Malays J Med Sci Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: [Pulau Pinang, Malaysia] : Universiti Sains Malaysia Press
Original Publication: [Kubang Kerian, Kelantan, Malaysia] : School of Medical Sciences, Universiti Sains Malaysia,
مستخلص: Short tandem repeat (STR) typing continues to be the primary workhorse in forensic DNA profiling. Therefore, the present review discusses the prominent role of STR marker in criminal justice system. All over the world, deoxyribonucleic acid (DNA) profiling provides evidence that may be used to convict criminals, as an irrefutable proof of wrongful convictions, invaluable links to the actual perpetrators of crimes, and could also deter some offenders from committing more serious offences. Clearly, DNA profiling tools have also aided forensic scientists to re-evaluate old cases that were considered closed as a result of inadequate evidence. In carrying out this review, a comprehensive electronic literature search using PubMed, ScienceDirect, Google Scholar and Google Search were used, and all works meeting the subject matter were considered, including reviews, retrospective studies, observational studies and original articles. Case reports presented here, further demonstrates the crucial role of forensic DNA profiling in mitigating and providing compelling evidence for the resolution of crimes. For case report 1, there was a 100% match between the DNA recovered from the items found in the crime scene, and the suspect's DNA sample collected via buccal swab following 15 STR loci examination. Case report 2 further highlights the indispensable contribution of DNA database in solving crime. Therefore, it has become very necessary for developing countries like Nigeria to develop a national DNA database and make policies and legislatures that will further expand and enable the practice of forensic genetics, particularly DNA profiling.
Competing Interests: Conflict of Interest None.
(© Penerbit Universiti Sains Malaysia, 2020.)
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فهرسة مساهمة: Keywords: DNA database; DNA profiling; forensic DNA profiling; forensic genetics; short tandem repeat typing
تواريخ الأحداث: Date Created: 20200901 Latest Revision: 20200928
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC7444828
DOI: 10.21315/mjms2020.27.4.3
PMID: 32863743
قاعدة البيانات: MEDLINE
الوصف
تدمد:1394-195X
DOI:10.21315/mjms2020.27.4.3